question about Neulasta

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From what I understand I get the Neulasta 24hrs after chemo.  Have had several people tell me it is worse than the chemo itself, so it scares the crap out of me.  My problem is I am allergic to acetaminophen and NSAIDs so my option for pain killers are usually some form of opiate :(  I have rheumatoid arthritis so I'm used to joint pain but I am told this pain is intense.  Just looking for those who have gone through it.

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  • MizMarie
    MizMarie Member Posts: 332
    edited June 2013

    Hi Scribblinhanna,

    I had no real problem with Neulasta; only some mild leg pain, which reminded me of "growing pains" I had when I was a child.  I didn't have Neulasta after my first chemo (it isn't automatically given at my tx center), and ended up in the hospital very sick with neutropenia  - THAT was scary.  Good luck!

  • Pessa
    Pessa Member Posts: 519
    edited June 2013

    Had 4 Neulasta shots in total.  No problems.  Had mild lower back pain after the first shot.  Nothing after that.

    I did take Claritin (one pill before each shot) at the advice of the Oncologist.  It prevents many of the side effects.  Several other aquaintenances of mine were told the same thing by their MOs so it wasn't must mine.

  • SelenaWolf
    SelenaWolf Member Posts: 1,724
    edited June 2013

    I struggled with the Neulasta - it seemed to greatly intensify my arthritic pain - however, it was manageable with warm baths and heat.  Aspirin, acetaminophen, ibuprofen didn't affect the aching bones/muscles; only heat seemed to soothe.

  • ruthbru
    ruthbru Member Posts: 57,235
    edited June 2013

    Make sure it's Claritan, not Claritan D. I had four Neulasta shots. No problems (and I am allergic to all kinds of medications too). I wouldn't have wanted to do chemo without Neulasta. I was glad I didn't have to worry nadirs, having to avoid people because germs, having to have chemo postponed because of bad blood work etc. etc..

  • hrf
    hrf Member Posts: 3,225
    edited June 2013

    Like Pessa, I found Claritin to be very helpful with the Neulasta pain. Learned that from the ladies on this board. I took it the day before the shot and for a few days after. Solved the problem. I had also found the Neulasta pain to be very bad so appreciated the Claritin.

  • encyclias
    encyclias Member Posts: 302
    edited June 2013

    scribblinhanna, I had two Neulasta shots during my A/C chemo when my white cell count dropped below the normal range.  Never noticed any pain, or anything different at all.  I guess we are all individuals as to how we react to various drugs.  You may have no pain whatsoever from Neulasta.

  • Maureen1
    Maureen1 Member Posts: 614
    edited June 2013

    I had 8 shots of Neulasta - one every 2 weeks 24 hours after chemo and only had some mild low back pain with a couple of the shots and some mild aches in my thigh with a couple of the shots so I didn't need to take anything for the pain. Everyone is different but my blood counts dropped really low with chemo and it was during flu season so I couldn't have done chemo without it...it was worth it, I never got an infection or flu bug. Good luck...hang in there:)

  • scribblinhanna
    scribblinhanna Member Posts: 32
    edited June 2013

    Thank you everyone :)  I will try the Claritin too.  I have had heard so many horror stories from it that it scared me.  I am hoping to be one of those whose effects are mild so I can enjoy 4th of July festivities with my boys :)    

  • jbdayton
    jbdayton Member Posts: 700
    edited June 2013

    I had severe bone pain after the first 2 Neulasta shots.  I was taking Claritin on the day of my shot and 2 days after.  For round 3, and thereafter, my MO had me change to taking the Claritin 2 days prior to chemo and continue for 10 days.  Never had any more pain.  My white blood cell counts never got below the bottom range of normal. 

  • Claire_in_Seattle
    Claire_in_Seattle Member Posts: 4,570
    edited June 2013

    Some pain and additional dragging, but that was it.  I did 12 shots as had 12 rounds of chemo (AC+T).

    I was able to give myself the shots which made everything much easier.

    I would do the Neulasta again even if not required (was part of the chemo study I participated in).  It was wonderful not to have to worry about infection, whether OK to eat runny eggs or pink steak, when I sliced my thumb instead of the potatoes, and other mishaps.  Plus I could eat raw fruits and veggies.

    I never got sick and all went OK with chemo.  That was really worth the extra precaution. - Claire

  • Judieheyjude
    Judieheyjude Member Posts: 4
    edited June 2013

    I have heard that taking Claritin on the days of the Neulasta shot and 2 days after helps get you through the bone and muscular pain.  Can someone respond to this?

  • midwestdoglover
    midwestdoglover Member Posts: 23
    edited July 2013

    Hi Scribblin!

    Yes , something to worry about, for those of us that have autoimmune disease. I have RA/Lupus for a long time.   For 2 yrs, i did Remicade, so used to IV's every 6 weeks. Had a allergic reaction to that one, as well as chemo and the port.  They always pre-medicated with IV Benadryl and steroids, prior to Remicade infusion.....which helped the little bit of psoriasis i have. They do the same now for my chemo...so it's like 4 bags pre-drips IV, 2 anti-nausea meds also

    I never was an allergy person, but this has been the worst allergy spring season, hi mold, grass pollen , etc.....all the spring rain.  Unless this is something i developed from chemo, or with age. So every day i take or tried, Zyrtec, Claritin, Allegra ( all generic now)...And still need oral Benadryl, and nasal mist.  So i welcomed Benadryl IV, since allergic reaction while getting chemo.

    I never noticed joint pain from Nuelasta, and you are right we are used to joint pain, and it's not just and old persons disease, RA./ especially hard on the JRA, little kids getting RA

    I am able to continue my methotrexate, 6 pills a week, 2 celebrex a day,  and Plaquinel, but not biologics, so that helps the joint pain.  I wish Aleeve would help, but doesn't, and NSAID Relafen, is cheap, but darn it Celebrex is working better, but the cost is horrible. I ask for samples, if they have any. 

    I just graduated by a/c chemo, going to start Taxotere July 17th, i might still need the Nuelasta, we shall see

    First chemo, my WBC dropped to a 1, it was a 3  yesterday, and i haven't needed a hydration IV, electrolites were really good, i eat ice cream, !Cool

    Take care , keep in touch, to talk about the RA and BC

  • slickchickie17
    slickchickie17 Member Posts: 125
    edited July 2013

    I had 7 neulasta shots & didn't experience any bone pain until I began taxol. I took claritin throughout chemo bc it was recommended to help lessen bone pain associated w/neulasta. It was allergy season, so I just took 1 pill each day. I had quite a bit of pain w/taxol & opted not to have my 8th neulasta just in case it was contributing to the problem. The benefits of neulasta tend to outweigh the risks, but of course that isn't true for everyone!

  • encyclias
    encyclias Member Posts: 302
    edited July 2013

    MidwestDogLover, I never had any pain from the two Neulasta shots I was given.  At the time, I was taking A/C chemo, neither of which drug generally gives joint or bone pain.

    As an aside and which is often not even noticed, is that along with your head hair, eyebrows and eyelashes, most chemo patients lose the hair in their nose -- hair which normally blocks much of the pollen, mold, dust, germs, etc., that we inhale.  Could that have something to do with your worsened allergy season?

    Carol

  • midwestdoglover
    midwestdoglover Member Posts: 23
    edited July 2013

    Carol, Your a genius!....i never thought of that. I know, the allergy counts have been off the charts this year here.   You just know i had to look in the mirror....Maybe some deep inside left, i dunno?....The PCP could look with his flashlight!

    I have a polyp in my sinus on one side, i will have to get it out one year. Unless surgery got modern am sure, but i hear your face gets a little blue under the sinus area....LOL

    Just graduated from A/C, the big 4, i still have a 1/2 of eyebrow left, very thin on each eye. And i was surprised a little eyelashes left, just a little, cause i tried mascara, Lancome goes on think...ha!

    Didn't shave my head yet, still have teeny long gray fuzzy hairs, around the bang area, and sides, but the back of head is gone, after 2 weeks!  And the very back of head, by neck has 1/2 inch dark hair. I'm washing my head just once a week.   But i guess hair will grow back on radiation?....8 weeks  of Taxotere starting 7/17.....and they got me down for wkly labs!......Just needed hydration once, but i passed out, allergic they have deducted, to the numbing spray maybe. So they watch me like a hawk, and luckily i get the same nurse, and she is on vacation now, she will be back i hope by the 17th...They got 3 nurses watching me, if my port flips again, or if i get hives again

    I am going to call the surgeons office Monday, if they are there!..My SIL had a mastectomy and port in arm, she had a choice, and they gave her local anesthesia, no operating room.  I'm going to cal them back, they left a msge with date, the 12 th to sew port down.  If they can give me local anesthesia, or twilight sleep, of course i had a reaction to port surgery!....When anesthesiologists, and surgeon left, the docs on call didnt get msges.  I turned blue!....SO we got that figured out, stopped BENICAR, BP med, it makes my BP drop too fast....

    Argh, too many weird things happening!, trying to laff at them now!....I can take it, with  some pain meds shot in the arm...he is just sewing port down, and gotta reopen it....should be fastYell

    Sorry this post is so loooong, needed to VENT

  • dltnhm
    dltnhm Member Posts: 873
    edited July 2013

    I didn't have any side-effects of pain with this shot. (AND I self-administered it. No need to make a special trip to the doc.)

    Some guys and gals take Claritin before, the day of, and a day or two after. I passed on that as well.



    We are all so different - but try not to be scared. Lots of people do just fine with chemo and the other meds. You are going to find more of the problems here because those who have trouble come seeking help.



    Hoping for no or little side-effects for you.



    Whatever you choose - keep moving daily and drink lots of water daily - no matter what. The activity and the hydration make a huge difference.





  • GrammyR
    GrammyR Member Posts: 702
    edited July 2013

    Everyone is different. For me it WAS worse than the chemo and lasted for about 4 days after each of 8 rounds of chemo. I took Vicodin and then Percocet ( was allergic to that one I discovered) I still screamed out in pain for many days alone while my fiance was at work) My WBC also fell to 0 every time and was hospitalized one time for fever 101F. On the other hand I had a co-worker who never once complained of pain. She was such a godly person her belief was so strong. Well since mine I have returned to god and find it so much comfort. It can be a very different experience for many. Just accept the prayers and good wishes as I am sending you. It too shall pass. Oh and I will add I did not become addicted either. Pain meds were created to help real pain so do not be afraid.

  • GrammyR
    GrammyR Member Posts: 702
    edited July 2013

    Everyone is different. For me it WAS worse than the chemo and lasted for about 4 days after each of 8 rounds of chemo. I took Vicodin and then Percocet ( was allergic to that one I discovered) I still screamed out in pain for many days alone while my fiance was at work) My WBC also fell to 0 every time and was hospitalized one time for fever 101F. On the other hand I had a co-worker who never once complained of pain. She was such a godly person her belief was so strong. Well since mine I have returned to god and find it so much comfort. It can be a very different experience for many. Just accept the prayers and good wishes as I am sending you. It too shall pass. Oh and I will add I did not become addicted either. Pain meds were created to help real pain so do not be afraid.

  • Anonymous
    Anonymous Member Posts: 1,376
    edited August 2013

    I had 8 injections of Neulasta -- didn't have any side effects at all, at least not that I would attribute to that. All my problems were likely due to the chemo itself. However, I was taking Claritin daily anyway, for my year-round allergies. Who knew that it might have prevented any problems from Neulasta? (Nobody ever mentioned Claritin to me for possible Neulasta side effects back then.) Just happenstance......

    The only bone pain I had was on Taxol -- I was really glad when that was done!

  • Moderators
    Moderators Member Posts: 25,912
    edited August 2013

    In the info about Neulasta at the main Breastcancer.org site there is this explanation about why Claritin is sometimes used: "Your doctor may prescribe a non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen or naproxen to treat bone pain caused by Neulasta. Neulasta helps the body make more white blood cells by stimulating the immune system, which also creates histamines. So your doctor also may recommend an antihistamine such as Claritin (chemical name: loratadine) – NOT Claritin-D – to ease bone pain caused by Neulasta."

    • The Mods

  • SpecialK
    SpecialK Member Posts: 16,486
    edited August 2013

    I think many oncologists do not volunteer the information about Claritin and Neulasta bone pain because the information is still currently anecdotal.  I asked my onc if I could take it and he said I could if I wanted to.  I think many who take it on this site do so because they found out about it here.  If anyone's oncologist is reluctant here are the studies:

    http://clinicaltrials.gov/show/NCT01311336

    http://clinicaltrials.gov/show/NCT01712009

  • gavinsgrandma
    gavinsgrandma Member Posts: 407
    edited August 2013

    I had my first infusion last Thursday and really did not feel that bad after the chemo, but about 10 minutes after the Neulasta shot I stared to fade. By midnight day after shot my shingles( which I have had for years and they break out at the base of my spine) where so painful I ended up in the ER for pain control that morning. I am not new to shingles but I am new to chemo and Neulasta so I am going to see my PCP and MO this week and find out how high I can go on the anti-virals , I think had it not been for the shingles the pain would not have been as bad and I did not take Claritin, wondering if I should for round 2? It is not part of MO protocol but he ok'd it if I wanted to.



    Shary🌞

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