mixed IDC and DSIC and possible LCIS -- (MRI tomorrow)

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LaurynSister
LaurynSister Member Posts: 52

IDC -- Grade II/III, 1 mitotic rate with 1 mitosis/10hpf -- tumor size 1.5 cm - 2.0 cm

focal intermediate grade DCIS (cribiform type is present but not extensive), estrogen/progestrone levels strongly present.

In both breasts -- don't know about lymph nodes yet until MRI tomorrow. Please Pray!

E-Cad + and -, which may suggest a tubulo-lobular differentiation.

not sure about HER+ or - yet either.

Noticed drainage from both breasts. Stopped taking estrogen pills the other day (was dx last Friday), and breasts started hurting, and also my shoulder! What does this mean, i wonder? Lymph nodes? MET to bone?

If you know anything about this patho report or prognosis (good or bad), please tell me. Thanks!

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  • LoriBird
    LoriBird Member Posts: 5
    edited September 2012

    LaurynSister, In 2007 I was diagnosed with a 5 cm tumour -  invasive tubulo-lobular carcinoma, with LCIS & DCIS components.  Quite rare-approx. 2% of all breast cancers!  ER+/PR+, HER2-.  4 lymph nodes were positive.  Right side mastectomy.  The cancer was deemed to be beginning to behave more agressively and my onc. put me on a dose-dense regimen of CEF, followed by 35 radiation treatments.  Kicked the crap out of me, but here I am, 5 years later, still alive and kicking!  Just remember to "do what you gotta do".  As hard as it is, try not to live too many days down the road - take them one at a time.  Good luck - praying for you.  Keep me posted.  :)

  • LaurynSister
    LaurynSister Member Posts: 52
    edited September 2012

    thank you so much, sweet Lori Bird, for your reply to my post. I have been really anxious since the diagnosis last Friday. It was like a punch in the gut. Had an MRI today, now to wait to see what the results are -- if it  has spread any. My shoulder has hurt a little, so I wonder if it is in the nodes there or bone. I also have bad stomach probs already (diverticutis) and need a colon resection, so this is gonna be tough for me. But i will try and follow your advice to live one day at a time; be thankful for each good day....and remember the bad days will pass. I am so glad to hear you are doing well! Very encouraging! Please keep in touch - God bless u! LaurynSister

  • LaurynSister
    LaurynSister Member Posts: 52
    edited September 2012

    well, my dear sister's MRI turned up 2 inch tumor in left breast and a smaller one in the right. Both side nodes are affected, though dont know how many. The doc just said "some" nodes. They are going to do a complete mastectomy and take lymph  nodes. I am going to help her in every way i can to fight and win over this. She is so precious to me. THe only problem is we live an hour away from one another, and I have two sons I have to look after, as well as some animals. But surely they will all be okay while i go help Sis.

  • LaurynSister
    LaurynSister Member Posts: 52
    edited September 2012

    tumor in both breasts and is in some lymph nodes (dont know how many yet). Radical mastectomy coming up, plus treatments. What treatments did you take Lori? Hormonal? radiation and chemo --  how can we get through that without getting really sick? What's t he best things to eat that won't make you sick?

  • LoriBird
    LoriBird Member Posts: 5
    edited September 2012
    Hi LaurynSister!  I'm sorry you're going through this Frown.  As my brother said when I was diagnosed "that just sucks".  I had a right side modified radical mastectomy.  About 6 weeks later, I began 6 cycles of dose-dense chemo.  My onc. explained it to me as "blasting" the cancer quickly, as opposed to slower and more steadily.  The first day of each 28-day cycle began with taking oral cyclophosphomide pills, then going for IV chemo with epirubicin and 5-flurourisil.  The pills continued for 14 days, and I was blasted with IV drugs again on day 8.  So over the course of the 6 cycles, I had 12 IV chemo treatments.  Days 15-28 were drug-free. I didn't really have much nausea/vomitting, due to the Kytril pills taken for a couple of days during and immediately followed IV chemo.   However, I did have to deal with terrible mouth sores and a pretty bad case of mucocitis which had me hospitalized for 2 weeks in my second cycle at which point my dr. adjusted the dosage of the IV drugs.  The 3rd cycle was kinda bad, but after that (except for the mouth sores that always appeared around day 15 of each cycle), I wasn't that sick.  I was really, really tired and did require a couple of blood transfusions, which helped tremendously!Laughing  About a month after chemo was done, I began radiation - 35 treatments.  I've been on Arimidex, which is an aromatase inhibitor thought to help the body block production of estrogen that fuels hormone receptor + b.c. for 4 1/2 years.  It's recommended for 5 years post-treatment, so I'm nearly done!  yay!Tongue out Aromatase inhibitors are only given to post-menopausal women; otherwise, I believe it's tamoxifen for a few years. As for what to eat? Whatever you WANT!! I found cucumbers and canteloupe helped when my mouth hurt. Basically, if you can tolerate it, you can eat it!!! Also, drink fruit nector, as opposed to fruit juice - I found a great kiwi nector at WalMart! I wish you a trouble-free treatment period - I met a few women who were not sick at all, so remember that! Please keep me posted on your progress and if there's anything I can tell you, or questions I can answer that will help you, please let me know. Hugs!!Wink
  • LaurynSister
    LaurynSister Member Posts: 52
    edited September 2012

    Thank you sooo much Lori Bird, for some encouragement and tips on how to make it thru treatments! Love you!! :)

  • LoriBird
    LoriBird Member Posts: 5
    edited September 2012
    Love you too, LaurynSister!!!  Please keep me posted on your progress.  I forgot to tell you to look for humour - in books, movies, tv shows, life... wherever you can find it, it will help.  Get your hands on a book called "Life's Too F***ing Short" by Janet Street-Porter.  She's British and this book is hilarious!!!  In fact, I think I'm due to re-read it - it's that fantastic.  I was practically falling off my chair laughing out loud.  My husband thought I had really lost it! Tongue out  Talk soon!  xo
  • LaurynSister
    LaurynSister Member Posts: 52
    edited September 2012

    Hi Lori! I will def. have to get that book :) Laughing is indeed good medicine -- it is so good for the body and soul :) Thank you for your encouragement! Love you! Keep in touch!

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