Abraxane
I will be starting Abraxane on the 22nd after a port placement and a biopsy to see if maybe I am HER2+ again.
The drug sounds awful and I'm wondering what to expect. How active will i be able to be? My doctor expects me having to skip treatments due to probable low counts.
Comments
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Hello ForestDweller: After Taxol and Gemzar did not work for me, I was placed on Abraxane (3 weeks on and one week off). I just had my 7th one yesterday. I have not had any trouble with counts being too low. Very mild nausea. Onc mentioned that he read very good reports in one of the cancer journals he reads about Abraxane. I hope it is good to you and gets you stable. As with most chemotherapy, I do have fatigue. Again, best wishes on your new treatment plan. Jean
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I am also on Abraxane, 3 weeks on 1 off. Very easy chemo on that schedule. On the other hand tried doing it every three weeks and it was terrible. Lots of bone pain, felt like I had the worst flu ever. I have been on it since aug. Its working very well so far. Tumor markers are way down are staying stable so far. Other than the hair loss and being really tired, its been the easiest chemo Ive done. Hope you have good results.
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I'd have to agree with Marywh. I'm on my 6th month of Abraxane treatments. I think the fatigue is the hardest. My counts have been good. I'm surprised but pleased.
All the best. -
I'm pretty sure he told me it would be every three weeks. Why would he choose this schedule if the weekly one is easier?
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i was on abraxane for 8 months 3 weeks on 1 week off and i had very little nausea and the only thing was tired like everyone else said hope it works for you ...hugs chris
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I started on the 3 weeks on one week off schedule. I did have problem with my white blood cell counts and was switched to 1 week on one week off schedule. I still occasionally have to postpone a treatment due to neutropenia, but have had regression with Abraxane none the less. I feel good and have good QOL on Abraxane. Love it.
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Could have something to do with the type of insurance you have. I know I had to get approval before they would do a weekly schedule.
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Maybe so. The insurance has always been hassle-free, for which I'm very thankful.
I dread shopping for a wig. I didn't bother with one during my initial treatment 4years ago. -
My hair is coming back slowly. I hate wigs, and am getting so tired of hats. This is my third time around, but you never get used to it. Was in Fl. last week where anything goes so went bald all week. It was so nice.
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I also tolerated Abraxane well. 6 months/3weeks on, 1 week off. Very few side effects. Wishing you the best!!
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Forest, I am with most of the others. I did 3 rounds of 3 weeks on and 1 week off. I got the chemo on Wednesday and I was very, very tired on Fridays. When I got off work I would go home and sleep. I also had some nausea from time to time. The absolute worst for me was losing my hair again. It went fast too. In the first couple of weeks after treatment.
Good luck and let us know how you do.
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Forrest, it is not fun hearing that you have to do chemo again and perhaps when you heard the three weeks in just being upset he meant 3 weeks on and one week off.
I did Abraxane with 3 weeks on and one week off for 6 months and I think I missed one treatment. That was late in the treatment and it was due to the neuropathy in my hands and feet. This was the first IV chemo that I have done since being diagnosed as Stage IV. I found it to be quiet easy. Much easier for me that AC that required steroids with the initial diagnosis. Steroids absolutely tear my stomach up and Abraxane does not require steroids.
I hope it is an easy chemo for you also. Best of luck.
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Naniam my next question was going to be if everyone gets premeds. My oncologist said I would get steroids and zofran.
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Hi Forest.
I've been on Abraxane for 4 weeks & have just come out of hospital after having fibrous pneumonia as a (rare) SE. It's been a really easy treatment for me, only had a couple of mouth ulcers for a day or two at the beginning. Apparently the fluid will take up to 3 weeks to clear but I feel fine & am carrying on singing with the choir. Having a check-up lung scan on Friday to see if I can carry on with A.
Good luck with it.
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My onc doesn't do steroids as a pre-med, but that might be because the weekly dose is smaller. I do get Zofran as a pre-med before the drip. Jean
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I am on Abraxane. I've had 4 total infusions 3 weeks on 1 week off. The worst side effect I have is that food and water taste awful. I can taste sweet but can't taste salt. I get my infusions on Wednesday's and get fatigued on Saturday. I also get a little diarrhea about twice a week. I get less steroids before the infusions then I did while on Taxol. I kept all of my hair on Taxol, but it is now thinning out with the Abraxane. Overall I think I am tolerating the Abraxane pretty well. My onc says I'll be on it for a while.
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Macyhen....I have been to your lovely city several times. Im being treated in Fort Smith.
I was hoping there wouldn't be any taste changes. Sweets always taste good no matter what treatment I'm on. -
Forest - I had a good long ride with Abraxane. I was on the 3 weeks on and 1 week off regimen for 15 months and it kept me stable. All in all - a pretty easy chemo. The bad - I lost my hair though it did start to regrow although very very slowly around month 6. My nails lifted, but I didn't lose any. Other wise women advised I keep them polished with Sally Hanson Hard as Nails and keep them cut short so they don't catch on anything. Good advice. Worked forme. I still have one nail that looks wonky, but all other nails returned to normal even on Abraxane. I had some neuropathy in hands and feet, but just got a more comfy and wider shoe. No big deal there. I had no problem driving the hour round trip myself. I did look forward to going home and would then get in a couple hour nap. Then woke feeling OK. I was a bit draggy on the Abraxane, but again - not unbearable at all. Wish that love affair with the stable boy could have continued longer. {sigh} Needed no pre-meds with it. Hope it will work for you, and maybe you'll be able to sweep right past that fickle stable boy and meet Reggie or Ned! Give them my regards!
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15 months is a long time compared to the 5 months average I read about. Good for you! Whenever another treatment fails I feel so near death.
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ForestDweller my hubby and I recently moved here from Los Angeles. I absolutely love it here. It is so peaceful. So different from the hustle and bustle of L.A. I was diagnosed out here and the treatment I am receiving is excellent. The Doctors and nurses are compassionate and caring. I hate having this illness, but since I do I'm happy that God lead us here.
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Does anyone else on Abraxane have bowel issues. I have diarreha quite frequently with awful stomach cramps. My mo wants me to get the scope in my tummy thingy ( i don't know what it is called). I had my 5th treatment today.
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I often had diarhea the day of chemo after the abraxane infusion. I would usually take an Immodium tablet right before chemo and that seemed to take care of it.
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I take Imodium everyday but it hasn't helped. Sometimes it gets so bad that I vomit at the same time. I think it might have a lot to do with what I am eating. Everything taste awful except veggies and fruit. Mo told me no fresh fruits or veggies because of the potential for bacteria. So I eat cooked veggies and canned fruit. I'm going to cut out the butter on veggies and maybe this will help. I also can tolerate the taste of hot spicy foods but evidently they are not agreeing with my tummy, so no more for me. I hope this works cuz I'm tired of visiting the throne.
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Isnt it weird how chemo works on different people. The abraxane constipates me so bad that even with alaxative I still have trouble going.
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Yes marywh, it is funny because when I first started Taxol the constipation was horrific. But after that resolved itself the diarrhea kicked in.
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Until someone mentioned that everything tastes terrible, I had forgotten about that. Guess I'm used to it. Been doing chemo since April 2012 (Taxol, Gemzar and now Abraxane), but they are right on......food and water don't taste the greatest. I can't taste salt either, but seem to want chocolate cake or cookies a lot! Haven't had much hair in a year, so forgot about that part too. Jean
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I've taken a probiotic daily for several years, along with my other vitamins/supplements. It's supposed to be good for maintaining appropriate (good) bacteria levels in the colon- promotes good colon health supposedly. Wonder if this helped with this?
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I also take a probiotic daily, but it hasn't helped with my bowel issues. I'm so tired of my stomach hurting, but if this is the worst se I'll have while on Abraxane I will have to learn to deal with it. I will have to keep the ph and vaseline close by.
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I tolerated Abraxane pretty well, but it did make me very tired. Never had problems with nausea, though I got Aloxi as a pre-med. The most annoying thing was the stuffy/runny nose. I got nosebleeds too, though that might have been more from Avastin, which I had at the same time as Abraxane.
Good luck!
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I get nosebleeds all the time, I'm 3/1. Bad cramps now just under ribs, onco said that was Abraxine. Had violent D initially for 6 weeks now its day after infusion.
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