Limiting carbs could reduce BC recurrence....

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cp418
cp418 Member Posts: 7,079
edited August 2014 in Clinical Trials, Research News, Podcasts, and Study Results


http://www.sciencedaily.com/releases/2014/06/140610122020.htm

Limiting carbs could reduce breast cancer recurrence in women with positive IGF1 receptor

Reducing carbohydrate intake could reduce the risk of breast cancer recurrence among women whose tumor tissue is positive for the IGF-1 receptor, researchers report. Using an unusual approach, this study assessed the combined association of two factors implicated in tumor growth -- carbohydrate intake and IGF1 receptor status -- to test whether activating the insulin/insulin-like growth-factor axis can impact breast cancer.

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  • Heidihill
    Heidihill Member Posts: 5,476
    edited June 2014

    And those individuals with Laron Syndrome (who have exceptionally low levels of IGF-1) are resistant to diabetes and cancer.

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  • mary625
    mary625 Member Posts: 1,056
    edited June 2014

    I guess we all have to assume we have IGF-1 receptors, because nobody I know of has been tested for them.  

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  • cp418
    cp418 Member Posts: 7,079
    edited June 2014

    older article -  Starch intake may influence risk for breast cancer recurrence, study suggests

    http://www.sciencedaily.com/releases/2011/12/111208184648.htm

    "The results show that it's not just overall carbohydrates, but particularly starch," said Jennifer A. Emond, M.S., a public health doctoral student at the University of California, San Diego. "Women who increased their starch intake over one year were at a much likelier risk for recurring."


     

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  • wallycat
    wallycat Member Posts: 3,227
    edited June 2014

    As a dietitian, I followed all the garbage that "science" said was right...low fat, high carb, etc.....

    and if I had to blame something, I would blame that diet.  Not only did I get early prediabetes, I got cancer; first one in my family.

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  • luv_gardening
    luv_gardening Member Posts: 1,393
    edited June 2014

    IGF-1 is more common in ILC than IDC according to several studies I googled. If I find a link in plain English I'll post it.

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  • april485
    april485 Member Posts: 3,257
    edited June 2014

    So, not only get rid of sugar in the diet, but no pasta or pizza either? Dairy, sugar, starch, red meat, soy. What is left? Sugarless gum of course! Oh wait, that has artificial ingredients in it. I know I sound annoyed, but I am at this point. No one knows what causes cancer or recurrence. It is a crap shoot. I have a friend who is vegan, exercises daily for at least 90 minutes and practices meditation and leads a low stress life. She breast fed both of her children and she had them at 23 and 24 . She grew up in a pristine clean air environment in the Adirondaks so no chemicals etc. Her family practiced organic gardening with no pesticides. No one in her family ever had any cancers that she knows of and most lived into their late 80's and beyond. She was diagnosed with Stage IIIc breast cancer last year. She is 44. What gives?

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  • DDOL
    DDOL Member Posts: 40
    edited June 2014

    April you are so right  no one knows why people get cancer !!! I've had cancer 4 different times already  they say it's in your family my 2 brothers are fine 😃 I have a lot of questions but no answers to why. I just started rad yesterday for BC. No one in my family has ever had BC so where do they said ( family )   Day by Day is what we say for them to fine a cure 

    Have a Bless Day April

    Diane 

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  • april485
    april485 Member Posts: 3,257
    edited June 2014

    I really didn't mean to be flip about this. I know that we need to eat healthy "most" of the time in order to make sure our immune systems are in tip top shape, but so many studies indicating correlation with this or that food or deodorant or whatever and it gets very confusing after a while.

    My MO told me to eat everything in moderation, drink a glass of wine once in a while (one) and not to put too much stock in these studies. I do agree that insulin spikes can't be good for us and could have a possible influence on diseases other than diabetes, but it seems so out of control to me regarding the "anti-cancer" way of life. I guess if it reduces worry and stress on someone to eat that way, it can be a good thing, but me? I need my bowl of whole wheat pasta a couple of times a week. I already kicked the meatballs to the curb in favor of marinara, but that is where it ends for me. Have a great day everyone!

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  • dlb823
    dlb823 Member Posts: 9,430
    edited July 2014

    I had posted another article here a couple of days ago about this research, not realizing it was already being discussed.  What's interesting and caught my attention in the link below that I don't think I saw in the Science Daily account of the research is this... "Among women with primary breast cancer that was IGFI receptor–positive, carbohydrate intake increased the risk of recurrence more than five-fold (HR, 5.5; 95 percent CI, 1.8 to 16.3)"   A five fold increase seems far more significant than more general nutrition advice to cut down on a particular type of food.  I was also extremely interested in Joy's information that IGF-1 is more prevalent in ILC (I had both IDC & ILC) and have had a metastatic recurrence in spite of extremely healthy eating.      Deanna

    http://www.oncologynurseadvisor.com/diet-may-impac...

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  • Fitzy
    Fitzy Member Posts: 136
    edited July 2014

    I went on a low carb diet from 12/20/12, lost 12 kgs and was feeling great, until I got dx with Liver Mets on 11/22/13! I'm ILC so go figure! I have also read that Keto diets can be bad for you, Ketones and lactate fuel tumour growth. I used to go in and out of keto, depending on my carb deprivation levels. 

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  • luv_gardening
    luv_gardening Member Posts: 1,393
    edited July 2014

    This an interesting study on the effects of diet on IGF-1 and Growth Hormones (GH).  Although it's about men's cancers, it also addresses women's cancer and includes data from the nurses health study.  

    For those who don't want to wade through this long piece, it says that the foods that raise IGF-1 are different in various studies so there may be other factors at work.  Basically milk, meat, other proteins and some minerals especially phosphorus (in meat and milk) and magnesium raise the blood levels.  A high carb diet or one which raises insulin will cause the liver to produce IGF-1, so raising blood levels. 

    Nutritional Predictors of Insulin-like Growth Factor I and Their Relationships to Cancer in Men

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  • robsp
    robsp Member Posts: 50
    edited August 2014

    Does anyone received some instructions about the current recommended daily intake of carbohydrates ? 

    I´m looking for some information about this subject and Wikipedia shows only 130 g/day


    Dietary Reference Intake

    http://en.wikipedia.org/wiki/Dietary_Reference_Int...

    Using a tool from usda.gov site where you fill your age, sex and weight shows that  I can eat 300g of carbs per day.

    Interactive DRI for Healthcare Professionals

    http://fnic.nal.usda.gov/fnic/interactiveDRI/


    I do not want to loose weight of make any fad diet. I just want to start a diet with current recommended daily intake of carbohydrates and I´m not sure where I can find a good resource about this subject.

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  • Lily55
    Lily55 Member Posts: 3,534
    edited August 2014

    A plant based diet is what was advised for me, and vegetables and fruit that are carbohydrates are fine as they have co factors that help healthy metabolism and dont create glucose spikes.  I was doing low carb for two years before diagnosis but was eating a lot of dairy. I no longer have cow dairy at all and found out it is casein protein in that which fuels breast cancer cells

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  • wallycat
    wallycat Member Posts: 3,227
    edited August 2014

    Lily, i would love to see the journal articles on the casein you mentioned.

    Interesting how different we all are.

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