Her2+ Vaccine Trial?

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CameraKim
CameraKim Member Posts: 81
edited June 2014 in HER2+ (Positive) Breast Cancer

Hello Ladies :)

Just wondering if anyone out there has been in a vaccine clinical trial? I just finished up my Herceptin two weeks ago and my doctor has but me in touch with a team at MD Anderson that are doing a study on a vaccine for those of us diagnosed with Her2+++ .

  1. disease recurrence rates between HLA-A2-positive patients receiving the GP2 + GM-CSF vaccine and HLA-A2-positive patients receiving GM-CSF alone

Wondered if anyone on here has participated in the trial.

I'll have to fly from Portland, Oregon to Houston once a month for the inoculations….that is going to be costly, but I'm thinking it's worth a try! I'll go every four weeks for 6 shots and then two boosters a year for the next three years. I'm so hopeful that some of these new vaccines they're studying will be effective!

Would love to hear from others that have participated!

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  • Girlstrong
    Girlstrong Member Posts: 438
    edited December 2013


    Hi CameraKim:  I have heard about this trial but am not on it.  Hopefully when I am done with my active treatment the trial will still be accepting patients....please keep us posted as to how the injections go etc.  I would love to learn from you and others on this topic.  By the way...congrats on being done with your active treatment.  What a great Christmas present.  Keep the faith!!

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  • Momof2inME
    Momof2inME Member Posts: 683
    edited December 2013

    I am in this trial.

    Here is the link to a thread on here about the trial.

    Good luck!!!

    http://community.breastcancer.org/forum/67/topic/794166?page=5#idx_148

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  • tatasister10
    tatasister10 Member Posts: 52
    edited December 2013

    HI, yes I was diagnosed in 2011 with stage 1 er+ pr+ and her2+ I found the clinical trial online and started it in July 2013. I had to go every three weeks for my injections to winston salem NC. That site and a couple others have closed because they will be starting the 3rd phase of the trial sometime next year...(the 3rd phase is given WITH herceptin) It was very tolerable and each injection left me with a quarter or so sized lump on my leg (which is normal and goes away after 2-3 days) Its very itchy and looks like a really large mosquito bite. I had no side effects whatsoever aside from wanting to itch my leg off sometimes. Make sure you find a site soon, because all of the phase 2 locations will be closing soon from what I understand. If you have to fly to MD anderson, threre is a company called corperate angels that might be able to help. Its for cancer patients. Let me know if you have anymore questions. 

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  • BlueFox
    BlueFox Member Posts: 99
    edited December 2013

    Hi,  I am interested in this.  I am finishing Herceptin at the end of January.  

    There are 2 centres in Europe (Germany and Greece) - does anyone know if they still be open for recruiting next year?  Does one have to be a US national to participate?

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  • Girlstrong
    Girlstrong Member Posts: 438
    edited December 2013

      Hi BlueFox: I have attached the link that describes the study and also gives participant inclusion criteria and locations of the study.  Hope this helps.   


    http://clinicaltrials.gov/ct2/show/NCT00524277

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  • dancermom
    dancermom Member Posts: 53
    edited December 2013

    I just got the first inoculation after the six months after the initial series of inoculations.  I am going to Baltimore.

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  • BlueFox
    BlueFox Member Posts: 99
    edited December 2013

    Thanks Girlstrong.  I've now emailed the two centres in Europe.  The German centre isn't recruiting anymore and they only deal with military.  I'm still waiting for a reply from the Greek centre.

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  • CameraKim
    CameraKim Member Posts: 81
    edited December 2013

    Hi Ladies, we were all set to go down Monday to meet with the Doctor at MDACC....airline tickets and everything. Apparently we were misinformed about what our insurance  covered and it looks like I won't be able to take part....DARN! The study sounded so promising with little/no toxicity.

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  • Toastiecat
    Toastiecat Member Posts: 132
    edited January 2014

    Hi,

    Just wanted to chime in here because I'm starting this trial at Sibley Memorial in DC on Monday. A little nervous, but excited!

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  • soriya123
    soriya123 Member Posts: 662
    edited January 2014

    Toattiecat, keep us posted!!! Let us how you doing in the trial.  :)

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  • CameraKim
    CameraKim Member Posts: 81
    edited January 2014

    Good luck Toattiecat! My trial closed on the 31st and I missed it. Long story but couldn't get insurance company okay, but found a loop hole just today and it looks like I could have done it after all. So hopeful that this new vaccine therapy works....exciting stuff!

    Best of luck to you. I hope you'll check in and let us know how you're doing!

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