Aromatase Inhibitors without SEs?

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Wren44
Wren44 Member Posts: 8,585

Are there women taking aromatase inhibitors who are not experiencing horrific side effects? I have to decide whether to try them or not. My onc highly recommends I do, of course.

Comments

  • chrissyb
    chrissyb Member Posts: 16,818
    edited January 2012

    Hi Wren, I guess I'm one of those who don't have horrific SE's from Femara but I did when I was on Arimidex.  They are all different just as we are all different and the only way to know if you are going to have the SE's is to try the drugs.  If one is too difficult to deal with, change and try one of the others, you may be like me and find the first harsh and the second pretty much a breeze.

    Love n hugs.  Chrissy

  • ptdreamers
    ptdreamers Member Posts: 1,080
    edited January 2012

    Wren, ChrissyB is right. You need to try and see how it works. also the time of day you take it may make a difference. I take mine after the evening meal. I have only been on for alittle over three weeks but so far so good.

  • Wren44
    Wren44 Member Posts: 8,585
    edited January 2012
  • Pompeed
    Pompeed Member Posts: 239
    edited February 2012

    Calling the oncologist tomorrow. 

    Just threw mine down the john.

    Just as bad -- if not worse -- than Tamox. 

    Done, done and done.  With the damn drugs and the damn statistics too.

  • pupmom
    pupmom Member Posts: 5,068
    edited February 2012

    I have no SEs. I've been on Aromasin for about six weeks. Sometimes I wish I would have a SE. Kind of wonder if it's working. I know it is, but still would be nice if it let its presence be known, just a little bit.

  • SuperFoob
    SuperFoob Member Posts: 505
    edited February 2012

    I have been taking letrozole (generic Femara) for one month. No side effects. I take it at bedtime.

    Interestingly, hot flashes are supposedly the number one side effect but my hot flashes have subsided for the most part. I have had one hot flash in the last week.

    I started getting them during chemo (chemopause-last chemo 10/06/11) and they continued after my Oophorectomy (11/03/11). No better, no worse. Now, they are pretty much gone.

    I. Don't think the letrozole has anything to do with it but who knows.

    Just like chemo and everything else...everyone is different.

  • Sandeeonherown
    Sandeeonherown Member Posts: 1,946
    edited February 2012

    pompeed- i did the same in december...told my breast surgeon but not my oncologst....guess i should do that. I don't want to try another one...i am tired of feeling like my body is not my own...

  • toomuch
    toomuch Member Posts: 901
    edited February 2012

    I've been on Arimidex for a year.  Initially I had mild hot flashes but I haven't had them in a few months. I take mine at bedtime. I do feel stiff in the morning but after I move around a bit, the stiffness goes away. I sometimes have joint pain but it's pretty mild and I rarely have to take anything for pain. So, I have some SE's but none severe enough that I considered stopping the Arimidex. You can always change drugs or stop altogether if you have severe SE's but you may be lucky!

  • lago
    lago Member Posts: 17,186
    edited February 2012

    Me. I've been on Anastrozole (generic Armidex) since March 1, 2011. I get some stiffness in my fingers and toes in the morning but once I get moving it's fine. Some day I do notice it a bit more. Usually when it's really cold and damp out. Today it was in the 50's and I felt fine.

    I dont' have hot flashes. I did have them on chemo but only between 2am & 5am and never sweaty, just hot. They seemed to go away by the time I started the AL.

  • Claire_in_Seattle
    Claire_in_Seattle Member Posts: 4,570
    edited February 2012

    Almost two years into anastrazole, I am just fine.  I may be a BIT achier, but hard to tell as I always push myself exercising.  For example, I cycled 60 miles this past weekend, getting soaked on Sunday.

    I look and feel great. True, I could stand to lose 10 lb, but I have not gained weight.  (Gluttony is more the reason I don't lose.)

    I sleep well, and eat more or less what I please.  That said, I eat an overall healthy diet.  My brain is in top condition.  I believe I am on top of my game.

    So the answer is that you just don't know.  Some women are deathly ill.  I am just fine.

    On the other hand, I can't take cold medications without feeling like I am crawling out of my skin.  So I go the "tea and aspirin" route whenever I get whatever's going around.

    You need to find out for yourself.  I don't think any one of us can tell you.  Good luck. - Claire

  • Elizabeth1889
    Elizabeth1889 Member Posts: 1,036
    edited February 2012

    I have been taking anastrozole for four months and have had very few side effects and those have not been bad.  My main problems have been a bit of achiness in my left wrist when I awaken and the opposite of hot flashes.  I now need a warmer temperature to feel comfortable.  So far, I really cannot complain.

  • Moderators
    Moderators Member Posts: 25,912
    edited February 2012

    Wren, as well as the personal experiences here, there is information about Aromatase Inhibitors at the main Breastcancer.org site.

    The info on the site ends with "If you're experiencing side effects from taking one aromatase inhibitor medicine, tell your doctor. You may be able to take a different medicine. Arimidex and Femara have similar chemical structures, while Aromasin has a different structure."

    Judith and the Mods

  • ibcmets
    ibcmets Member Posts: 4,286
    edited February 2012

    Thanks Judith,

    That's good news.  Thank you for popping in on the threads to help direct us to the answers we are all looking for.  I've been on this site for over 2 years and this is the best site for help and information.

    Terri

  • kathy1925
    kathy1925 Member Posts: 34
    edited February 2012

    Hi! I've been on generic Arimidex for 18 months and have little or no side effects.

  • dogsandjogs
    dogsandjogs Member Posts: 1,907
    edited February 2012

    I had no side effects, other than hot flashes until after 3 months. Then I got bone pain in toes, hips, shoulders and knees, very bad depression, constant hunger and tiredness.  Am just re-starting after a 6 week lay-off hoping the SE's will be less this time

  • RoseR29186
    RoseR29186 Member Posts: 13
    edited February 2012

    My oncologist started me on Femara. Lasted 6 months before I couldn't take the joint pain any more. She switched me to Aromasin and I just completed the additional 4-1/2 years. Everyone's different, but my side effects on Aromasin were minimal in comparison and manageable (minor joint pain but extreme vaginal dryness). Anxious to see what, if any changes I'll see now that I've completed the regimen.

  • di1947
    di1947 Member Posts: 13
    edited February 2012

    I have been taking 2.5 mg a day of letrozole(femara) for 2 weeks, after getting an oncotype score of 8. I have not had any side effects so far, but I do take 5000 iu of Vitamin D3 a day. I take it before I go to bed and sleep through the night. I asked my MO when SE should kick in, and he said right away. I just turned 65 years old and my medicare blueadvantage cost for a month of femara, was $7.

  • exbrnxgrl
    exbrnxgrl Member Posts: 12,424
    edited February 2012

    Almost 3 months of generic Arimidex. Some morning stiffness and achiness if I sit around too much but not even close to horrific. I do exercise almost daily and I am on my feet at work all day. I drink lots of water and maintain a pretty healthy diet. Everyone is so different!

    Caryn

    PS: some of the AM stiffness could be aging!

  • ruthbru
    ruthbru Member Posts: 57,235
    edited February 2012

    I've been on Arimidex 4 1/2 years. I am fine. I was a little achy and 'hot' at first, but kept exercising and everything settled down pretty fast. I have been so grateful to have something I could do to greatly lower my risk of recurrence.....few SEs could be as bad as dealing with cancer!! Go into it with an open mind. It is just natural that people who have difficulties are the ones talking about it. Everyone else is just out living their lives. Best of luck! Ruth

  • exbrnxgrl
    exbrnxgrl Member Posts: 12,424
    edited February 2012

    I agree with Ruth. You are far more likely to find those who are having bad se's talking and posting about it.

    Caryn

  • Vicks1960
    Vicks1960 Member Posts: 473
    edited February 2012

    I have been on Letrozole (generic Femara) since November 21, 2011.  Have had some hot flashes, and am having some aches but nothing I can't handle so far.  It will be worth it if it can reduce the chance of recurrance..

    Vickie

  • tuffgirl
    tuffgirl Member Posts: 63
    edited February 2012

    Hi  like Vickie I was on letrozole for years - no SEs apart from ongoing chemopause.  It was fine! good luck

  • LoveLau
    LoveLau Member Posts: 105
    edited July 2018

    cant any one do a study on people who are taking

    Aromatase inhibitirs and have suicide thoughts. There must be a solution. I am on anti depressants and anti anxiety pills and at night I think if my husband dies, I will kill myself. Nothing wrong with my husband. I am trying to pull myself out but cant do it tried all if them. There must be some solution. The only solution I have been offered I'd electric convulsive therapy and possibly ketamine. Some one must have figured out a solution. This is not living. A out the only thing I like to do is to sleep.

  • Moderators
    Moderators Member Posts: 25,912
    edited July 2018

    Dear LoveLau,

    We are so very sorry that you are still struggling with depression and suicidal thoughts. Our thoughts are with you. We hear that you are not interested in the ECT and wondering what other options your psychiatrist has offered. Please talk to your doctors and your family so that they can support you through all of this. This particular thread is very old with no recent activity. You have previously posted on your struggles in the thread that you started on Depression . You received a good deal of support there from others. Please pm us also so we can support you. The MOds

  • dtad
    dtad Member Posts: 2,323
    edited July 2018

    LoveLau...here if you need me. IMO you should consider ECT. You have to have some QOL!

  • BikerChik
    BikerChik Member Posts: 4
    edited April 2019

    Hi Wren44,


    I am 53 years old- I run on the treadmill about 30 miles a week and ride my bike to work everyday (about 100 miles a week). I have 2 teenagers who keep me going to functions all the time. I say all of this because I think your activity level is key to lessening the SE of AIs. I am on Arimidex and have had no problems. I have only been taking it for 5 weeks so SEs could set in at anytime but I am hopeful I can make the 5 year mark.

    I was pretty petrified to start taking the Arimidex because all of the negitive I had head but you don't know until you try it. There is a thread for those of us doing well in AIs. Check it out.

  • cassiecanada
    cassiecanada Member Posts: 166
    edited April 2019

    hey biker chick-

    i, too, have decided to give the pills

    a shot. ( femara, for me ...63 yrs)

    i still roadbike like crazy-60 km aday in good

    weather and my big fear was losing

    my main joy- but as you so rightly point out,

    perhaps it will minimize the side effects...

    perhaps i should just try and see for myself.

    I had myself in an early grave after reading

    all the debilitating side effects

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