cholesterol metabolism fuels estrogen receptor breast cancer

Interesting, thanks for posting.

Cholesterol caught my eye & I read both articles .interesting to me as was just at my final onc follow-up & happened to get a new-to-me-onc who mostly does research but does do follow-up clinics to help the overflow....so, my chance to talk with a researcher! I'd come with the question, so do I go off arimidex and i understand there is controversy and........she said there is no controversy. there is nothing that tells us that 10 yrs is better than 5. In fact, the AIs have their long-term ses such as heart things, osteoporosis..cholesterol........ and she gets more concerned with those. But I'm fat! around the middle! I said, and estrogen is produced by fat! so, she said, maybe you'll get more limber (except for the arthritis) and can exercise! (fat chance I thought but just said hm..........) but, she did plant a thought seed in me......oh, yes, maybe.

I had not walked much in years because of very painful deformity in foot that felt like I was holding a stone between 2 toes. got that surgeried 2 yrs ago. took time to be able to walk properly, but now i can, but arimidex had me so friggin stiff there were times I thought I'd have to go to tamoxifen......my 5 yrs up in jan - have a bonfire of the arimidex packaging, she suggested, for New years party, but don't burn & inhale pills they might be toxic lol. so, yes, I think I've been prompted to change my outlook & behaviour....so wish I lived in near tropical waters would gladly swim every day.

I was also excited about this news. It fills in a huge gap.

Sulphoraphane (from Broccoli and Co.) also lowers cholesterol.

Rdrunner, if your cholesterol is fine, why does he want you on crestor?

I got the "get on aspirin and anticholesterol meds" message from my onc in July. He said, "if your internist should see fit to do so." Simvastatin is the one the most people are using, but my internist chose Crestor which I think is not the same and is still under patent.

I've recently read what Momine described in regards to elevated HDL levels - some breast cancer link there.  My concern with the statins is they lower LDL and may increase HDL which is already elevated over 100.  Frustrating because taking Femara have caused my cholesterol levels to increase.....  Now what - take more drugs?

http://www.ncbi.nlm.nih.gov/pubmed/23833125

http://www.fhcrc.org/en/news/spotlight/imports/long-term-use-of-statins-and-postmenopausal-breast-cancer-risk--.html

Momine - I hear you.  I'm very frustrated as I only eat poultry, seafood, lots of salads, minimal cheese and eggs - daily cereal for fiber/fruit.  Mine has now reached total 239 and I am fighting to stay off statins.  HDL 112.  The LDL keeps creeaping up.....  Exercise - daily long brisk walks and outside barn chores 7 days/wk plus riding with good weather.  I'm convinced it is genetic condition as I understand we take in 20% of our dietary cholesterol and 80% is our own metabalism.  I need to find something other than statins and red yeast to help me.

No magic number.

http://www.cbsnews.com/8301-33816_162-57612669/morning-rounds-when-should-doctors-prescribe-statins-for-cholesterol/

Momine - I just happened across that article yesterday and now it looks like it will be all over the news.  So confusing for patients......

http://www.medpagetoday.com/Cardiology/Prevention/42958?xid=nl_mpt_DHE_2013-11-18&utm_content=&utm_medium=email&utm_campaign=DailyHeadlines&utm_source=WC&eun=g376694d0r&userid=376694&email=jlong@i-review.com&mu_id=5369993