taxotere side effects

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  • kltb04
    kltb04 Member Posts: 1,051
    edited June 2012

    Oh wow hikergal you have quite a lot on your plate. My personal experience when I had nuelasta was I felt bad the week of treatment so I didn't do anything or go anywhere. Week 2 (one week post tx) my labs would show my WBC was low still so I would try to stay in that week. By week 3 (2 weeks post tx) my WBC would be back to normal. We went on vacation during my "good week" last month. Movies, restaurants, shopping. We drove though and didn't fly. I would ask your MO on that.



    If I did need to run to the store or whatever during a low WBC week I just took precautions. Didn't use a cart or wiped it down first. Germ x when I got back to the car etc.

    Edited to add: I am a germ phobe when perfectly healthy so those are things I do anyway!!
  • kltb04
    kltb04 Member Posts: 1,051
    edited June 2012

    Oh btw my temp went up to 100 last night so I went ahead and called MO. She had me start on oral antibiotics just in case. I have a bit of a stuffy nose so I don't know that antiobiotics will do any good but I know it's protocol.

  • Alicethecat
    Alicethecat Member Posts: 535
    edited June 2012

    Hi Kltb

    Good luck with the antibiotics.

    I think they are worth it!

    Alice

  • Tazzy
    Tazzy Member Posts: 2,546
    edited June 2012

    Hi Hikergal,

    Its so hard when our counts are low and we know we are susceptible but dont want to put ourselves in a bubble.  for the first week I normally felt so crap I didn't go out anyway.   Then if I went grocery shopping I tried to go during the week and early.  If you go with someone let them line up to pay so you can go to a more non crowded area.  If not, i just tried not to get too near people - touch wood I haven't to date had any colds or infections.  good luck.

    I do know someone who flew and her MO told her to wear a mask at the airport and in any crowded places... I agree with kltb - check with you MO.

    kltb... hope the antibiotics kick in and you feel better soon.

  • Hikergal
    Hikergal Member Posts: 74
    edited June 2012

    Thanks for the advice on traveling, etc.  I asked my MO at the time of BMX if I could travel during chemo and he thought it was ok.  I asked the oncology nurse last week about wearing a mask and she did not think it would help but I think it is worth a try!  Glad they gave me Neulasta yesterday, maybe that will help me from crashing too badly.  Another oncology nurse said the distraction of the trip would be good, so I guess I will wait and see how I feel next week.

    ktlb04 hope you feel better on the antibiotics!

  • ljhm
    ljhm Member Posts: 60
    edited June 2012

    Your nurse said the mask wouldn't work probably because as soon as you get any moisture (your breath) on them they are pretty useless.  I go out all the time but do not let people hug me and wash my hands constantly.  So far so good.  Finally feel normal on the 10th day after treatment.  Hopefully, I can forget how crappy I felt before the next treatment on July 4th.  Have a good weekend everyone.

  • marjie
    marjie Member Posts: 1,134
    edited June 2012

    I had aches and pains all through taxotere, but was also getting 10 days of Neupogen shots after each chemo.  I had Neulasta, but for some it doesn't work so that's why I had to do the Neupogen shots.  Tylenol and warm baths were very helpful.  I lost all my eyelashes so taxotears were brutal - I could barely see.  My hands and feet were iced during tx to protect my nails - I finished Taxotere on Feb 2 last year.....and lost my big toenail in the summer, other than that, my nails yellowed but are now back to normal except that they are super soft.

    My chemo regime was FEC-D(Docetaxol or Taxotere) - I had 3 FEC treatments then 3 Taxotere (also started Herceptin).  I was hositalized all through FEC and told I was "critically ill" but really didn't feel all that bad.  On the Taxotere, I felt worse, but medically I was in much better shape and did not end up in the hospital...go figure.

    Never had any mouth issues but I rinsed lots with Club Soda.

    It's doable - not pleasant, but keep a sense of humour and a positive attitude.

  • Tazzy
    Tazzy Member Posts: 2,546
    edited June 2012

    marjie... ditto on the taxotears... brutal eh?   So I want to share my wonderful news that today I had my last treatment of taxotere (#4) and last infusion of chemo - doing the happy dance until the pains set in Laughing  So far so good with the nails... yes very tender but hoping to hang onto them.

    Now I await the surgery date and then rads.

    To all of you just starting, hang in there, its doable, chemo sucks but it works.

    Hikergal... enjoy your trip.

    Have wonderful weekends and hope any SE's are minimal and bearable.

  • liefie
    liefie Member Posts: 2,440
    edited June 2012

    So glad for you, Tazzy! Yeah!!! I celebrated that day on May 7, and believe it or not, I hardly had any side-effects after Taxotere #4. The worst one was #3 - tight chest, difficulty breathing, racing heart, very weak. The three weeks after #4 was a breeze, really. I wish the same for you. Only complaint is the Taxotears that kept streaming until about two weeks ago, but it is completely gone now. No Kleenex in sight!

  • ljhm
    ljhm Member Posts: 60
    edited June 2012

    Congrats Tazzy.  I had my first treatment 11 days ago and no hair loss yet.  When did you lose your hair?  My nails are fine so far and most SE's are gone.

  • Tazzy
    Tazzy Member Posts: 2,546
    edited June 2012

    Oh! liefie... I have the SE's are kind to me this one round.  Hope that the mentality of it being the last will work.... positive energies etc.   Took that long for the taxotears to stop eh?   Did your stop immediately after your treatment.  Mine do... for about 8-10 days... when I was looking through my chemo journal seems that I get the pains after the neupogen shots.... the tears stop when the pain starts...then the pain stops and the tears start???

    ljhm - hair loss.  When I was dx'd my hair was just past shoulder length - soon as I knew it would go, I went and go it cut short... really short.   I couldn't stand the thought of it coming out in clumps all over the place.  Then when it started to thin... was about 2 weeks after first treatment I made an appointment at the cancer agency where they shave your head - and went and got it shaved off.   For me anyway it was a lot less traumatic to go that route.   I never went with wigs either, just hats, scarves, caps and turbans.   I have grown very fond of them and invested in lots of colourful scarves to match different outfits.   Do you have a Look Good Feel Better workshop/room near you ?   They provide a wonderful service - everything is free and/or by donation.  Not sure where you are in the world.

  • liefie
    liefie Member Posts: 2,440
    edited June 2012

    Tazzy, it really seems everybody is different. My tears used to run during the last week and a half of every round. After my last chemo on May 7, it also started in the second week after and kept on till around June 10, after which it faded away gradually in a few days' time. I would constantly be wiping tears away while it was going on, and the skin around my eyes became red and puffy, as if I wasn't run down enough. it will be over soon for you too, and your outlook on life will become much less blurry - LOL.

    The only thing that I am dealing with now is a sore, red spot on my chest above the breast. This is after 17 radiations, with 8 more to come. I am going to look like a cooked lobster at my daughter's wedding in 12 days . . . oh well, we don't have too many choices in this business, do we? The radiations continue till the day before the wedding on Thursday, July 5, and I will finish radiation the day after. It really sucks. At least I have bounced back from my chemo, and I feel so good with my energy levels way up. So grateful for that, because just three weeks ago I was still so weak. Wishing you a good, SE free weekend, Tazzy! The worst is over.

  • Tazzy
    Tazzy Member Posts: 2,546
    edited June 2012

    I have to say that the taxoteres is the most annoying, irritating of the SE's - for me anyway.   For the red and soreness under the eyes, I have been using vaseline, so far its working.

    Rads I dont have to think about yet... after surgery.  And we dont have much choice in this business.   We have to put on our big girl panties... pull 'em up and suck it up. 

    Starting to feel a little fuzzy around the edges so am going to settle on the sofa with my book, watch the rain fall (who can believe first weekend of Summer) and just rest up.

    Ladies, hope all your SE's are minimal.... lets all remember they pass.

  • Hikergal
    Hikergal Member Posts: 74
    edited June 2012

    Congrats Tazzy on your last tx!!  Smile You give those of us just starting  hope that we can get thru it too.  Seems like a new SE each day, I am day 4 and the nausea is gone (yah) but running a low grade fever.  Had the Neulasta day after chemo and was pretty achy even on Allegra.  Taxotears should be interesting for me--I have a dry eye condition and have my tear ducts blocked.  I guess I will be a fountain of tears for awhile!

    Anyone know of some funny movies?  My oncology nurses recommend laughter during chemo so I am hoping to watch some  funny movies when I am resting.

    liefie, wish you luck at the wedding.  Try not to do too much which I am sure is going to be hard at your daughter's wedding.  

  • Tazzy
    Tazzy Member Posts: 2,546
    edited June 2012

    hikergal - from a dry eye condition to possibly the opposite.   Depends on what your humour is I guess... Bridesmaids I thought was hilarious.  I love any Monty Python movies (but I am originally from the UK, so realise that our humour is sometimes a little different to people from the States).  I am also known to have a bit of a warped sense of humour.   Really glad the nausea has passed.  I am so very grateful through all my tx's I did not get nauseaus.

    Keep smiling ladies - even through the SE's and anything else.  

  • ljhm
    ljhm Member Posts: 60
    edited June 2012

    Well my hair is starting to fall out in tufts. Guess I'll thinking about shaving it.  My hair is really long so it's going to be a shock. 

    Thrush:  I had a really brad thrush infection due to the steroids, nystatin was helping but not curing it.  What I found worked and really fast was gargling with 1/2 vinegar and 1/2 water, it is an old cure but definitely works.  Will be tough to use when the mouth ulcers come back but for the first 3 steroid days I should be able to manage it. 

    Today I feel the best I have felt, 13 days after my first treatment.  Next treatment Monday and at this rate I should be bald by then.  Pissed off that my onc didn't mention cold caps before my treatment, oh well, big surprise.

    Tazzy:  went through the look good program it's great isn't it.  I'm in Ontario.

  • Tazzy
    Tazzy Member Posts: 2,546
    edited June 2012

    ljhm... I said that the look good program was like make-up for the soul.  And if you can, I found it way better to get rid of the hair first... that way we are still in control.  Least that's how I felt.

    Cold caps weren't mentioned to me...but all 3 of my chemo's make you lose your hair - guess they thought what's the point.  I dunno.. its gone now and as I'm finished I hope that in a few months it will be well on its way back.

    kltb - how are you ?  did the anti's work?

  • ssj
    ssj Member Posts: 1
    edited June 2012

    Hi --- God Bless You!   I'm new to this Taxatore also (this time, after 11 years) Second treatment on 6/19. First time was ok - Now a TERRIBLE ITCHY rash. Read old posts that said it is a side effect that DOESN'T go away???  Can this BE???  Other than that, I am feeling pretty good on day 6.  Can anyone clue me in?   sj

  • kltb04
    kltb04 Member Posts: 1,051
    edited June 2012

    ssj - I would call your onc - they will probably tell you to take an antihistamine.  Some of my friends on the March chemo board have had the issue on Taxol.

    Tazzy - thanks for asking, yes, I suppose they are working - the fever never went any higher and if I still have any lingering/low grade, I haven't noticed it enough to check.  Yeah, I was kind of a "what's the point" gal on the cold caps too - I just don't have the patience to do the extra work.

    ljhm - I went ahead and cut mine down with DH's razor to about a #3 when mine started coming out and then he buzzed it on down to a #1 for me.  The stubble drove me mad so I went ahead and razor shaved it (which probably isn't a great idea just because of teh risk of cutting yourself).  Mine has steadily regrown in little patches even through chemo.  Just stubble mainly and not all over.

    I have been down and depressed the last few days but feel myself coming out of it today.  Even got on the treadmill for a few minutes...not fast and not long - just 2 sessions of 15 min each - but it was something.

  • Melrosemelrose
    Melrosemelrose Member Posts: 3,018
    edited June 2012

    ssj- If you have a very itchy rash, you  want to call your onco today and let your onco know.  That itchy rash is a side effect and your onco may be able to prescribe something to help you.  You need not suffer through chemo side effects.  Don't hesitate to call your onco because it's his/her job to help you post chemo treatment and oncos want their patients to call.  Not a time to try to self medicate.

    lijhm- I had waist length hair in mid February 2012 when I had my partial masectomy.  Then I had it cut at Supercuts to a short bob before my mid-March for my UMX.  After I started chemo and the weekend before round #2, I made five little ponytails on the front and upper sides and snipped those little pony tails off.   I got tired and annoyed of hair everywhere and using a lint roller to clean myself, my clothes and pillowcase off all the time.  Yes, I have them in case I decide to get industrious and crafty to make a hair halo.  My DH used some electric clippers w/ a 1 inch cutting guard to give me a very short short pixie/boy cut.  He left the front alone since I told him i wanted to leave it the length I had set and cut the ponytail at.  It was a very exhilarating and liberating feeling when I took action and cut those pony tails off.  I have not shaved/buzzed my head since then and don't plan to cut anymore off.  I still have what I call a thin veil of hair all over with my original hair and some very thin new hair and some hair is trying very hard to come back.  I still have two more rounds of chemo after round #4.  I did not do the close shave because I knew I couldn't handle the drastic and very abrupt change to smooth baldness after having long hair for many years and it is my personal science experiment to see if all of my hair would fall out and when. ( I'm kind of a walking science experiment anyway with being on that Herceptin B-47 clinical trial and using myself as the personal test subject to see if regular 24 hour Claritin prevents bone pain from my Neulasta shot.)  As for the hair, take control over the hair before it controls you.  You do what you are comfortable with on your terms and your time.  HUGS!!!!

  • Melrosemelrose
    Melrosemelrose Member Posts: 3,018
    edited June 2012
    ktb04- Be kind to yourself  which translates to be easy on yourself.  You have been in chemoland longer than I have and it is certainly to be expected to feel a little down at times.  Being tired and fatigued doesn't help either.  Glad you came here to vent!!!  After my #2 round of chemo, it seemed like I was crying a little almost everyday of basically nothing.  I know it was partly due to the chemo since that is about the time I started into chemopause.  My poor little ovaries have been so confused since chemo started.  Now mind you, I am 56 1/2 years old and was stlll having very regular periods.  The funny thing about the period thing is that every doctor/nurse always asked me I was sure I was still having my periods.... like duh!!!!!  I also have taken pregnancy tests before every procedure/test.  You just have to laugh at that!!!!!  Hope you feel better soon soon soon!!! HUGS!!!!Cool
  • ljhm
    ljhm Member Posts: 60
    edited June 2012

    Thanks for everyones reply.  Am planning on cutting my hair and getting a wig to wear in public.

    ktb04  I think there is something in the chemo that makes you cry and weepy, my husband and son are getting used to it,  it makes me madder than it surprises them as I am a pretty tough chick lol and don't normally cry, then again that's probabaly why we are all still here!! Here's to touch ladies!

    ssj  A friend of mine also got the rash, scratches until it bleeds.  Call your onc.  He will probably increase your steroids but whatever works.  Steroids can cause a thrush infection in your mouth so try the gargle with 1/2 vinegar and water as well as whatever he prescribes.  Don't let thrush get out of hand as if can go down your esophagus.  Hang in there.

  • kltb04
    kltb04 Member Posts: 1,051
    edited June 2012

    Thanks Melrose and ljhm - Melrose, I hear ya on the pregnancy tests!  Things have been well, nonextistant in that dept lately so I had NO chance of being pg but everytime I went for a procedure when I was diagnosed, we had to go through the pg test thing!

    ljhm - I think there is something about Taxotere - I am far worse/more down than when I was on A/C and I have had others say the same thing.

  • RoulaG
    RoulaG Member Posts: 239
    edited June 2012

    I agree with you on the crying and sadness. My mood swings start on day three after chemo and last for three days. Everything from fear to anger very strange and extremely unsettling.

  • kltb04
    kltb04 Member Posts: 1,051
    edited June 2012

    I am on Celexa - just for about six weeks now - but I think I could have used some xanax on top of that right after first Taxotere TX...the celexa was prescribed more for my incessant worrying...

  • Hikergal
    Hikergal Member Posts: 74
    edited June 2012

    Thx Tazzy on the movie suggestions.  Do like the Monty Python, goofy but hilarious!  I have netflix and sometimes there isn't much but I really am in mood for comedies.

    kltb04 sorry to hear that you had some bad days.  I feel like a roller coaster of emotions too.  I am forcing myself to take a short walk (though it is Phoenix and HOT!) to hopefully get the endorphins to kick in.....

    I too, at 54 have been having regular periods. I was due last week but had chemo on Wednesday and haven't started.  Wondering if the chemo stopped it from happening.  Glad we are discussing it as my MO did not mention that I would go into chemopause.  Oh well, I start Tamoxifen in the fall and that will definitely put an end to periods.

  • ljhm
    ljhm Member Posts: 60
    edited June 2012

    I am also 54 and finished my periods 6 years ago,  went through menopause and the good news is that the chemo brought back menopause hot flashes and all :(.  It's not the cancer that's hard it's the drugs!

  • Melrosemelrose
    Melrosemelrose Member Posts: 3,018
    edited June 2012
    Hikergal:  Since I'm on that Herceptin clinical trial, i have to track my periods/lack of them for the next 3 years.  You might want to keep track of your and do what you have done which is figure out when it was supposed to me.  I can tell you I can feel those ovaries throbbing a little bit at times and I'm sure they are confused.  As for the hot flashes, I tolerate them.  They are no fun in the middle of the night.  I was telling one of my gal pals about the hot flashes so she told me to open up the freezer door and stand there to take in the cold air.  I told her the only problem with that is my almost bald just freezes!  What's a girl to do!!!!! LOL
  • KCB
    KCB Member Posts: 365
    edited June 2012

    Hi all! Some of yoh I know from other threads, but I am also on just Taxotere right now, so it's nice to share the journey. I am one week into my second, and have had different experiences each time.. Except for the crazy steroid high the first two days. Oh and the runs the first couple of days. The first round though I had muscle aches, wicked swollen glands and sore throat/neck/shoulders+tired. This round so far I have had more bone pain. Nothing crazy, but shooting pains in my legs, back even my head. Tylenol has helped all of it. Nastiest for me has been the mossy dry sandpaper mouth, can't really stand much but smoothies and yogurt and pudding.

    Had some tears last round. Oh, and pimples. Excellent. And... No more period.

    Hugs to all.

  • ljhm
    ljhm Member Posts: 60
    edited June 2012

    I turn ensure into smoothies, adds calories and helps my mouth.  Should look like Kojak by Friday, gotta shave my head tomorrow.

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