what kind of chemo?

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sandik
sandik Member Posts: 482

My surgery is over. Clean margins and nodes were negative! Yay! Friday I meet with my oncologist to discuss my chemo treatment. I was just wondering if there is a standard chemo for triple negatives? Does it change if you had negative nodes? How long and what types of chemo did you get?

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  • Titan
    Titan Member Posts: 2,956
    edited March 2012

    I had no nodes involved and clean margins...had 4 adriamycin/cytoxin and 4 taxol dose dense.....kinda aggressive treatment but for an aggressive cancer...

  • Luah
    Luah Member Posts: 1,541
    edited March 2012

    I had one node with micromets. I had 4 dose dense AC and 12 weekly taxol. I know some ladies here with smaller tumours and no node involvement have had TC. 

  • Sandlake
    Sandlake Member Posts: 211
    edited March 2012

    I had no nodes involved and clear margins...had 4 dose dense adriamycin/cytoxin everyother week.  Currently doing Taxol weekly #10 of 12 tomorrow.  Then will have rads for 61/2 weeks.  

  • sandik
    sandik Member Posts: 482
    edited March 2012

    Titan..what does dose dense mean? Were you sick? Or were you able to stay pretty normal with your routine?

    Question to all...port or no port. I am assuming Luah and Sandlake had a port since you went weekly for 12 weeks?

  • MicheleS
    MicheleS Member Posts: 937
    edited March 2012

    I did ACX4 dose dense. (Dose dense means every other week rather than every 3rd week.) Then, 12 weekly taxols.  I also got Avastin for 9 months.

    I had a port.  

  • lintrollerderby
    lintrollerderby Member Posts: 483
    edited March 2012

    Hi.

    I had clean margins and no node involvement. I did TC x 4 and had a port.

  • Kathy9433
    Kathy9433 Member Posts: 61
    edited March 2012

    Hi Sandik,

    I had lumpectomy...nodes were clear; margins were not.  Chemo was 4 AC every three weeks and 4 Taxotere every three weeks (just finished a week ago..YAY!!) Will be starting radiation for 5 or 6 weeks soon.  I say, Get the port.....it is SO much easier than searching for a vein every time....the nurses will LOVE you for it!!  God Luck to you...you can do this  OXOXOXOXOXO

    Kathy :O)

  • Titan
    Titan Member Posts: 2,956
    edited March 2012

    Sandi...dose dense is every 2 weeks...I was able to handle it pretty well...I worked through the chemo..but I have an office job...I was not sick and I did not have a port.

  • Morgan513
    Morgan513 Member Posts: 664
    edited March 2012

    I had 4 x TC, every 3 weeks.  Then radiation because I had a lumpectomy.

    Good luck!

    Lorrie 

  • Luah
    Luah Member Posts: 1,541
    edited March 2012

    With dose dense, you are given neulasta or neupogen shots so your white blood cells can recover in time for the next hit. Dose dense has been shown to be effective, though it's harder to take, it's also over sooner. 

    I worked throughout, I'm self-employed and work from home. 

    I had a PICC line (used more often in Canada than ports), and it worked out fine.  

  • sandik
    sandik Member Posts: 482
    edited March 2012

    Thanks ladies! I assume the neustela shots can't go in the port? :( I hate needles! Haha



    I hope to work through it. I am self employed. I'm a photographer, so it is a lot of office work. But when I'm shooting its rough. Especially weddings.

  • Titan
    Titan Member Posts: 2,956
    edited March 2012

    Sandi..sorry but the nuelasta is a shot..we are talking a needle here...everyone is different..I didnt handle the nuelasta very well for some reason..I felt like I had the 24 hour flu...for about 18 hours..does that make sense?  Not the pukey kind flu..more like the OMG..don't touch me type of flu.

    Anyway..if you are doing dose dense..and self-employed and work mostly on weekends you may try to schedule your chemos early in the week...by the time the weekend rolls around you should be good to go...I had chemo on Wed..and only felt a little icky on Fridays.  Good luck to YOU...

  • sandik
    sandik Member Posts: 482
    edited March 2012

    Thanks. I was thinking that. If Im down sick Tues, Wed or Thurs it's not that big of a deal, but weekends I have to be good. All these weddings were booked before diagnosis, so I have to do them. Hoping to have my daughter or her friend assist me though just in case. 

  • Hope60
    Hope60 Member Posts: 223
    edited March 2012

    Hi Sandi

    I had dose dense ACx 4, then Taxol x 4.  I had chemo on Mondays, started feeling icky on Wednesday, and didn't bounce back until Sunday or Monday.  But everyone reacts very differently.  After 1 or 2 treatments you'll probably have a good idea of how it will go for you.  Also I should mention that this was just for AC....I had almost no side effects from Taxol, just some fatigue.  Good luck to you!

  • Ericaalaine
    Ericaalaine Member Posts: 11
    edited March 2012

    Hi

    I was diagnoised Dec 10 with Triple Negative....2cm lump no nodes positive. I had the agressive chemo also to make sure it got anything possibly left. I remember the Dr. saying we have no way of knowing if we did it all for nothing. Which was a positive because the chemo was only a precautionary step. Also, I went 6 times every three weeks. I never felt nauseous...I had the chemo Thursday and that weekend I was usual spent. I felt more anxious or that I wanted to "crawl out of my skin". I would suggest Xanax, a heating pad (for muscle aches), and a hot bath!! I had radiation for 7 weeks after that. Best of Luck to you!!

  • Ericaalaine
    Ericaalaine Member Posts: 11
    edited March 2012

    Also,

    I am a teacher and worked the whole time. I just took a break here and there right after the treatment (usually Monday).

  • epgnyc
    epgnyc Member Posts: 101
    edited March 2012

    I've been diagnosed twice with Triple Negative.  The first was in 2002 and I had a 1.7 cm. tumor with no nodes.  I had 8 treatments with CMF (one every 3 weeks).  In 2011 I was diagnosed with a second TNBC but this one was much larger at 4 cm. with no nodes.  This time I had 4xAC and 4 Taxol, dose dense (every 2 weeks).  I had a hard time of it but that was just me.  Most people I know got through chemo without too many problems.  Best of luck to you...hope you do great!

  • sandik
    sandik Member Posts: 482
    edited March 2012

    Thanks guys. wow. Lots of different mixes. I guess there is no standard. I guess I'll find out on Friday. 

  • Merrinell
    Merrinell Member Posts: 46
    edited March 2012

    SandiK-I'm new here and I'm still learning more about this TN diagnosis.  My Onc team didn't really explain too much to me.  I began chemo on Feb. 7th taking Cytoxan, Neosar and Docetaxol.  I was given steroids to take the day before, day of and day after infusion, then I went and took that injection 24 hours after the infusion...but since they didn't tell me what it was, I'm assuming it was the Neulasta.  I was very ill by the third day, and was in ER twice during the weekend when  the nausea and diarrhea was overwhelming.  On the 8th day I was so dehydrated I had IV fluids for seven hours. 

    But here's the kicker!  I didn't find out until two weeks ago that everyone else who has these aggressive treatments got medications.  My oncologist gave me NOTHING.  I'm assuming he meant to but just failed to do it.  After talking to other patients at two different hospitals I was given the hint that I should have asked.  Why would I question my doctor's treatment plan?  I've never had cancer before.  I just assumed you have to be as sick as a dog! 

    I started losing my hair on the 13th day and started feeling better about the same time.  I began a new treatment on March 6th, this one is a 28-day cycle, for five cycles.  I take Cytoxan pills on Days 1-14, and take infusions of 5FU and Methrotexate on the 1st and 8th days.  This treatment has been much easier.  I was very nauseated at first, lost my appetite completely, but I found some Zofran the surgeon had given me after the mastectomy in January, and found that really helped.  When I went back to have my infusion on the 8th day, I asked my Onc for something for the nausea.  That's when he said "You should have plenty of refills."  My answer was "You have never given me any medications."  He looked shocked and went to the computer and although he discovered that he hadn't given me anything post-chemo, he never said a word to me. Just handed me a RX for Zofran with 6 refills.  Now with this treatment cycle, I have taken it faithfully and it has helped so much.  I still was queasy, no appetite, fatigued,  diarrhea, but after the 18th day I started feeling better.  I'm day 22 now, and the last four days have been almost normal.  My appetite is back.  I lost 18 pounds after the first chemo, but I could afford to lose those!  If I had been able to continue the first treatment plan, I would be finished April 10th.  Now I have to go to July 3rd.  Then I rest for a month and begin Rads 5X a week, for 4-6 weeks.   

    I'm not telling anyone this to make you more afraid of treatments.  Chemo stinks...no matter how you look at it.  But I have spoken to many survivors who tell me they had the treatments with very little problem.  Just be your own advocate.  Maybe if I had been less naive, I wouldn't be where I am right now.

     I am 72 years old, but I think I'm a pretty savvy lady.....not a senile Senior Citizen!  I still have a home-based business as I was a paralegal for over 30 years.  I live in a small town and during this down-sized economy, I still have attorneys who call on me to do small jobs for them.  I volunteer in a county-wide elementary school reading program (not right now...avoiding children and crowds), and I continue to be as active as I am able to.

    I just can't believe I didn't ask more questions.

  • Titan
    Titan Member Posts: 2,956
    edited March 2012

    Merri..excuse my french..but that is absolutely positively BULL**S**...you have to have EMEND..you shouldn't have had to ask..for gosh sakes...my oh my..I'm just freaking here..I just can't believe it...your onc OWES you big time...

    OMG..I'm still freaking....

  • onvacation
    onvacation Member Posts: 1,344
    edited March 2012

    so interesting the different mixes!  I am Triple Negative, no nodes, clear margins, stage 1 getting 6 rounds of T/C every 3 weeks followed by radiation.

     Merri - that is C-R-A-Z-Y how you were treated. So sorry you had to go through that.

      

  • Titan
    Titan Member Posts: 2,956
    edited March 2012

    Sorry I'm still freaking...but there is no way, no how anyone should be put through that he**..there is now way Merri should have to ask for this..how in the heck would she know...the onc should know..it is horribly wrong

    ok..deep breath here

    1)...IF your onc doesn't give you a script for EMEND and you are taking AC ASK about it..it is 3 three day pills..the first one is b-4 the treatment, then one the next day and one the day after that...the compazine is much milder and should be carried around with you on the 4th day..if you feel any type of twinge at all..take a pill...

    There is no way that people having chemo should go through what you did Merri..no reason at all....

  • sandik
    sandik Member Posts: 482
    edited March 2012

    OK thanks! My onco did say that I should not be sick. She said if i was then she isn't doing her job. Her mom had breast cancer, so I know she gets it. I'm going in Friday so I'll ask her what she's giving me for all the side effects as well.

    Sorry you had to go through that Merri!

  • Luah
    Luah Member Posts: 1,541
    edited March 2012

    Defitnely no reason to suffer through days of nausea anymore - plenty of good drugs.

    Sandik, I did dose dense AC and 12 taxol. I went Tuesdays, and felt well until Thursday, then a little fluish and tired for a couple of days. However, it was winter and I'm a passionate skier and I skied practically every weekend, so I can honestly say chemo didn't hold me back from much. I also walked and exercised throughout, and worked (from home - computer). The 12 taxol was much easier, I felt practically normal. I realize I got off pretty easy, and all women are different. You will just have to see how your body reacts. Maybe have a backup photographer who can step in? (I scouted for a writer who would do that for me, and I never ended up calling on her, thankfully.)    

  • borntosurvive
    borntosurvive Member Posts: 213
    edited March 2012

    I am just finishing my chemo (April 5th is my LAST!!!!).  I had no node and clear margins, double mastectomy.  I was given Dose Dense ACT.  Every other week for 8 rounds.  4 AC and 4 Taxol.  I also have the neulasta needle on Day 3 after chemo for my white cells.  My husband gives it to me (and he's no nurse!).  Not sure what my follow up will be - I'll find out on Wednesday next week when I see my MO pre chemo.  My counts got really low after my last AC so I had a blood transfusion.  Other then that I've been okay with my counts. 

    Good luck and keep us posted on how you're doing 

  • sandik
    sandik Member Posts: 482
    edited March 2012

    Thanks guys. Glad to hear so many of you did so well. Very encouraging! However, I was just at the radiologist and he was concerned about the 1mm margins because Im TN and only 40. He feels that the surgeon should go back in and clean it up a little bit more. Looks like the chemo show will have to wait for me now. 

  • Luah
    Luah Member Posts: 1,541
    edited March 2012

    Sandik: Good margins are a good thing! Makes sense to consult again with the BS and go for a re-excision if possible. For what it's worth, I had a close 1 mm margin on the inside, but because the surgeon had cut right to the chest wall, there wasn't much more she could do unfortunately... I got extra rads though and so far so good. 

  • LMT
    LMT Member Posts: 8
    edited March 2012

    I was on chemo at this time last year.  I had my chemo first--six rounds of Adriamycin, Taxotere, and Cytoxan.  Five weeks after chemo, I opted to have a bilateral mastectomy (my choice).  I didn't want to have to worry down the road about the other breast.  I have an excellent oncologist and surgeon.  I never had nausea after chemo--I got my anti-nausea drugs through the I.V. I never even needed to take Zofran.  I did not have a port, but my veins are damaged from the chemo.  A port might actually be better in the long run.  You will get through it all--my daughter got married right after my 4th chemo, and my son got married six weeks after my mastectomy.  I was there, wig and makeup on--cancer and treatments did not take that joy away from me! God bless you--you will come out the other side of this stronger, and capable of overcoming anything! Diagnosis 2-21-11 IDC 3 cm Node negative ER-/PR-/HER2-

  • red4sonja
    red4sonja Member Posts: 2
    edited March 2012

    Hi-- I am new to the site.  I had 4 A/c and 4 taxol, 2 weeks apart, which is still the gold standard treatment for TNC without nodes. With nodes sometimes more taxol or something else.    The neulasta is absolutely terrific and is what enables us to withstand treatment every two weeks without getting sick.  It is an easy shot in the leg; anyone can do it.  I did not have a port but it is an intramuscular shot, wouldn't go in port.  There is a lot of research on significantly improved survival rates with dose dense treatment, which was invented at sloan-kettering, where I was treated.  7 years now!

  • red4sonja
    red4sonja Member Posts: 2
    edited March 2012

    just wanted to say -- your veins get better, maybe not as good as new but much better,  my daughter got married and I was in a wig also.  I have 4 grandsons now (not all from her!)

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