Ki-67 95%

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  • Isiniita
    Isiniita Member Posts: 1
    edited October 2013


    Hi sisters,


    My KI-67 is 90% (both in needle biopsy and in tissues from the surgery) and the first three chemo treatments (TX) didn't work at all and in the meanwhile the tumour grew and cancer got into 9 of my lymph nodes. Which kind of sucks. Would've been nice to skip taking those drugs. But I've asked them to give me the roughest treatments available from the start and I bet I'll get them now - fingers crossed that they work!


    I'm 31 years old and would love to at least get my first wrinkles before I die. Making sure to enjoy every single day until then though! And it's not about the number of days but about how you spend them, right? :)

  • Josiekat
    Josiekat Member Posts: 85
    edited October 2013


    I remember sitting in my car, sobbing. My surgeon had said, "30 is high for KI-67 and you are 98"


    I was sure I was not going to make it a year.


    I am now almost 2 years out and feeling great.


    Numbers are just numbers. No one knows your fate.


    Xoxoxo

  • FairyDogMother
    FairyDogMother Member Posts: 253
    edited November 2013


    When I got my pathology report from the biopsy doctor I needed a decoder ring to understand it. I was a scientist and did genetics. When I figured out what the KI-67 meant I flipped the computer off and walked around the block. My oncologist surgeon said anything above 30% is considered aggressive. That explains why my Felix (the name I call my cancer tumor) grew over 1 cm from time of biopsy to surgery. Mine isn't has high as 98% but it went from 63-67% in a month. Thanks to the KI-67 I WILL BE FORCED to do chemotherapy. Thank you to all of your sharing your journey.

  • Annie54
    Annie54 Member Posts: 247
    edited November 2013


    So you do not have to do chemo because of your KI-67 results? If 67% is high, why not chemo? Curious because my KI-67% was similar to yours.

  • FairyDogMother
    FairyDogMother Member Posts: 253
    edited November 2013


    Annie54- That was a typo. The oncotopye text said no chemo, but my mammaprint said Chemo because of my Ki-67. It took that into account. I start chemo, Wed. Nov 20th.

  • Annie54
    Annie54 Member Posts: 247
    edited November 2013


    Ok good...I thought I had missed something! Good luck with your chemo. I had 6x TCH this summer and although it was no walk in the park, it wasn't horrible either (for me). I worked all the way through - and just finished radiation a couple of weeks ago. Just plow ahead and you'll be through all the tough stuff before you know it! There is a light at the end of the tunnel!


    Annie

  • FairyDogMother
    FairyDogMother Member Posts: 253
    edited November 2013


    Thank you Annie54. As Wednesday gets closer I’m getting more nervous. I wonder what I should eat for breakfast.

  • Annie54
    Annie54 Member Posts: 247
    edited November 2013


    Eat what you like....my first treatment I took lots of snacks and drinks only to find out that they had food and drink to offer me! I came to think of treatment as my "spa day" as I would sit in a heated recliner, watch tv, take a nap and/or watch netflex on my computer. The nurses would bring me soup and sandwich or drinks. No one at work or home bothering me! The actual treatment is painless but the benadryl they give you does make you foggy for awhile. The real SE's don't kick in for a day or two. Good luck tomorrow - don't be scared...you will do fine.


    Annie

  • joeysma
    joeysma Member Posts: 1
    edited June 2014

    Just finished 6 months of chemo...had a biopsy done a few days ago and it shows many dead cells (horray!__ but it also shows the ki67 has gone up to 95.  Im scared! what can i expect?

  • ynwa0011
    ynwa0011 Member Posts: 4
    edited December 2014

    my mom has the same diagnose like yours..good helps u i hope much

  • Mimima
    Mimima Member Posts: 1
    edited May 2017

    I haven't seen any post since 2013. This is my concern in my recent diagnosis and Ki - 67 score of 95% scared the hell out of me! Thank you all for your magnificent posts that made me understand it better. I am not going to focus on that number but just on getting well :-). It would be nice if anyone has anything else to add. thank you

  • Moderators
    Moderators Member Posts: 25,912
    edited May 2017

    Hi Mimima,

    Welcome to the boards!

    Hopefully members will add to this thread to share their knowledge with you.

    If not though, you can create a new topic altogether in this forum to get a new discussion going.

    Warm wishes,

    The Mods.

  • gb2115
    gb2115 Member Posts: 1,894
    edited May 2017

    hi Mimima--mine was high too, and although both oncologists mentioned it they explained why they don't base the plan of care on it. Everything for me pretty much came down to the genomic testing results.

  • Blair2
    Blair2 Member Posts: 495
    edited October 2017

    Hello to any recent members who might be waiting so anxiously to have surgery to determine if they need chemotherapy treatments. My surgery is coming up mid Oct. and I've lost 5 lbs. already worrying over this mess. My Ki-67 is sitting at 60%. So, does this mean I have an aggressive cancer that has most likely spread? My breast surgeon's office doesn't like answering simple questions without pay, so I too have had to rely on my own research. The plan is to definitely treat me with radiation after a lumpectomy, with reduction of both breasts, and on top of this I have heart disease that makes radiation and chemo a very bad risk to my already beat up heart. The tumor is on my left breast too! I'm 68, IDC, Stage 1, Grade 2. ER+, Pr +, but HER2 negative. My cardiologist just gave the ok for surgery, but it's the treatments I may need that bother me the most. I really care about my heart more than I do my breasts. (If younger I'd feel different about my breasts). Mastectomy is out of question to the breast surgeon. Even my cardiologist said there's some risk to the heart, but the cancer has to be attacked. I suppose from what I can understand that whether or not I will need chemo, will depend more on whether the cancer has spread to nodes or if the Oncotype DX test score is high - more so than the Ki-67 result, but it sounds like it has a good chance of spreading if that Ki-67 is high. I think the Oncotype DX test seems more of a predictor of reoccurrence along with aggressiveness of the tumor than does the number or percentage of Ki-67. It's so confusing and it's not explained anywhere in detail as to what my chances are with it most likely spreading due to the Ki-67. Kill the heart or kill the cancer - great prognosis. Will talk to oncologist soon. I'll post what they mightsay later.

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