AC+T SEs

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  • Trvler
    Trvler Member Posts: 3,159
    edited April 2015

    Leigh: All I can tell you is that I had a pretty easy time the first time and I am having an easy time the second. So I am hopeful for you. Also, if you had any bone pain and your white cell count is high, they might ease off the Neulasta. I had 6 (whatever they measure it in) the first time and 4 the second and virtually no bone pain at all.

  • Leighrh
    Leighrh Member Posts: 317
    edited April 2015

    I did not have the neulasta... hopefully that continues.  I'll do blood work before on Thursday and hopefully I am good to continue to not get it!

  • rleepac
    rleepac Member Posts: 755
    edited April 2015

    SupperNannyMom - so sorry to hear about the clot! Looks like a Lovenox shot - yes?

  • Kicks
    Kicks Member Posts: 4,131
    edited April 2015

    Supernannymom - Not all react the same with different drugs. For some A/C is easier than Taxol - for some Taxol is easier than A/C. No matter which was 'worse', usually one will be easier than the other but only time will tell. For me, A/C was easy - did not slow me down at all but with Taxol I was completely and utterly exhausted the entire time.

  • Trvler
    Trvler Member Posts: 3,159
    edited April 2015

    Super: Just want to let you know I am thinking about you.

  • Supernannymom
    Supernannymom Member Posts: 50
    edited April 2015

    Allison - Thank you!!!

    Bek - yes Lovenox twice a day...in the stomach...yay...lol!


    Kicks - very good point about SE's being different for each person. I was really hoping that my SE's would be minimal...but the nausea has gotten me...

  • Kicks
    Kicks Member Posts: 4,131
    edited April 2015

    Supernannymom - I never had any nausea at all. While on A/C I did 'religiously' take all the anti- nausea meds. 1/2 way through Taxol I decided not to take any more anti-nausea meds and never had any issues with nausea at all. Talked with Dr and several RNs and they said that what experienced with pregnancy could indicate how bad Chemo nausea might be. I had had NO morning sickness with either Son and no Chemo nausea at all - so there may be a correlation?

  • SweetHope
    SweetHope Member Posts: 439
    edited April 2015

    Day 6 and 7 were like the worst labor pains that never let up. MO prescribed a muscle relaxer Flexeril which when combined with pain med, Norco, worked. MO is switching me from DD Taxol every two weeks to weekly Taxol which is a lower dose. She feels that weekly dose without Neulasta might work for me. Fingers are crossed.


  • Trvler
    Trvler Member Posts: 3,159
    edited April 2015

    I hope it does. I honestly don't know why they still give biweekly Taxol. I was in my car waiting for my daughter to come out from school yesterday and I started getting brave enough to start reading about Taxol. I immediately found an article that said the outcomes with weekly and biweekly taxol are virtually identical so why the F people give it biweekly is beyond me. That played a part in the MO I chose to some degree, too.

  • SweetHope
    SweetHope Member Posts: 439
    edited April 2015

    I chose bi-weekly to be finished a month earlier than weekly or every-three-week regime.

  • SweetHope
    SweetHope Member Posts: 439
    edited April 2015

    I wanted to further explain why I chose DD T for those readers that are still considering it. My MO, who has two board certifications told me the DD T was the most effective for my cancer (but the other two were still good options). Since I tolerated DD AC very well and T was usually easier, I was happy to try DD T. (I'm a champagne over Bud lite girl). And, the severe bone pain may be attributed to the Neulasta shot. It had caused the worst SE during AC and I thought changing from Claritin to Zyrtec was the answer. We will never know.

    Bottom line is everyone reacts differently, and you might breeze though a treatment that I could not tolerate.

    Best wishes to all on this difficult journey.

  • Trvler
    Trvler Member Posts: 3,159
    edited April 2015

    So you ladies didn't have issues on DD? I think it is fine if you choose it but unless there was a medical reason to do it, I don't know why a doctor would put anyone through it. I wonder if you do a weekly does and tolerate it well, you could switch to DD? I WANT it over but I am scared of SE's.

  • Supernannymom
    Supernannymom Member Posts: 50
    edited April 2015

    Hi All!

    Hi Kicks! I didn't have much morning sickness either (I have 4 kids) - but I get very motion sick as well as sick from anethesia, and my MO suspected I would have nausea issues because of that.

    Allison - what dosage taxol do you get? Weekly?

    I love reading about the taxol...my MO told me yesterday because I didn't have any issues with the Neulasta (my only ache that I noticed was a slighly sore back one morning) that DD Taxol may work just fine for me. My biggest issue and the one still facing me is the extreme nausea. They have decided to fill me with more IV meds during chemo and extra fluid (Thanks Bek!), and they are bringing me back in the next day for more IV meds and fluids.

    I am so fearful since my experience was so terrible, its hard to not get really stressed out. I lost about 9 pounds over the course of 8 days - I mean I am not a skinny girl so it certainly won't be a problem, but they way I lost it was miserable!!! I am back in the chair tomorrow- and will be so drugged up I probably won't be online for a few days. As soon as I am able I will check back in with my lovelies!!!

  • rleepac
    rleepac Member Posts: 755
    edited April 2015

    You can also ask about the Sancuso patch. It really helped me on #2 and #3.

  • Beachbum1023
    Beachbum1023 Member Posts: 1,417
    edited April 2015

    Hi Supernannymom, I had DD AC/T and finished 11/25. I struggled with the side effects the first round of AC, but I had it fairly under control after the first week. I was working 42 hours a week so I had to be able to do my job. I carried a lunch bag full of meds and OTC to fix any side effect that appeared. When I switched to DD Taxol I had Neulasta and the pain was horrible. The Claritin did not work and I switched to Tylenol #3 with Codeine. I had 3 Neulasta injections and refused the last full does. I only took half the dose to stop the pain. Since it was the last Taxol I didn't care, and I figured the blood counts would come up on their own.


    I was not given any other options for chemo. I had a large tumor, and the MO wanted to go with guns blazing. But I am left with a lot of side effects. I also have permanent heart damage from the Adriamycin. It is a uncommon side effect, but for me it is permanent. I have also packed on about 20 pounds from all of the meds, so I am reducing the meds now. I want to only take the heart meds, and nothing more.

  • Nightnurse
    Nightnurse Member Posts: 86
    edited April 2015

    Hi, Ladies! I just want to add my two cents! I had DD AC/T plus herceptin. I had a pretty easy time while I was getting it. However, I just want to warn everyone to pay close attention to your body down the road. i am almost 3 years past chemo and I have now been diagnosed with multiple heart conditions that are known to be caused by these types of chemo. I have my heart cath on Tuesday next week. Hopefully everyone will have an easy time. Just don't forget what these meds can cause down the road.

  • Supernannymom
    Supernannymom Member Posts: 50
    edited April 2015

    Hi Beach and Night- thank you for the insight! They changed my infusion med to a drug called Aloxi, and then they brought me in the next day for reglan and more hydration. I had my infusion on Thursday- and it kept the nausea under control until Sunday. On Sunday I was back on zofran and ativan. This was much better than the first round when I threw up for 5 hours and then had 9-10 days of nausea. I still have nausea but the zofran and ativan really help - which then leaves the lovely constipation. I don't really feel good until day 10 after infusion, and then on day 14 back to the infusion chair. Seriously the thought of infusion or a blood draw makes me nauseous...my MO said that it is really a "thing". I forget what she called it but when people have severe nausea, even the thought of chemo can insight nausea.

    I am fortunate, my MO had me go out on disability- which is good. I am a college professor - I can't imagine what I would tell students in my chemo induced fog!

    The neulasta hasn't bothered me too much - yesterday and today I have had an achy back -but that could change when I get to the taxol.

    Did those of you who have taxol - did you have it every week or every 2/3 weeks?

  • Leighrh
    Leighrh Member Posts: 317
    edited April 2015

    Does anyone besides me have trouble with the meds to handle the SE's.  It just seems like the meds I am taking, zophran, phengren, and the decadron are what bring me down the most.  I did have pretty bad nausea Thursday the day of my 2nd AC so started meds immediately and they kept me in a stupor for 5 days. I can't seem to read, watch tv or do anything really.  Stopped sterioids on Monday and tried to lay off nausea meds but it took me a day or more to wean off the effects of those... the dizziness and fogginess.  I haven't taken meds since Monday and today I am still foggy, can hardly read my phone.... I will address with MO tomorrow at my appointment but I am sure he will not have a solution.  He is the one after all who told me I would breeze through all this doing whatever I wanted.. young and healthy ... yada yada yada.... LIAR!!!  LOL I was young and healthy...after 2 rounds of AC I am a feeble old lady :(


     

  • Anonymous
    Anonymous Member Posts: 1,376
    edited April 2015

    Hi, I had AC dose-dense in 2011. I had to switch meds to promethezine to combat nausea. It was a drug I received for an unrelated surgery, and post-surgery I was super nauseated. Zofran did not work, neither did compazine or the others they typically give for chemo. I tried a left-over promethezine and it worked, and my MO wrote me a script for it. So you might give that a shot.

  • Supernannymom
    Supernannymom Member Posts: 50
    edited April 2015

    Leigh...ROTFL!!!!

    Yes I hear you - I am just now able to log in and post...my last round was on 4/16...they did give me a different drug, Aloxi, which seemed to help, but I am on zofran, ativan and then the steroids (steroids only for the first 3 days after treatment). I have compazine, but I haven't taken it - the zofran and ativan combination has worked for the breakthrough nausea this round.


    Leigh I feel like computer, TV, anything bothers me for the first 5-6 days. I am just now up and looking at the computer...I feel like a slug! My MO told me to get excercise every day...does getting up and taking a shower count!!! :-)

  • littleblueflowers
    littleblueflowers Member Posts: 2,000
    edited April 2015

    Leigh.....haha hahaha young and heAlthy! I think we must have the same MO. I feel like I'm a hundred after chemo. And I have the same issues with the SE meds. No idea what to do about it though, just wanted to say you are not alone!

  • Leighrh
    Leighrh Member Posts: 317
    edited April 2015


    Super-- Looks like we are on the same schedule... My 2nd round was on the 16th as well. Next go round is May 7th and I get nauseous thinking about it  :(  2 down and 2 to go... Seems like a daunting task today.....

  • Supernannymom
    Supernannymom Member Posts: 50
    edited April 2015

    Leigh...we will get through this...let's not think about the next round-and keep our nausea at bay (as I suck on a dissovable zofran!)

  • Trvler
    Trvler Member Posts: 3,159
    edited April 2015

    I am not on Taxol yet but I will be doing it weekly.

    Nice to see you Supernannymom. I am glad you are handing your nausea better and that you were able to get on disability.

    The only nausea med I didn't like was the compazine but I just didn't like how it made me drowsy and lying around for a while. I was also having gland pain that day which I don't know what is causing.

  • live_deliciously
    live_deliciously Member Posts: 346
    edited April 2015

    hi all. I've been posting on Feb chemo group and thought I'd chime in here. I'm on the dose dense regiment. Just finished a/c on April 7. had first dd taxol yesterday. I too hated a/c but it wasn't as bad as I thought it would be. Believe me it wasn't easy but it was great to mark it off the calendar and now all that phase is behind me. It really does go by fast . Taxol so far I feel better. I can eat and not feel nausea. Before just certain smells of food would trigger nausea. I still Need to do neulasta shot today so will see how I handle that with taxol And pray for no neurothopy or bone pain. Anyway im glad to be done with a/c . soon taxol will be done too. And Soon BC will be behind me ......

  • Trvler
    Trvler Member Posts: 3,159
    edited April 2015

    I was told no Neulasta with Taxol. Wonder why the difference?

  • Kicks
    Kicks Member Posts: 4,131
    edited April 2015

    My understanding as to why some do Neulasta on Taxol after A/C has to do with how your WBC did during A/C. At least that's what my Dr said. Orriginally be had said I might need it on Taxol also but by count stayed very high so he decided I didn't need it on Taxol but if it dropped, Neulasta would be added. My count stayed up well within normal throughout Taxol so never had Neulasta on Taxol.

    In other words, it's individual and how our body is responding. Different Drs also have differing opinions at times/on some things

  • live_deliciously
    live_deliciously Member Posts: 346
    edited April 2015

    i am on dose dense so I need the neulasta so I can get a heavy chemo dose every two weeks. Weekly taxol is less dosage and I was told that weekly is done with herceptin for her+ and no neulasta shot needed. Some people get it weekly some get every two and some every three. It depends on what type cancer you have.

  • Trvler
    Trvler Member Posts: 3,159
    edited April 2015

    Kicks: I was just there getting Neulasta and she told me the exact same thing you said.

  • melb44
    melb44 Member Posts: 130
    edited April 2015

    Hi everyone -

    After a bunch of soul searching and a second opinion I should be starting dose dense AC-T next week. It has been quite a journey to get here. I have chemo teach on Friday.

    Leigrh and Supernanny - I will be following in your footsteps. I have to admit that I am getting a bit nervous. I got the same young and healthy speech. I hope they can figure out how to help you. I had horrible morning sickness wit both my pregnancies. I hope that doesn't indicate anything.

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