Does joint stiffness/aching go away after Femara (Letrozole)?
Hi everyone,
Was wondering if those of you who have finished Femara (Letrozole) have experienced a return to "normal"? By normal, I mean did the joint stiffness and aching stop? If so, how long did it take after you stopped the medicine? I have been on Femara since June 2014 and am experiencing these common side effects. Still have many more years to go on this. Would like to know what others have experienced. Looking for a light at the end of this Femara tunnel. Thanks all.
Every8thwoman
Comments
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I probably won't be going off letrozole for some years but have a couple more months "under my belt" on it than you describe! The main stiffness I have is first thing in the morning with my hands & fingers (a little bit of a worry for a violinist) - it goes away once I flex and stretch. My main method for keeping aches at bay is to do water exercise three times a week. Many people like yoga or tai chi.
If your side effects are interfering with life and physical activity doesn't help, perhaps you could try a different aromatase inhibitor which might be better tolerated. My idea was to go to Aromasin (exemestane) next because it has a chemical structure distinct from the other two. It hasn't come to that so I have not changed however I'm happy that alternatives are available.
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Thank you vlnrph.
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Yes. I've been off letrozole for over a year now and the joint stiffness and achiness are back to normal (for a 58 year old!). I had severe joint aches and stiffness while on letrozole - the first couple of years were the worst, then they began to ease a bit after that, but never went away. The aches started easing a couple of months after I finished letrozole and were pretty much gone after 6 months. What a relief to be able to get up from a chair and actually walk away smoothly instead of lurching stiffly for the first few steps!
One thing I found that really helped with the stiffness and aches was exercise. Even walking every day for a half an hour or so really made a difference, and doing gentle yoga at least a couple of times a week helped a lot too.
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NatsFan, you have totally made my day! There is a light at the end of the tunnel!!!
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NatsFan,
Can I ask, how many years did you do the letrozole for, before finishing. I am now starting my 7th year of Femara, and I am hoping that all this pain, stiffness and arthrithis will go away when I finish. My bone density is really dropping now, so my Onc is considering me stopping Femara, and finishing with 3 years of tamoxifin.
thanks Ched
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Hi Ched - I did exactly 5 years and not a day more. At my last annual appt with my onc in July, we had a long talk about whether to extend past 5 years. She
said that the studies are still ongoing, and there have been no interim
reports issues showing any reason to go with 10 years of AIs as of now.I asked her
about the studies that show a benefit to staying on tamox for 10 years,
and why that wouldn't likely be true for AIs as well. She said not
necessarily. Her take on the matter was that tamox and AIs are both
strong effective meds, but AIs are stronger than tamox. She said given
that, it's not surprising that women who are on the weaker drug would
see a reduced recurrence rate if they stayed on it longer, but that
might not necessarily hold true for women who were on the stronger drug all along.I'm hoping that if the recommendation changes to stay on AIs for 10 years, by that time I'll be 10 years out and doing fine, so it won't apply to me anyway! I really hated being on letrozole.
I actually have my biannual DEXA next week. I always had plus T values until AIs, but now I have osteopenia. I'm really interested to see if my values have been improved since I've been off of it for over a year. I do a lot of exercise - running, weight training, yoga, hiking, etc., plus I take my Vit D and calcium, so hopefully the scan will show some increase in bone density, or at least that I've held steady.
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Dear NatsFan,
Hoping your DEXA scan shows improvement (or at least, no worsening of bone density). I had a normal DEXA scan a few months ago but I had only JUST begun taking letrozole. Am hoping there will be no loss of bone density 2 years down the road when I get the next scan as this side effect is a huge concern for many of us on this medicine. Sending good thoughts your way.
Every8th
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I am currently taking Femara and experience all of these pains. Specifically in fingers and hands and hips... I take Vitamin D and Osteo Nutrient Pro which was prescribed by the cancer treatment center of America in Tulsa. I have a DEXA scan on this Friday and am very worried about this... After receiving Stage IV mets to right breast and adrenal gland in Jan 14 to a clean PET in May I wonder about the effects of the Femara and whether the cancer will come back and attack my bones. I live every day with fear but hope at the same time. This test scares me so because other than the clear PET in May every test I have had since this all began in Dec 2012 has had a negative result. I guess that I am confused about what the DEXA scan will show.. Will it only show bone density or osteoporosis or will it show whether or not cancer has metastasized to my bones.? If any one could help I would greatly appreciate it. I feel so much anxiety and have had no appetite for the past couple of months. Ive lost about 10 pound in the last 6 weeks. I have no energy at all and my self esteem has suffered so greatly. I really want to stop worrying about cancer but have come to the realization that I wont be able to stop anytime soon. God bless you all. -
Oh, my! I haven't been on this site for a while now. I've been on Letrozole since January of 2013. Just got my results back from DEXA scan and results were not good. I believe my Onc will put me on some type of meds at my next visit. Is anyone on any now??
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TG - the dexa shows only bone density, and usually measures just a couple of points on the body. (Although it's possible to do a full-body dexa, that's not generally done for bone density.)
It would require a bone scan to show any metastasis in the bones - that's a completely different procedure. Even then, it's not definitive, as it shows areas of bone activity, so arthritis, any fractures that are still healing, etc., may light up. (Mine lit up where I'd had a fracture 4+ years previously, for example)
I'm sorry you're going through so much with this but don't worry too much about the dexa. It's quick, easy, painless and simply provides information on the state of your bone density. You and your team can use that to address any issues with density. Frankly, I'm rather surprised you weren't scheduled for one as a baseline prior to starting Femara.
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Went off in June-- like others, I found that regular exercise really minimized the joint issues--- and now I find that there are very few issues--- which is great!
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Just reporting back on my DEXA results - believe it or not, my density is now back to NORMAL!! No more osteopenia! I was totally stunned when I got the results - so much better than I could have ever hoped! It's nice to know that all my exercise, Vit D and calcium actually helped reverse the bone damage from letrozole. Woohoo!!!
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Thank you Hopeful I appreciate the information you gave me it is so hard going in for new test and not knowing what to expect I researched a little online but I guess I just didn't quite get it... Well at least I can hope for a positive outcome from this test. I just don't want to hear the words you have cancer here or there or anywhere again ... My life has been on repeat the past two years I would love to have a "normal Christmas" this year ... God bless and thank you again
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