Negative study on marijuana and BC

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This is a study from 2005 I ran across while doing research on the use of marijuana for breast cancer treatment. Don't want to rain on anybody's parade, but I thought I should post it. 

Delta-9-tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response

http://www.ncbi.nlm.nih.gov/pubmed/15749859

Comments

  • leggo
    leggo Member Posts: 3,293
    edited March 2014

    http://www.ncbi.nlm.nih.gov/pubmed/15749859


    Falleaves, hope you don't mind, but I made your link hot. I think it's important that we have ALL the info. You're not raining on anyone's parade. 

    There are also many studies contradicting this. Don't have time to post them alll, but everyone's ability to google is as good as anyone elses.


  • leggo
    leggo Member Posts: 3,293
    edited March 2014

    That last line wasn't a dig at you, just my way of dismissing the "crew" that blow in when they're bored. I could make time, but I won't...at least not to satisfy them. Just wanted to clarify because it sounded like I was being pissy to you and that is so not the case.

  • Fallleaves
    Fallleaves Member Posts: 806
    edited March 2014

    I don't know why my links are cold sometimes...and no offense taken, Leggo.  Anyway, I was really surprised by this study. Really everything else I've been finding about cannabinoids has been opposite of this. But I figured if I'm going to post positive articles (which I generally do) I should post negative ones, too. Of course, anomalous studies pop up now and then with everything. It really makes sense to judge things based on the whole body of evidence.

  • leggo
    leggo Member Posts: 3,293
    edited March 2014

    It seems there are as many negative articles as positive ones. All I can garner from any of them is that it might be cancer-type specific. Hopefully, at some point, which ones becomes clear. In the meantime, I'll be the guinea pig. Thanks for posting that link.

  • twinkly
    twinkly Member Posts: 182
    edited March 2014

     Thanks for posting that Fallleaves....it really is important we don't wear blinders in our research.  And to demonstrate what leggo said about there being so many articles out there, there was a recent article from the Huffington Post, in 2012

    http://www.huffingtonpost.com/2012/09/19/marijuana-and-cancer_n_1898208.html

    ....and here is a blurb from the article....

    A pair of scientists at California Pacific Medical Center in San
    Francisco has found that a compound derived from marijuana could stop
    metastasis in many kinds of aggressive cancer, potentially altering the
    fatality of the disease forever.

    "It took us about 20 years of research to figure this out, but we are very excited," said Pierre Desprez, one of the scientists behind the discovery, to The Huffington Post. "We want to get started with trials as soon as possible."

    The Daily Beast first reported
    on the finding, which has already undergone both laboratory and animal
    testing, and is awaiting permission for clinical trials in humans.

    Desprez, a molecular biologist, spent decades studying ID-1, the gene
    that causes cancer to spread. Meanwhile, fellow researcher Sean McAllister
    was studying the effects of Cannabidiol, or CBD, a non-toxic,
    non-psychoactive chemical compound found in the cannabis plant. Finally,
    the pair collaborated, combining CBD and cells containing high levels
    of ID-1 in a petri dish.

    "What we found was that his Cannabidiol could essentially 'turn off'
    the ID-1," Desprez told HuffPost. The cells stopped spreading and
    returned to normal.

    "We likely would not have found this on our own," he added. "That's why collaboration is so essential to scientific discovery."

  • abigail48
    abigail48 Member Posts: 1,699
    edited March 2014

    I don't think it would be because it suppresses the" anti tumor response", but because it's strongly estrogenic.  it's said that with strong use men's breasts grow 

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