holistic alternatives to tamoxifen?

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ej01
ej01 Member Posts: 155

I was diagnosed with DCIS about a month ago.   My DCIS was detected very early and was very small (they think it may have all been removed with biopsy). MRI showed not additional suspicious areas.  I will be getting a lumpectomy.   I will wait to see what my margin analysis is and meet with the radiation doctor to decide about getting radiation.   I really do not want to take tamoxifen, but it seems like it is recommended for almost all DCIS patients in my agegroup (49).   Has anyone found an oncologist that gave you  a holistic alternative to tamoxifen?  If so, what did the holistic approach entail? 

Comments

  • heavenschild
    heavenschild Member Posts: 212
    edited August 2011

    I am also looking for a holistic approach.  The S/E for Armidex (the other estrogen supressing drug) is uterine CANCER, hello!  The Armidex made my joints ache terribly and I had horrible moods.  I am now taking flax seed oil, but would really welcome any/all recommendations.  Blessings! 

  • cycle-path
    cycle-path Member Posts: 1,502
    edited August 2011

    Did you ladies check out the holistic and alternative sections here? I haven't, but if there's a holistic alternative I suspect those folks would know about it.

  • echosg
    echosg Member Posts: 12
    edited August 2011

    Research Calcium D-Glucarate and Indole 3.  Look at eating an anti-estrogenic diet.

  • Chocolaterocks
    Chocolaterocks Member Posts: 364
    edited August 2011

    hi- I am taking

    1 pill 200mg of inderol carbinate ( similiar to dim) daily and the rx I am on is 1000mg of Metformin.

    I had problems on tami and fareston and I am pre- menopausal and want to do everything I can..

    I also take fish oil, 3000 mg of D3 daily, multivitamin, grapeseed extract, .....

      I will research calcioum d- glucarate also.

    always looking for ideas.

    take care

    Chocolate Rocks

  • otter
    otter Member Posts: 6,099
    edited August 2011

    otter butting in here, on a forum where she doesn't belong...

    Re:  "The S/E for Armidex (the other estrogen supressing drug) is uterine CANCER, hello!"

    Just to keep the record straight:

    There are three "estrogen-suppressing" drugs in common use these days -- Arimidex, Femara, and Aromasin.  None of them has uterine cancer as a side effect.  There are other, serious problems associated with those drugs, all of which are "aromatase inhibitors," but one thing you don't have to worry about is uterine cancer.

    Tamoxifen, which is not an estrogen-suppressing drug (tamoxifen is a "SERM" = selective estrogen receptor modulator), does have uterine cancer as one of its most serious SE's.  The risk of uterine cancer is a little bit less with Evista, the other widely used SERM; but it's still higher than with the 3 aromatase inhibitors.

    Anyone interested in a holistic approach to all this might want to stop by the 2 relevant forums in the "Treatment" section of the boards.  One deals with complementary and holistic approaches (things used in addition to conventional treatment); the other deals with "alternative" approaches (things used instead of conventional treatment).  Both are very active forums.

    otter

  • ej01
    ej01 Member Posts: 155
    edited August 2011

    Thanks for the replys.   I will check out the 2 forums that were recommended.   

  • dsj
    dsj Member Posts: 277
    edited August 2011

    If your tumor is positive for estrogen receptor, tamoxifen will reduce your risk of recurrence by about half--i.e., 50%. That percentage is known because of long- term large research studies. Not to say holistic might not help too, but there's no comparable research (i.e. Large clinical trials). Not everyonr can take tamoxifen, but you might ask you oncologist what your own personal recurrence risk is, and then decide if it is worth it to you to take tamoxifen. I was worried too about tamoxifen side effects. After some intense hot flashes the first few months, everything has calmed down, and I am glad to have the extra protection.

  • xtine
    xtine Member Posts: 131
    edited August 2011

    Most of the alternatives I've heard of work to reduce the amount of estrogen in your body. I'm guessing if you're pre-menopausal, it's going to be pretty hard to reduce estrogen naturally to a level that will have any effect. Tamoxifen works differently - it binds to estrogen receptors (as opposed to reducing estrogen). I'm not sure if there are any alternatives that have the same type of effect.

    You might question the actual benefit of Tamoxifen. While it reduces recurrence by 50%, if your chance of recurrence is only 4%, say, then that's a 2% reduction overall, and may not be worth it to you. Your oncologist can help you understand the risks.

    Personally, I am on Tamoxifen (I am under 40 and my risk of recurrence or new cancer seemed high enough to me to make it worth it). I really have had minimal side effects, as have many women. The horror stories tend to get more attention, but for many many women this is a good choice. Also, as my oncologist pointed out, you can always stop if it doesn't work out for you.

  • echosg
    echosg Member Posts: 12
    edited August 2011

    Exactly.  It's important to understand the difference between your relative risk and your absolute risk.  For pure DCIS, my personal risk of recurrance was around 3%.  So, a 50% reduction is 1.5%.  1.5% wasn't worth the side-effects and potential uterine cancer - which is one of the cancers my mother died from.

  • ej01
    ej01 Member Posts: 155
    edited August 2011

    So, who gives you your Personal risk of reoccurance?   Does the Radiology oncologist do that or will I need to go to a different oncology type for that?    I am assuming i will have to wait until after my I get the pathology report from the lumpectomy to get this figured out, right?

  • xtine
    xtine Member Posts: 131
    edited August 2011

    ej - I would talk to your medical oncologist (you should have one if you are considering tamoxifen). And I think the final pathology will help. Though my oncologist was ready to start to discuss post-surgery options pre-surgery based on initial pathology and my genetics test results (BRCA-).

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