chemo before therepy

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shellybee
shellybee Member Posts: 2
edited June 2014 in Stage III Breast Cancer

i'm in stage 3 and I was advised as one of my options to do chemo to shrink lump and then surgery has anyone had this done? trying to decide if this is better option than a mastectomy help please im really trying to decide

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  • camillegal
    camillegal Member Posts: 16,882
    edited June 2012

    That's exactly what I had 4 months of chemo---Surgery, then back to chemo and herceptin. I think it works better for surgery cuz the size of the tumors are so big--I was fine with that decision-but the Drs. made it and I was still fine with their decision. I'm easy. I still had dble masectomy.

  • sherry67
    sherry67 Member Posts: 556
    edited June 2012

    I too had neoadjuvant chemo with the herceptin first for 4.5 months than surgery than more chemo than rads as well as continuing the rest of herceptin which I just finished 6/19 and have been taking tamoxifen also ..good luck







  • LuvRVing
    LuvRVing Member Posts: 4,516
    edited June 2012

    My oncologist gave me a choice and I opted for surgery first.  It seemed logical to me, to reduce the tumor load before chemo.  I was going for a BMX so shrinking the tumor before surgery wasn't a concern.  Getting the fast growing alien monster out of me was my main concern.  If you are considering a lumpectomy, then chemo first makes a lot of sense.

  • Dutchie
    Dutchie Member Posts: 112
    edited June 2012

    I was diagnosed at stage 3b and had chemo for 6 months before mastectomy followed by more chemo and Herceptin. It was extremely successful. For IBC (which I have) that is standard protocol. I know it sounds strange not to "get it out" right away but in some cases that is the riskier option. Good luck with your decision! If you have any more questions we're here for you.

  • lostinmo
    lostinmo Member Posts: 922
    edited June 2012

    I am having 4 months of chemo before surgery, the nice thing about it is being able to tell that the chemo is working. It won't change my surgery type but I can tell that the tumor has shrunk.

  • mary625
    mary625 Member Posts: 1,056
    edited June 2012

    I had chemo before surgery. With mine being ILC and a large tumor, I was not seeking to try to go for a lumpectomy. I already had a positive lymph node, so they wanted to treat me systemically as soon as possible. I was able to follow the progression of treatment and the shrinking of the tumor. By the time chemo was done, the tumor had shrunk from 7-10 cm to 1.8 cm, and the 2 cm lymph node was not even palpable. I still had 10 positive nodes at surgery, but onc said it probably would have been 25 without chemo. (This diagnosis came only 8 months after clean mammo and manual breast exam.

  • Dutchie
    Dutchie Member Posts: 112
    edited June 2012

    Mary625 (btw love your name because my birthday is 6/25!) I had an almost identical experience to you. I had 9-10 cm tumor hat shrank to 7 millimeters (!) and I had 18 positive nodes but just like you my onc said it would have been much worse. Nice to hear someone else had a good response to chemo first. All the best!

  • Momine
    Momine Member Posts: 7,859
    edited June 2012

    Mary and Dutchie, very similar for me. 6cm tumor (size varied depending on measuring method, but it was big) shrunk to 1.2 by 0.2 cm after 4 treatments with FEC. I had additional chemo after the surgery.

  • mary625
    mary625 Member Posts: 1,056
    edited June 2012

    Dutchie--our b'day is getting close! I hope you have a great birthday! It's a big birthday for me.

  • Dutchie
    Dutchie Member Posts: 112
    edited June 2012

    Happy Birthday Mary! I Was diagnosed at 39 and I am thrilled to be turning 44 Monday. Have a fantastic day and I wish you many more years of good health.

  • crazyride43
    crazyride43 Member Posts: 154
    edited June 2012

    Shellybee, all my specialists at Dana Farber really wanted me to try for breast conservation (lumpectomy) even though I had a 4cm+ tumor (MRI showed larger, ultrasound smaller...we'll never know for sure since it disappeared!).  I had dose dense A/C followed by Taxol.  After A/C the tumor had shrunk considerably, and after Taxol it was no longer visible on my pre-surgery MRI.  My breast surgeon ended up only taking tissue the size of a walnut, and i will know in a week or so about the final pathology.  I may still need a mastectomy if the margins are not clear, but I am glad i gave myself the chance to have the less invasive procedure.  Because of my age, tumor size etc, rads were always going to be in the picture event with mastectomy, so i figure why not save the breast if possible?

    When I was diagnosed, I didn't want chemo first, just wanted the cancer out of me as soon as possible.  Then my surgeon helped me understand that the systemic therapy was the most important thing to set in motion as soon as possible, plus we would be able to see if the chemo was working and change chemo types if it wasn't.  That's not possible once the tumor is gone.  She assured me there was no threat from the tumor growing / spreading once chemo was underway, and if there was any sign it was i would go immediately to surgery.

    I am now really, really glad i had chemo first.  Feeling the tumor shrinking after each treatment gave me the motivation I needed to get through some of the tough side effects of chemo.  I was also glad to have very little hair to worry about during recovery, so that's another bizarre silver lining!  Regardless of lumpectomy / mastectomy, i think getting the powerful medicine into you as soon as possible to start killing those cancer cells is important.

    Wishing you peace and a great outcome with whatever you decide.

  • ck55
    ck55 Member Posts: 346
    edited June 2012

    Mary625 - It is good to hear that the chemo (was it DD?) shrunk your tumor to that degree. I had ILC also and a large one at that (9 cm) but I had surgery first and then DD AC & Taxol. It seems I am always hearing that chemo doesn't work that well for ILC, but obviously that was not true in your case Laughing

    Make me hopeful that it may have gotten rid of any cells floating around out there at the time!

    Cyndi

  • jennyboog
    jennyboog Member Posts: 1,322
    edited June 2012

    That's what I did.  I had a large tumor and IBC, it was a reassurance seeing the IBC leave and feel my tumor soften/shrink.  They got clean margins at my BMX and everything went well.  Best wishes in tx and your decision.

  • mary625
    mary625 Member Posts: 1,056
    edited June 2012

    Yes, I had DD chemo.  I think there's someone in the ILC forum who had a complete response.  I was told that my response was excellent by my MO. 

  • kltb04
    kltb04 Member Posts: 1,051
    edited June 2012

    I am having chemo first as well - my BS/MO advocate neoadjuvant chemo not only to shrink the tumor but also so they can see what works as far as the chemo drugs etc...at halfway done, mine had shrunk from 3 cm to 1.6 cm but I am having a BMX regardless due to my age and other reasons.

  • faithfulheart
    faithfulheart Member Posts: 544
    edited June 2012

    It seems everyone had chemo first .  I on the other hand had my BMX first .  Accordig to my BS , it seems it was the best decsion for me.  They thought I had 1 Lymphnode,  I ended up having 10  , they would not have known that and possibly not teated me as agressivly.....However,  I have always wished I could have watched my tumor shrink so I knew my chemo was working...........I just have to trust God that it did its job getting all thoughs stray cells .They  did give me a choice, my MO told me that either decsion would not change my out come, I decided to get it out. I have a really high anxiety level, I don't know that I would have done well waiting...Good luck on your choice, you will do what is right for you I am sure...you will be in my prayers.

  • beegee
    beegee Member Posts: 32
    edited June 2012

    I had chemo first also.  Even though the chemo made me sick as a dog, it was worth it to see my tumor, which was growing outside my breast and into my chest wall, disappear.  After the first dose of chemo, there was a hugely noticeable difference!  I had one round of TAC, then three more rounds of TC. (I changed oncologists after the first treatment because I almost died from the first one.  New onc did not believe I needed the Adriamycin).  When I had the presurgery MRI there was nothing visible.  Surgery was a lumpectomy, and there was a 1mm cancerous area with positive margins.  Sentinel lymph nodes were negative!  I can't remember the size of the original tumor, but I could see it in the mirror, and there was some palpable under the skin area too.  She could not go in again, b/c of the location at my chest wall, so 35 radiation treatments followed the surgery.  Now I'm on arimidex.  The doctors were telling me that my response to the neoadjuvant chemo was "near complete."  I'm glad I did the chemo first because, as others have said, I could see the results.  

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