Any grade 1 girls show response to chemo?

TectonicShift
TectonicShift Member Posts: 752
edited June 2014 in Stage III Breast Cancer

I'm having a mini meltdown tonight, worrying that the AC+T chemo I'm enduring right now isn't having any effect on my grade 1 cancer. I had surgery first so I'll never know. I'm looking for stories of people who had grade 1 tumors and neoadjuvant chemo and saw a response. Someone on this board did tell me her grade 1 turmor shrank quite a bit. So I know of at least one person. I'm looking for more stories to give me hope. Thanks.

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  • Anonymous
    Anonymous Member Posts: 1,376
    edited February 2012

    Hi Posy1.  I had AC+ T chemo also.  But not until after my surgery to remove 5.2 cm tumor and 18 lymphnodes 2 of then poitive for cancer cells.  My tumor was removed during mastectomy wiith clear marginm So I think it was really diminished by tge time chemo affecr it .  I like  to thinkd  \hata throufhing everinthing but the kitchen sind  After cheno radiatino ian the next treatment      itrls prtty f  

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    BARB

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  • lamuso
    lamuso Member Posts: 123
    edited February 2012

    My Grade 1 tumor shrank from 5 cm to 2 cm.  Don't assume the chemo isn't helping you.  My oncologist and surgeon were both very pleased with my results even though I didn't have a total response I had a pretty good one.  It gave the option of having a lumpectomy even though I still choose mastectomy.  I had one lymph node positive before chemo so we were really going for tumor shrinkage.

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  • MaxineO
    MaxineO Member Posts: 555
    edited February 2012

    Posy: I have similar 'what-if' scenarios run through my head. I didn't have neoadjuvant either, but like Barb says, they definitely do a multi-faceted treatment for stage 3: chemo and rads and hormone therapy (and more?), figuring one of those or all of those will do the trick.  Remember AC+T is potent stuff...I don't think they would put women with grade 1 tumors through the treatment if they didn't think (or know!) it worked.

    Best wishes for you through chemo. I still can't even look at red kool-aid without feeling nauseous, thanks to the adriamycin!

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  • mamabee
    mamabee Member Posts: 546
    edited February 2012

    I'm in the middle of neoadjuvant chemo (TACx6) and my tumor is low grade 2 (Nottingham=6). I also had a Mammaprint test done which came out low risk and supposedly (according to a couple of studies) I shouldn't have much response to chemo. But I have had a very good response so far after 3 treatments - my MO estimates my 3.5 cm tumor has shrunk by more than half. Hope this makes you feel better - good luck with the rest of your treatment!

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  • AnacortesGirl
    AnacortesGirl Member Posts: 1,758
    edited February 2012

    One way or another, it's going to be fine.  I was grade 3, done my research and found that grade 3 is more responsive to chemo.  Well, there was some minor shrinkage but not much.  So the results of my chemo were "no response".  But I had surgery and rads.  Almost two years out from surgery and I'm still NED.  I'm very grateful that we have a 4 pronged tx with chemo, surgery, rads and hormonals.

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  • karen1956
    karen1956 Member Posts: 6,503
    edited February 2012

    Wish I could help....my Tx protocol was bilat Mx, TAC chemo x6, rads, AI's and ooph....I am 6 years post Dx....I see my onc for 6 month check up next month...As far as I know I am still dancing with NED.....

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