Morning musings about origins of ILC

First let me say that I realize that Dr. Mercola is controversial. My feeling about most of his advice is that if it won't hurt me or require me to forego standard treatment, I will consider it. Today's message from him was about Vitamin D. Specifically, I learned that it is possible that a deficiency in Vitamin D may cause the E-Cadherin in cells to decline or be eliminated. As you probably know, for us with lobular, one of the primary diagnoses was a lack of E-Cadherin expression in our tumors. This had led me to wonder if the relationship between Vitamin D deficiency and lobular is even stronger than other breast cancers.



I also came across a blog post this morning that cited this website as a major resource. It talked about the recent increase in lobular among younger women, 40-50's, when it used to be primarily found in those in their mid to late 60's. I didn't find a reason for that, but I did note a possible theory that lobular, while known as slow-growing, might grow faster in younger women. Lobular is usually ER+/PR+, but in a post-menopausal woman, those hormones are not going to be in as abundant supply. Therefore, it might grow faster in younger women, and perhaps there hasn't been time to study this. I'm not saying this to scare anyone, but rather because I know I've looked for an explanation since diagnosis as to how something my doctors said was slow growing could have appeared overnight in my breast. I knew more about my breasts than they did, having just started to treat me at that time, and believe me, it came out of nowhere.



I know these thoughts have not been vetted in the scientific process, but it helps me to understand why I am taking Vitamin D and Femara and motivate me further for compliance. If it helps someone else too, that's great.