Red Devil

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Hi Everyone,

I am 4 down, 8 to go on Abraxane.   I'm doing okay on that one - no real serious side effects - the worst has been the awful persistent sore throat.   My oncologist is having me stay on Claritin D to get rid of the drainage.

When I am done with Abraxane, I have 4 treatments of the Red Devil - once every 3 weeks. 

I would like to know how you handled the Red Devil.   How was it the day of and the days following?   How many days 'till you leveled out until the next treatment?   

My oncologist is very proactive on side effects and has said I will be taking several different anti-nausea meds to ward off the nausea.

I would just like to hear from you all as to how it affected you personally.

Thanks so much,

Melissa  Laughing

Comments

  • golf1234
    golf1234 Member Posts: 1
    edited June 2013

    I finished 4 treatments of the Red Devil.  The first treatment was the worst, felt like I was motion sick after leaving the clinic.  Then, had some nausea the next day - not horrible, more like morning sickness.   The last 3 treatments, I've really had no side effects.  The neulasta shot kicks me in the butt.  Really tired and achy the day after getting that.  I also get several anti nausea meds with each treatment.

    Good luck!

  • max2111
    max2111 Member Posts: 17
    edited June 2013

    I have looked in my notes and see that the Red Devil combo I am taking is:

    • 5FU, Epirubicin, & Cytoxan

    I have seen others take Adriamycin instead of Epirubicin.   Are those two the same?

    Thanks so much to everyone....

    Melissa  Cool

  • Sassa
    Sassa Member Posts: 1,588
    edited June 2013

    I had 4AC.  The nausea (and the all night vomiting after the second dose) was my worst side effect.  I was put on progressively stronger antiemetics until I was on Kytril (ganisetron) and I knew if I had a fifth treatment, I would have been vomiting again.

    The adriamycin is extremely irritating to the bladder and has apotential side effect of bladder cancer, so you need to pee it out as fast as possible. Start with water as soon as you get up, drink water on the way to chemo, and keep drinking water during the infusion, and afterwards. 

    When the urine no longer has a red tint (that is why the drug is dyed red), you are home free. I would start passing the red out while I was still being infused.

  • NancyHB
    NancyHB Member Posts: 1,512
    edited June 2013

    I too had 4xAC.  Never had one bit of nausea or vomiting (I was terrified of that)!  The steroids kept me feeling pretty good for the three days after treatment (which was Thursday).  Monday morning, tho, I felt like I'd been hit by a truck (like a bad case of the flu; aches, pains, skin hurt like I had a fever, etc.)  It got better from there, and usually by Friday or Saturday I was feeling much better.  Every treatment, tho, recovery was a little longer - took me the full two weeks between treatments to recover from the fourth one.  It was hard, but manageable. 

  • ruthbru
    ruthbru Member Posts: 57,235
    edited June 2013

    AC. Like someone else said; drink, drink, drink fluids before during & after infusions. Take your anti-nausea medications exactly as ordered. I never threw up but felt like I had a slight case of the flu the whole time. That being said, I worked full time throughout my 4 rounds (dose dense with Neulasta shots), did everything I had to and most of the things I wanted to do too. I felt worst of the first three days after, and then gradually better, the second week I felt pretty good. Try to get a little exercise if you can at all. Eat whatever you can stand (strangely, I craved mashed potatoes and Mexican food....the hotter the better!). Chocolate tasted like chalk, so that kept me from gaining alot of weight! Also strangely, I didn't feel tired but instead I felt all hyped up (like an ADHD kid without her pills!) and gittery....maybe it was the steriods? One tip I got was to keep my nails (fingers & toes) polished to keep them strong and protected. I don't know if that advice has any basis in fact, but I did it and the nails came out OK. Not a fun time, but you can get through it. Best of Luck! Ruth

  • Sassa
    Sassa Member Posts: 1,588
    edited June 2013

    Like Nancy HB, I also took longer between each  treatments to bounce back.  The first one I was OK about a day later.  By round 4, it was two weeks before I felt normal.

  • Rebok65
    Rebok65 Member Posts: 4
    edited July 2013

    I had 4 cycles of the AC too, every other week.  I feel that I was blessed and very lucky with it because I didn't have any nausea at all.  The oncologist gave me a large infusion of anti-nausea meds each cycle.  Plus they gave me plenty of anti-nausea meds to take at home too.  I took each one exactly as they prescribed, and never missed a dose.  The steriods made me super hungry.  I gained some weight during this treatment, which I guess was good, because I lost it all and then some with the Taxol that followed.  Be sure to drink lots and lots of water.  It helps.

  • mainegirl
    mainegirl Member Posts: 62
    edited July 2013

    I had 4 treatments of AC two weeks apart. Unfortunately, it was the worst part of my whole treatment this past year. Got sick almost every day despite trying five different anti-nausea meds. Lost about 10 pounds-only good part! I also had Neulasta shots after each infusion. My Oncologist said my reaction was extreme so I don't think my experience is the norm. Once I was done it took about two weeks to feel good again and I was getting weekly Taxol & Herceptin by then. Hang in there!

  • encyclias
    encyclias Member Posts: 302
    edited July 2013

    Everybody is different in how they react.  My MO promised me I would not have any nausea, and I didn't.  I was given a pill (Emend) immediately after each infusion with two to take home for the next two mornings.  Worked wonderfully well!  The main SE I got was about the time of the third infusion I began to experience fatigue except in the mornings -- I rushed to run all my errands before passing out in bed after lunch.  Hair loss is a given.  And my white blood cells went down to just a hair below the normal range on both the 3rd and 4th round and I was given precautionary Neulasta shots, with no SEs.  What might have helped was I was set up for three week intervals between rounds to relax and let my body recuperate a bit.

  • sherry67
    sherry67 Member Posts: 556
    edited July 2013

    Everyone response differently ..it took three months for them to find the right combo..I had quit a few SEs none of which were pleasant..sick all the time..Kytril and Decatron finally worked with the scopolamine patch and day of txs Emend/Kytril/Decatron and the scopolamine patch..I was loaded up and still was quizzy..not a good time..Neulasta shots as well which I had severe bone pain I could go on but I won't ..good luck to all who are on tx or beginning tx..

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