Taxol shortage mean Taxotere

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Seabrook
Seabrook Member Posts: 13

I met with the medical oncologist yesterday. My chemo regime will be AC every two weeks for 4 cycles. Then 4 rounds of Taxotere once every 3 weeks. Normally, the regime would have been Taxol every week for 12 weeks. However, due to a shortage of Taxol, I will be doing the Taxotere. If I can't tolerate the Taxotere, I will then be switched to Taxol. Now I am very nervous about the side effects of the Taxotere since it can only be given once every 3 weeks. Has anyone had experience with Taxotere? Has anyone else been affected by this shortage of Taxol?

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  • Awaywego
    Awaywego Member Posts: 16
    edited September 2011

    Seabrook, I was diagnosed 1.5 yrs ago and was treated with 3 rounds of AC 2 weeks apart and 3 rounds of taxotere 3 weeks apart. I have similar stats as you, <1cm. I found the taxotere to be much more tolerable than AC. With AC I had side effects immediately (nauseau, weekness). The side effects from taxotere hit me about 5 days post chemo and mainly consisted of flu-ish aches and pains. These aches were not intolerable. My hair even started to grow back on taxotere. My Onc avoided taxol as he felt the risk of neuropathy was greater however he did mention that taxotere was harder on "the bloods". I believe he meant it may be a bit harder for my counts to bounce back after each treatment. I had no issues though and this certaintly isn't a second rate drug. I know everyone tolerates drugs differently but I did well and I hope you will too. </p>

  • Awaywego
    Awaywego Member Posts: 16
    edited September 2011

    Seabrook, I was diagnosed 1.5 yrs ago and was treated with 3 rounds of AC 2 weeks apart and 3 rounds of taxotere 3 weeks apart. I have similar stats as you, <1cm. I found the taxotere to be much more tolerable than AC. With AC I had side effects immediately (nauseau, weekness). The side effects from taxotere hit me about 5 days post chemo and mainly consisted of flu-ish aches and pains. These aches were not intolerable. My hair even started to grow back on taxotere. My Onc avoided taxol as he felt the risk of neuropathy was greater however he did mention that taxotere was harder on "the bloods". I believe he meant it may be a bit harder for my counts to bounce back after each treatment. I had no issues though and this certaintly isn't a second rate drug. I know everyone tolerates drugs differently but I did well and I hope you will too. </p>

  • Awaywego
    Awaywego Member Posts: 16
    edited September 2011

    Seabrook, I was diagnosed 1.5 years ago with similar stats as you but no nodes, 7mm IDC. I was treated with 3 rounds of AC 2 weeks apart and 3 rounds taxotere 3 weeks apart. I did much better with taxotere than AC. With AC I felt nauseous and weak within a few hours after chemo. This lasted for about 2-4 days. With taxotere, the side effects hit me later, about day 5 post chemo. I mainly had body aches that were not severe. Given my particular stats, my Onc avoided taxol as he thought the risk of neuropathy was greater. He did mention however, that taxotere is "harder on the bloods". I believe he was referring to the body's ability to bounce back from a blood count perspective after each chemo treatment. Taxotere is certainly not a second rate drug so I wouldn't worry to much about the taxol shortage. I know everyone tolerates drugs differently but I did well with taxotere and I hope you do too. My hair even started growing back while on this chemo. Best of luck to you!

  • CoolBreeze
    CoolBreeze Member Posts: 4,668
    edited September 2011

    I've done both and the taxotere was easier.  You have three weeks to recover (although there wasn't much to recover from) unlike the taxol, which just keeps coming and coming.  :)  Drink lots of water and you'll do fine.

  • Seabrook
    Seabrook Member Posts: 13
    edited September 2011

    Thank you so much for sharing your experiences. I am feeling much better!

  • mrsnjband
    mrsnjband Member Posts: 1,409
    edited September 2011

    I would disagree.  I thought that Taxol was much easier than Taxotere,  Taxotere made me dizzy, nauseaus, more neuropathy. With Taxol I just had the neuropathy.  That is my opinion. NJ

  • yellowdoglady
    yellowdoglady Member Posts: 349
    edited October 2011

    I did taxotere every three weeks for six rounds and it was not tragic.  Yes, a few days later you feel like shit, but that is mostly a given with chemo.  I had no dizziness.  Only nausea at the last two doses, and that was expected.  No neuropathy.

    The worst side effect was that I gained a good 10-15 pounds after I finished treatment.  While you are in treatment you are told to EAT!  PLEASE EAT!  That is good advice when you are losing weight by the week.  After, it's hard to get back to a regular diet because you have had a free pass at eating for months.  Don't worry, it can be done.       

  • LuvRVing
    LuvRVing Member Posts: 4,516
    edited October 2011

    Seabrook - many women are being given Abraxane instead of Taxol or Taxotere, due to the Taxol shortage.  It can be administered weekly.  Ask your MO if it would be right for you.  It requires a whole lot less pre-medication and is equally, if not more, effective.  It is expensive, but if your insurance doesn't care, then Abraxane might be a good option. 

    Michelle

  • Kay_G
    Kay_G Member Posts: 3,345
    edited October 2011

    I started on Taxol, but got pnuemonitis from it (am allergic to it).  Switched to taxotere every three weeks after one Taxol.  I thought the Taxotere was easier than AC and also easier than the Taxol.  I had less nueropathy on Taxotere than Taxol.  The pnuemonitis was the other reason it was easier.  Good luck. 

  • stephanie82510
    stephanie82510 Member Posts: 30
    edited October 2011

    I convinced my MO that I should do TAC, not just two of the three available. In hindsight, with a diagnosis of Stage IIIC, I have peace of mind a year later. I did have Taxotere and the side effects of the Neulasta shot were definitely what bothered me. I rolled right into 37 treatments of radiation and again, it was worth the fight with my RO to get that many. Your MO should be giving you pre-treatment for nausea before the chemo starts. I chose not to take all of the steroids they recommend and in the second and third weeks of the three week cycle, I made sure I went for a long exercise walk a few days a week.  Note: You cannot touch children under the age of 12 for the first 72 hours after treatment (expecially with the red one). These drugs are exiting our body and children who have not completed all of their shots should not be touched by us.

  • Luah
    Luah Member Posts: 1,541
    edited October 2011

    Stephanie, just wondering where you heard about not touching children for 72 hours after chemo? I have never heard of that, and it wasn't in any drug sheets I received. I ask because there are plenty of women here in treatment with young children who may feel anxious... and I can't understand what viral inoculations have to do with drugs "exiting our bodies."

  • Fighter_34
    Fighter_34 Member Posts: 834
    edited October 2011

    Yes, please update us because I have very young kids and I touched them all during treatment.

  • mccrimmon324
    mccrimmon324 Member Posts: 1,076
    edited October 2011

    For you ladies wondering about the 72 hours, I know when I started treatment TAC - we asked the nurse and she said that we should be fine, the only thing that I really should do is double flush the toilet after use for the first 48 hours.  We don't have children though, my husband and I just asked for ourselves and then we have dogs. 

  • Meggy
    Meggy Member Posts: 530
    edited October 2011

    I thought Taxol as a breaze....why is there a shortage.  This really makes me mad. 

    So I just read that the shortage is different from one part of the country to antoher and that larger institutions reported no shortage at all because they ahve multiple suppliers.  The drug companies make me so dang mad.  What the heck...they said a bunch of drugs are in short supply...what is their problem?

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