HeLa cells.. or an hommage to Henrietta Lacks

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Long ago i read about this woman and her story. I found it fasinating ...

Her cancer cells.. never died. She died in 1951 but her cancer cells are srill alive and used around the world for research..

On the eve of my surgery, i find myself thinking of her.. and who she was, what she felt like...

if you do not know who she is... heres a bit of her story

Henrietta Lacks (August 1, 1920 – October 4, 1951)[1] (sometimes erroneously called Henrietta Lakes, Helen Lane or Helen Larson) was an African-American woman who was the unwitting source of cells (from her cancerous tumor) which were cultured by George Otto Gey to create an immortal cell line for medical research. This is now known as the HeLa cell line.

On January 29, 1951, Henrietta went to Johns Hopkins Hospital because she felt a knot inside her. It all started when she asked her cousins to feel her belly, asking if they felt the lump that she did. Her cousins assumed correctly that she was pregnant. But, after giving birth to her fifth child, Joseph, Henrietta started bleeding abnormally and profusely. Her local doctor tested her for syphilis, which came back negative, and referred her to Johns Hopkins.
Johns Hopkins was their only choice for a hospital, since it was the only one in proximity to them that treated black patients. Howard Jones, her new doctor, examined Henrietta and the lump in her cervix. It was like nothing he had ever seen before. He cut off a small part of the tumor and sent it to the pathology lab. Soon after, Jones discovered she had a malignant epidermoid carcinoma of the cervix Stage 1 (cervical cancer).
Lacks was treated with radium tube inserts, which were sewn in place. After several days in place, the tubes were removed and she was released from Johns Hopkins with instructions to return for X-ray treatments as a follow-up. During her radiation treatments for the tumor, two samples of Henrietta's cervix were removed— a healthy part and a cancerous part— without her permission.[10] The cells from her cervix were given to Dr. George Otto Gey. These cells would eventually become the HeLa immortal cell line, a commonly used cell line in biomedical research.[1]
In significant pain and without improvement, Lacks returned to Hopkins on August 8th for a treatment session, but asked to be admitted. She remained at the hospital until the day of her death.[1] Though she received treatment and blood transfusions, she died of uremic poisoning on October 4, 1951 at the age of thirty-one.[11] A subsequent partial autopsy showed that the cancer had metastasized throughout her entire body.[1]
Henrietta Lacks was buried without a tombstone in a family cemetery in Lackstown, a part of Clover in Halifax County, Virginia. Her exact burial location is not known, although the family believes it is within feet of her mother's gravesite.[1] Lackstown is the name of the land that has been held by the (black) Lacks family since they received it from the (white) Lacks family, who had owned the ancestors of the black Lackses when slavery was legal. Many members of the black Lacks family were also descended from the white Lacks family. A row of boxwoods separates the graves of whites from those of the blacks buried in the family cemetery.[1] For decades, Henrietta Lacks' mother had the only tombstone of the five graves in the family cemetery in Lackstown, and Henrietta's own grave was unmarked. [11][12] In 2010, however, Dr. Roland Pattillo of the Morehouse School of Medicine donated a headstone for Lacks after reading The Immortal Life of Henrietta Lacks.  The headstone, which is shaped like a book, reads:

Henrietta Lacks, August 01, 1920-October 04, 1951.
In loving memory of a phenomenal woman, wife and mother who touched the lives of many.
Here lies Henrietta Lacks (HeLa). Her immortal cells will continue to help mankind forever.
Eternal Love and Admiration, From Your Family

The cells from Henrietta's tumor were given to researcher George Gey, who "discovered that [Henrietta's] cells did something they'd never seen before: They could be kept alive and grow."[15] Before this, cells cultured from other cells would only survive for a few days. Scientists spent more time trying to keep the cells alive than performing actual research on the cells but some cells from Lacks's tumor sample behaved differently than others. George Gey was able to isolate one specific cell, multiply it, and start a cell line. Gey named the sample HeLa, after the initial letters of Henrietta Lacks' name. As the first human cells grown in a lab that were "immortal" (they do not die after a few cell divisions), they could be used for conducting many experiments. This represented an enormous boon to medical and biological research.

As reporter Michael Rogers stated, the growth of HeLa by a researcher at the hospital helped answer the demands of the 10,000 who marched for a cure to polio shortly before Lacks' death. By 1954, the HeLa strain of cells was being used by Jonas Salk to develop a vaccine for polio.[1][11] To test Salk's new vaccine, the cells were quickly put into mass production in the first-ever cell production factory.[16]
Demand for the HeLa cells quickly grew. Since they were put into mass production, Henrietta's cells have been mailed to scientists around the globe for "research into cancer, AIDS, the effects of radiation and toxic substances, gene mapping, and countless other scientific pursuits".[11] HeLa cells have been used to test human sensitivity to tape, glue, cosmetics, and many other products.[1] Scientists have grown some 20 tons of her cells,[1][17] and there are almost 11,000 patents involving HeLa cells.[1]
In the early 1970s, the family of Henrietta Lacks started getting calls from researchers who wanted blood samples from them to learn the family's genetics (eye colors, hair colors, and genetic connections). The family questioned this, which led to them learning about the removal of Henrietta's cells.

Comments

  • LuvRVing
    LuvRVing Member Posts: 4,516
    edited April 2013

    I read the book last year - fascinating story!

  • Grammy98
    Grammy98 Member Posts: 16
    edited May 2013

    I had never heard of her or the HELA cells until about 6 months ago I read the book, "The Immortal Life of Henrietta Lacks."  Absolutely riveting on many, many levels - her health, her culture, how poor "negros" were welcomed to be treated at Johns Hopkins and yet the whole separate but equal doctrine played out even to having separate operating rooms!  I was a child during that time, but was on the west coast and did not see any of that.  Most fascinating, of course, was how her cells have been used for so much research.  We are all indebted to her.

    I hope your surgery went well and you are having a speedy recovery.

  • CelineFlower
    CelineFlower Member Posts: 875
    edited May 2013

    thank yoiu grammy, 

    it went well... but im a baby when it comes to cuts and blood...

    made myself so worked up on friday when hubby took off bandages... i threw up :(

    i feel mutilated... but glad the tumor is out

    It astounds me, how her family never got any compensation.... youd think maybe free medical care?

  • corky60
    corky60 Member Posts: 726
    edited November 2013


    Thank you for reviewing this book. I read it a few years ago. It is well worth the read. I don't recall that there was any consent form that Mrs. Lacks had to sign. Now we sign consent forms and I understand that my cells may be growing in a test tube somewhere. Or worse.

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