Oophorectomy - just throwing it out there!

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tuffgirl
tuffgirl Member Posts: 63

Hi all

As this I consider pretty much my most dependable sounding board! well here it is. I am now 50. Shocker after 3 years 10 months post chemopause I am now firmly premenopausal having periods, super high estradiol, low FSH etc. scans all normal  biopsy of uterus normal. so...

I am as you can see below i was ER+ PR+. I started on Tam until we thought I was firmly post m and went on letrozole. I know this is a personal decision etc. but I would really like something to think about on this option and respect everyone's thoughts here.  An ooph and rid of the tubes (uterus can wait) is one option for me with the letrozole.  Right now I am back on Tam. I see my onc next month because he keeps getting bloodwork and checking that the Tam is going okay.

I should add that I was, I guess you call it only quasi aggressive in that I only had a uni mast not a bmx.  But I did do DD have been on zometa.

I guess the down side is having to go through menopause all over again and depression ( got depressed on the Tamoxifen before i went back to premnopausal but that was solved by the letrozole - but a recurrence would obviously be beyond depressing!!

Anyway just throwing it out there and if anyone is worried a firestorm will ensue or you are shy (I am) please feel free to pm me. take care all

Comments

  • toomuch
    toomuch Member Posts: 901
    edited January 2012

    canadianmum - I had my tubes and ovaries out from the start, just so I could go on AIs. My MO thought that Tamoxifen would be ok but after doing some research myself, I wanted the AIs. A gyn/onc thought it was reasonable with my FH so out they came. It's a personal choice. All that really matters is that you sleep well at night. Good luck making your decision!

  • Angelfalls
    Angelfalls Member Posts: 849
    edited January 2012

    I had an ooph at 35 when Tamoxifen stopped working for me. This meant I could reduce the amount of oestrogen trying to kill me (!!!) and start with an AI. I could also have gone for a chemically induced menopause, which may be another option for you? You just have to go with what feels right for you. Good luck with your decision, whatever that may be, Angelfalls xx

  • elfling811
    elfling811 Member Posts: 1
    edited January 2012

    I have been on the Tamoxifen since Nov. 2010 and for the last 3 months or so, my periods have slowly been coming back.  My MO and GYN are letting me make the final decision as to taking them out.  I am finding more articles online that make me want to have them out.  There is an increased risk for cardiovascular disease following an ooph, but that doesn't scare me as much as the possibility of my cancer coming back a third time does.  At the end of the day, though, the decision is for each woman to make for herself.  *hugs* to you while you make this decision....I know that I am struggling with it too.....you are totally not alone in this!

  • karen1956
    karen1956 Member Posts: 6,503
    edited January 2012

    I had an ooph as part of my Tx protocol....chemo stopped my periods....then after chemo shot of Lupron then a couple months later had ooph....my onc didn't think my periods would come back (I was 50) but you never know....for me it was one less thing to worry about having my ovaries out....but there are draw backs to be thrown into instant menopause.....tamox is still a good med....if you are doing well on tamox take your time to decide which way you want to go.....

  • B123
    B123 Member Posts: 730
    edited January 2012

    Tamox didnt do well for me, bad SE with it so I stopped.  But being highly ER/PR+ I need to do something to stop the estrogen so I begin Lupron shots this week monthly until I am ready to take out my ovaries.  My BMX exchange is scheduled for Feb 9 then I will do my Ooph beginning March.  It is easier in the long run and one less thing to worry about (and I think its a big thing since its the route of the cause).  I may even have a full hysterectomy just in case I end up on a med that may cause End cancer... last thing anyone of us need.  Good luck, not an easy decision to make!.. by the way Im 42

  • Kay_G
    Kay_G Member Posts: 3,345
    edited January 2012

    I know how you feel. I just turned 49 and started on tamoxifen. I would rather be on an AI with the uterine cancer risk, but onc said I was premenopausal and periods could come back even years later. I haven't had one since chemo started in April. I thought she was crazy, I guess not. But I don't really want to go thru an ooph with the thought that I'll be menopausal soon any way if I'm not already. It feels like we're between a rock and a hard place. Good luck with your decision. I think if they offered to do the ooph to me, I'd do it. I am really scared of the uterine cancer with tamoxifen.

  • Fearless_One
    Fearless_One Member Posts: 3,300
    edited January 2012

    I had hyster and ooph and so far it has been pretty uneventful.   I had it done robotically and was back to work in 3 weeks, too.    I was afraid of both uterine and ovarian cancer.

  • B123
    B123 Member Posts: 730
    edited January 2012

    Kay1963: Im glad you dont have to do it and things are moving along for you.. one thing at a time!  I wish the Tamox worked for me..

    Fearless: You had both done and you have been fine?? Any hot flashes, moodswings, severe pain?? Are you on any meds to help with that?  Im afraid of both cancers as well, I want to just do the ovaries but am afraid to stop there and then live with, what if??

  • vacationbound
    vacationbound Member Posts: 171
    edited July 2012

    I have only been on Tami for 5 months, Since Dec 1, I have been bleeding every day. I had an Ultarsound done and I go next week for results. The tech said my Uterine lining was "Prominent". I believe the Tami has stopped working. Hopefully I can cross to the other side for more treatment options. This is not only my hope but my prayer!

  • B123
    B123 Member Posts: 730
    edited January 2012

    vacationbound, sorry to hear all of that.  I also did not do well on Tami and stopped it after one month.  I am now doing Lupron and once Menap is established will go on an AI, I just hope one of those works for me and is not as harsh as Tami.  I dont think I can take anymore.  Big hugs to you my friend, hope you have luck on finding the right med to work for you as well!!

  • Racy
    Racy Member Posts: 2,651
    edited January 2012

    Kay1963, I am also 49 and was premenopausal before chemo but periods stopped the day chemo started. At the end of chemo I had my hormone levels tested and the onc said they were in the menopausal range and prescribed an AI, Femara.



    I'm just mentioning this in case you want to get your hormone levels checked.

  • AnacortesGirl
    AnacortesGirl Member Posts: 1,758
    edited January 2012

    I just turned 50 when I started chemo.  Had one period and that was the end of them.  Even though I did the bilateral, I went ahead with an ooph because of the BRCA2+.  I think I would have wanted one anyway.  My cancer was 98% ER+ and I wanted to get rid of it's "food"!  I didn't do a hyster because I've never had any issues, wanted to maintain the structure down there, and since I'm being monitored closely it will be easy enough to have done in the future if it's needed.  My maternal aunt died from cervical cancer and my mom had issues with fibroids so she had a hyster.  I'm more concerned about taking care of what I did have.

    I was put on Aromasin but the SEs were unbearable for me.  So my onc changed me to Tamoxifen.  In another year we'll probably try switching to Femara or Arimidex.  But I'm not anxious to get on an AI again after the Aromasin experience.

    Depression would be a real concern for me if you've already experienced it when your estrogen fell off during treatment.  Did your doc give you an anti-depressant?  When I was on Aromasin I was using Paxil but that interfers with Tamox so I had to switch.  Boy, that was rough!  If I ever had doubts about whether or not the anti-depressant was working, those two months convinced me!  The first month was weaning off the Paxil.  Then it took me 4 full weeks for the Lexapro to kick in.  I hit some real rought spots in there.

  • ALittleBitBritish
    ALittleBitBritish Member Posts: 627
    edited January 2012

    I have been on Tamox since May 2011, and now my early January US showed cysts, polyp and thickening of endometrial lining, can't see a Gyn till mid next month.

    My doc just told me to pick up my results so no-one had discussed this with me. My MO didn't go into any details of what this means......I guess maybe heading towards a hysterectomy...who knows, doing my own research...thinking Da Vinci robotic..I blame tamox as no issues before..the joys of cancer!!Yell

  • marilyn113
    marilyn113 Member Posts: 118
    edited January 2012

    I'm 52 and see my MO on Wednesday.  They've been talking about putting me on Tamoxifen, but I have high triglycerides, so I don't think that's a good idea.  I plan to ask about having an ooph.  I'm very ER+ and so close to menopause it just makes sense to remove the major source of estrogen.

  • Menasu68
    Menasu68 Member Posts: 1
    edited February 2012

    I was diagnosed in 2010. I am 43. Had chemo, double mastectomy, more chemo and radiation. Started on Tamoxifen but my period came back about a year after my diagnosis, so I had the oophorectomy and a hysterectomy and now I am on Arimidex. The menopause symptoms were really mild. I also had it done with a robot and my recuperation time was really good, back to "normal" in about 3 weeks. The peace of mind for me is priceless... One less cancer recurrence to worry about! :) Good luck with whatever you choose.

  • tuffgirl
    tuffgirl Member Posts: 63
    edited February 2012

    Hi everyone and thanks for responding ! i have another month to think because my appointment had to be switched. But the comments about depression have really hit home. I'd like to go on an anti depressant but my only close pal on them who works in my same field has told me it really makes it difficult for her to think sometimes so I'm scared to death of them. THAT's really my only hold back. I  just had no problems at all on the letrozole weirdly just the tamoxifen. I just don't want to be accomodated or anything. My pal had to ask for that and be placed in a lesser stress but also lesser fun job. thanks all

  • Kay_G
    Kay_G Member Posts: 3,345
    edited February 2012

    Seeing an ObGyn today. Yuck! Will see what she says, recommends and let you know. I just turned 49 and haven't had a period since chemo in April.

  • AnacortesGirl
    AnacortesGirl Member Posts: 1,758
    edited February 2012

    I attribute my problems with thinking to chemo brain.  The positive attitude I get from the anti-depressants definitely outweighs any negative effects on my thinking.

  • Cat123
    Cat123 Member Posts: 296
    edited February 2012

    Saying hello from Toronto!  I thought about the oopmh but didn't have one.

  • vacationbound
    vacationbound Member Posts: 171
    edited July 2012

    They took me off Tamoxifen as it was acting like an estrogen in my womb. I had a clear clean a and pelvic in Aug 2011, then in Jan 2012, they found a cervical polyp, an ovarian cyst and a uterine lining thickness of 10MM (not supose to be bigger than 5 MM) so even though the biopsies came back negative, my Gyno/Onco said she would not do a preventative Oopertectomy so I am goingto have my Estrogen levels tested to see how close I am to natural menopause.

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