Wonderful News - Evista better than Tamoxifen

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Catherine
Catherine Member Posts: 305
edited June 2014 in Recommend Your Resources
Wonderful news! Good Morning America featured a segment that a study of 20,000 post-menopausal women discovered that an arthritis drug - Evista (Raxolfine) had proven even more effective than Tamoxifen as a prevention for breast cancer. It has also been shown to have fewer side effects. It needs to be approved by the FDA but they expect it to be approved within the next few months.

Catherine

Comments

  • daylo
    daylo Member Posts: 1
    edited April 2006
    Hi Catherine...Is this only for estrogen + breast cancer?
    I think it is...anyone know for sure?
  • olecrowe
    olecrowe Member Posts: 1
    edited May 2006

    Isn't Evista also for osteoporsis? I also saw a report about it being at least as effect as tamoxifen.

  • Hattie
    Hattie Member Posts: 414
    edited May 2006
    It's not actually prevention but rather risk reduction, and it is approved for high risk women, not those dx with bc. check the recent news or research news on the home page here for more info.
    take care,
    --Hattie
  • mags
    mags Member Posts: 233
    edited May 2006
    Hi ladies, and I think you have to be post-menopausal to take it unlike tamoxifen where you can be either.
    Mags
  • purple32
    purple32 Member Posts: 3,188
    edited July 2012
    Evista is not  a tx ...once you have BC , Evista does not work for you.  A good prevention.
  • OneBadBoob
    OneBadBoob Member Posts: 1,386
    edited July 2012

    I believe studies are proving that Evista gives the same protection against recurrance as Tamox, but it has not yet been approved by the FDA for that purpose. They work in basically the same way.



    Many oncs are prescribing Evista off-label for post-menopausal hormone+ BC survivors, who simply cannot tolerate the AI's or Tamox.



    Let's all keep an eye on this in the coming months.



    I also believe there was a time when AI's and Zometa were only given to stage IV patients. Now both are used in early stage breast cancer patients.



    I don't have any research on this at my fingertips. So please feel free to offer opposing opinions.



    I started with Tamox and gave that up because I was a poor metabolizer. I then went on Arimidex for three years and got to the point that it was effecting my memory and mental functions beyond what I could tolerate.



    I also took Zometa 7 treatments at six month intervals for bone strength and because at that time it was thought Zometa would be helpful in preventing recurrance or mets in early stage BC patients. I finished all of those.



    I spoke with my onc and consulted with two additional research oncologists (one from NYU and one from Yale) when I was considering switching from Arimidex to Evista and after reviewing my case both consulting oncs and my onc agreed Evista would be a good choice for me.



    So, this week I am celebrating five years from my diagnosis and feel this was the right choice for me.



    I had a mastectomy with reconstruction, chemo and no radiation

  • OneBadBoob
    OneBadBoob Member Posts: 1,386
    edited July 2012

    I believe studies are proving that Evista gives the same protection against recurrance as Tamox, but it has not yet been approved by the FDA for that purpose. They work in basically the same way.



    Many oncs are prescribing Evista off-label for post-menopausal hormone+ BC survivors, who simply cannot tolerate the AI's or Tamox.



    Let's all keep an eye on this in the coming months.



    I also believe there was a time when AI's and Zometa were only given to stage IV patients. Now both are used in early stage breast cancer patients.



    I don't have any research on this at my fingertips. So please feel free to offer opposing opinions.



    I started with Tamox and gave that up because I was a poor metabolizer. I then went on Arimidex for three years and got to the point that it was effecting my memory and mental functions beyond what I could tolerate.



    I also took Zometa 7 treatments at six month intervals for bone strength and because at that time it was thought Zometa would be helpful in preventing recurrance or mets in early stage BC patients. I finished all of those.



    I spoke with my onc and consulted with two additional research oncologists (one from NYU and one from Yale) when I was considering switching from Arimidex to Evista and after reviewing my case both consulting oncs and my onc agreed Evista would be a good choice for me.



    So, this week I am celebrating five years from my diagnosis and feel this was the right choice for me.



    I had a mastectomy with reconstruction, chemo and no radiation

    Sorry for the double post. I deleted the first one.
  • purple32
    purple32 Member Posts: 3,188
    edited July 2012

    YES Catherine, you are right-----for prevention , as you said.

    I asked all 3 of my expert drs at MassGeneral and none would give me Evista ..the horse is out of the barn.

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