Aphinity Trial Pertuzumab

I am still around.  Had treatment #5 wednesday- it hit me pretty hard.  I was starting to get excited about only 1 more chemo- but really- I still have to show up 3 weeks later and get the h/p infusion...and 3 weeks after that and 3 weeks after that....Maybe I won't feel so bad but I am still owned my my oncologist.  Really getting tired of having cancer.

Well two rounds of chemo and both times ended in hospital with diverticulitis- and on IV antibiotics... go figure... Happened just as white count went down on day 6-7. Hopefully they will figure this one out since I have 4 more chemo rounds to go and am getting tired of not having a bit of a normal life.... Hair is about gone, but I was surprised how nice and round my head is! ;^}

I am taking the meds and haven't been nauseated, just bloating and abdominal tenderness.

Hi Shanny - so good to meet you - not much activity on this board but I am done with chemo and onto the Herceptin/ "P" drug every 3 weeks - and I will tell you that it is all managable - just keep on the nausea meds after your chemo and then just go with it. I am shocked at how fast the time has gone. I am now doing radiation - just had my 7th of 30 and that too is really OK - just weird to have to be some place every day. If there's anything you want to know please ask- take care - Marilyn

Thirteen years.  WOw.  I need to reread all my study info!

I am sitting in the treatment chair now, waiting for the pharmacy to randomize me. It will be my 12th treatment. I too get jealous when people come and go and I am still sitting but I am glad of the special attention I get and that I will be followed for years. I now call my treatment day, my movie day and I bring my iPad loaded with movies!

Damiana & Jeb -   I know what you mean.... it seems like it takes FOREVER!!!! I get jealous too. What really bugs me is sitting next to someone who is really negative and chatty.... ugh.  I get that they need to vent - but I want to stay in my "happy bubble".  I figure I'll get my last infusion of Herceptin and the "P" drug in July. I also am now considering myself cured.  I decided to think that way... and so I hope that my mind set will help the outcome. Anyway - good to hear from you both - this site has been pretty unactive

I've had some heartburn over the months - Tums help - but if it gets really annoying I'd let my study nurse know.

Do you guys get achy? I do - especially my things... I feel like I'm 100 sometimes.

Marilyn

I've gotten heartburn, mild heartburn, but I don't think I've had that from just the H/P. 

On another note, do any of you get from time to time extremely weird smelling pee?  It will either smell like I've eaten asparagus, when I haven't, or it will have kind of a burnt/tarry odor.  It's just from time to time, not continously.  Weird though.

Cvmarilyn, I'm deciding the same thing.  There is good evidence to support that this is true, and I think it is better for my health to go with that.  I also finish the H/P in July.

Marilyn, but ain't it great to be DONE!?  I went to a party tonight and an acquaintance asked me what I've been up to lately.  Just an acquaintance, so he hasn't a clue about the whole having cancer thing.  I just thought to myself -- what am I up to?  I'm up to NOT having to deal with  cancer treatment!  And I don't have a single doctor's appointment next week.  Not one.  I'm SO excited!

Ok so the pee thing -- when does it happen?  It's kind of random for me, not like the day after an infusion or something, necessarily.  It's really weird. 

Hi Marilyn,

That's not a thread I've been following, but I'll look.  I guess if some TCH people have it, then it's not the P.  But also it's reassuring b/c then it's just a SE rather than anything to worry about.  I'm guessing it must be the H since i'm done with the TC.

I think I look a lot older -- usually people think I'm younger than my age; I'm not getting that lately.  I think in 6 months I'll look a lot younger than I do now.  But yes the cold caps worked!

Yep - my nails have been tearing too - and sometimes I get this gap underneath the nail so the white goes down into the pink - it's weird - my toe nails have been fine - just the fingernails.

How about neuropathy? I have it in my feet - especially the side/edge of my left foot - but only when I don't have shoes on and on our hardwood floors

I think my skin looks good - but I probably look older becasue my hairs come back in kind of white on top and then red on the sides and back.  I kind of liek it short - it's rather "edgy" - and Lord knows I feel pretty strong after the assault on my poor boob

I sure can't drink anymore - I had a glass of wine the other night and it brought on a major hot flash and my family told me I was RED!!!

How's the weather today?  can you just stay inside and hunker down by the fire?

Marilyn

I don't really have heartburn but I do burp a lot, sometimes without much warning and kinda loud! So graceful! I can manage to drink one beer without a major hot flash as long as I am also drinking water. I find water very helpful in managing those. I am lucky to not have any problems so far with neuropathy.



Damiana9, I noticed that you have just started some radiation in addition to the surgery and chemo you have already endured. Is that because of the lymph node involvement? How is that going? When will you able to have you TE replacement?



Did any of you have any reactions to the chemo drugs? On my 6th ( and last chemo infusion ) I had a reaction to the Carboplatin. I was 42 minutes into the hour infusion when suddenly my feet started itching and burning like there were fire ants on them. I was tring to take off my shoes when it attacked my hands. My friend got the nurse and she yanked the drug, gave me antihistamine and called the doc. Luckily the reaction stayed in my hands and feet and subsided in about 30 minutes. I am now officially allergic to Carboplatin. (And skin adhesive but that's another story!)



Jane

I think it was more scary for my sister and my friend who were with me! It was my 6th and final round and the nurse said that is more likely to happen on the 6th or 7th round. My nose started to run today and it is the end of the first week of my 12th cycle. I can't figure any rhyme or reason. Jane

Just catching up on these recent posts!

I am still getting the TC part, so I can't really comment on much yet, but I get terrible heartburn for about a week after each treatment, have the runny nose, and I did notice the weird smelling pee, but just attributed all of those to the chemo drugs.

As for the allergic reaction, that is scary!!! I was told that after 6 of the carboplatin treatments, if I ever needed it again, I would have to get the benedryl before every infusion because the carboplatin is prone to causing that.  Hopefully, I won't ever have to worry about that.  I am doing treatment 5 of 6 next week.

Thankfully the other side effects I seemed to be having at the beginning ( the rash and diarrhea) seem to have subsided and I am saiiling through this relatively easily now.

Hope everyone else is continuing to do well, and looking forward to being done!

Damiana9 - I am sorry you have to endure RADs as well as chemo. UGH. Every day. I elected to have mx to avoid that. It was a good thing I did because my tumor was not 1.8cms like they though but was actually 3 tumors with different expressions totally 4.6 cms. The largest one was 2.6cms and HER2+.



Shanty - Good luck with your last two treatments! They have been giving me Zyrtec before every treatment but they did give me Benedryl for the reaction. I am glad your SE are waning.



I met with my BS yesterday and he felt me all up and checked out my inverted nipple on the left. He did not feel anything significant but has ordered sonograms and an MRI even though he said he does not think that it is cancer. It is an unsettling development but I will try to not worry about it. I have been feeling quite a bit better lately and even hope to go skiing on Monday with my sister!

Jane