Recent start on Adriamycin and Cytoxan for chemo

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I had my first dose on monday July 25. I had premeds, and was ok for 2 days. Day 3 was quite hard with the fatigue and turedness. I couldn't even cry, not enough energy!.I made it through, today was better than yesterday. Is there anyone else out there that just started treatment?

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  • tlundy
    tlundy Member Posts: 142
    edited July 2011

    Hi Jenn,

    I haven't just started, but I had four dose dense treatments of A/C starting in December 2010.  It isn't easy, and everyone responds differently.  While it is challenging, you will make it through it.  It is very important to drink plenty of fluids and rest as much as you feel you need to.  It will probably seem to you that just as soon as you are feeling like yourself again it's time for another treatment, but try not to let it get you down.  You will determine what your cycle is like and be able to anticipate when your roughest days will be so you can plan around that. Are you doing Taxol after the A/C?

    Hugs to you and positive thoughts going your way!  Keep us posted on how it's going - hang in there and we are here for you!

    Tara

  • jbagley
    jbagley Member Posts: 102
    edited July 2011

    Today is day 7 since my infusion. I feel ok, but still quite tired. I could take a nap! My appetite has only picked up a little. Nothing tastes right, everything leaves a funny taste in my mouth. I also have a funny smell in my nose, no one else can smell what I smell. I used to smoke but quit about 4 yrs ago. I have this awful cigarette smell stuck in my nose and it makes me sick to my stomach. I hope it is just the chemo playing tricks with my senses.



    It is getting better. My hair hasn't really started falling out yet. Just a few strands here and there. No clumps yet. We will see. One other issue that I have found is a sore throat. No white patches though.

    Jennifer

  • reesie
    reesie Member Posts: 2,078
    edited July 2011

    Jenn I had AC as my first chemo and felt flu sick yucky around days 5-8 until the neulasta shot kicked in and ny wbc went back up.



    Look on the chemo forum for the July 2011 chemo group (or since it's practilly her already the August 2011 group). You'll find others going through the same as you at the same time. It can really help.

  • tlundy
    tlundy Member Posts: 142
    edited July 2011

    Jenn, chemo can do strange things to your senses.  If you are having a metallic taste in your mouth, try eating with plastic utensils - it may help.  With regard to your hair, most people lose the bulk of it around the 14th day.  When mine started coming out to the point that it was becoming an irritant I had my head shaved.  It made me feel more in control of the situation. There is a thread called "Hair, Hair, Hair" that you may find helpful.  I agree with Reesie that it does help to communicate with others going through the process at the same time as you are.  However, there are also tons of women that have gone through the experience who are here to share information, tips, and advice that can be invaluable so I encourage you to continue to tap into the "veterans" wisdom as well.  So glad to hear you're feeling a bit better.  Stay strong - PEACE!

    Tara

  • jbagley
    jbagley Member Posts: 102
    edited August 2011

    Thank you for all the support. I am feeling better today. Today is day 7. One day, one treatment at a time.



    Thank you.

    Jenn

  • 46MD
    46MD Member Posts: 25
    edited August 2011

    Hi all. I'll be starting AC dense dose next week sometime. Not looking forward to it, but the sooner its over, the better. Hopefully I'll be able to work some. Also, I thought you felt crappier right after a dose, but someone mentioned it didn't hit till day 7? Any more info on that? Or does it just come down to individual experience? thanks for sharing everyone :)

  • jbagley
    jbagley Member Posts: 102
    edited August 2011

    46MD, hi I'm jenn, I just had my first dose last monday. I was ok that day and day 2, day 3, 4,5 caused me fatigue. Very tired, rest as much as possible, if you get a spurt of energy, don't do anything about it. I did on day 3 in the am, I vacuumed, I shouldn't have, I was fatigued the rest of the day. Rest. Drink lots of fluids. I found gingerale and juice went down the best with ice. I also pretty much ate a whole watermelon myself. My kids only got a little bit. The water in the melon helps!



    Good luck with your first treatment, just listen to your body. You will hear it. Meditation and reiki are also good. I have had several reiki tx since my dx. (I am a Nurse practitioner, you're an MD?).. sometimes too much information is worse. Good luck. Jenn



    1 down and 7 to go. Adriamycin/cytoxan X4 rounds, taxol X4 rounds.

  • 46MD
    46MD Member Posts: 25
    edited August 2011

    Hi Jenn. MD stands for Maryland :)

    Thanks for the tips. I can't believe the fatigue! I was hoping to try to go to work some. Maybe I need to plan different. Hopefully its temporary. A very good friend of mine is a Reiki practitioner, so I will put her to work!

  • calamtykel
    calamtykel Member Posts: 1,187
    edited August 2011

    Aw- hugs to you guys!  I started chemo in August of last year.  My first AC was like a ton of bricks hit me, but it was my own fault - I didn't take my anti-nausea meds.  They didn't tell me I had to - I thought getting them in the IV was enough.  I was extremely sick that night!  I learned that lesson the hard way.  After the first one, I didn't throw up at all because I would take the ativan and compazine religiously for 24 hours after my chemo.  That would be my advice - is to be careful to take those meds.  :)

    I know the fatigue is so hard! :(  I remember after one of my treatments my  mom came here on day 2 or 3 and the whole day was a blur.  She took care of my four kids and I just slept on and off all day.  Get up, go to the bathroom and get wiped out from just that.  Go to the kitchen for a drink of water and get wiped out from that.  When I tried to rest, I would just doze in and out of a haze and it wasn't restful.  Chemo is heavy duty stuff!  But it WILL go away; you will feel good again.  I have been running 3-4 miles a night six nights a week.  It does get better even when you feel like it never ever will! :)

  • 46MD
    46MD Member Posts: 25
    edited August 2011

    calamtykel- thanks for the words of encouragement.

  • jbagley
    jbagley Member Posts: 102
    edited August 2011

    46MD, thank you for the clarification of MD. Sorry.



    Calamtykel....I had the same fatigue. It even hurt and caused more fatigue to cry! It's nothing I have ever felt before! I am doing a lot better today, today is day 9 (tuesday) and I start all over again on monday. The only lasting issue I have had is a sore throat. No white patches but sore, heartburn, worse than when I was pregnant! Bad heartburn. Pepcid usually helps.



    Talk to you soon.

    jenn

  • edyem
    edyem Member Posts: 38
    edited August 2011

    Hi Jenn,



    I'm six days out from my first dose and each day has been different. Days 2-5 I felt as if I had a hangover without benefit of the party to bring one on. I had several hot flashes yesterday that scared me a bit. (It's in the triple digits here in Texas, but this happened indoors.) Now I have back pain and a sore throat which could be due to the Neulasta shot I received day 2. I find I do best if I stay hydrated (ginger ale and cranberry icy drinks have been most appealing to me) and just eat a little bit when I feel hungry.



    Good luck to you. I know we can do it and it's great to see positive like calamtykel's.

  • brca1babe
    brca1babe Member Posts: 75
    edited August 2011

    I totally agree that AC feels like a really bad hangover - queasy, weak, tired, lightheaded and foggy headed but no funny memories of a party.

    luckily this "hangover" last only about 4 days for me but I really feel horrible during that time.  sleeping and pacing myself helps.  Then I feel a bit better until my counts drop further (despite neulasta) and around day 9 I am again tired and foggy, I think that's when I feel the anemia and then it gets better the 2-3 days before treatment I feel pretty good...  and then back for more!

    only one more treatment to go...

  • Sassa
    Sassa Member Posts: 1,588
    edited August 2011

    I had 4AC (one every three weeks) from 12/06 - 2/07.

    I found the effects to be cumulative.  The first one, I was OK after 3 days.  By the last one, I was dragging my rear end for two weeks afterwards.

    I also had increasing problems with nausea after each dose (spent the night after dose two heaving all night) so I was given increasingly stronger doses of anti-emetics.

    The AC  also killed my appetite (as did the herceptin) and I had to force myself to eat. Since I wasn't hungry, I ate nutritious meals, but am one of those  people that lost weight (30 lbs) while on chemo and herceptin.

    Edyem, the hot flashes are from the steroids you are given in the premedication.  Although I was going through menopause while on chemo, I never suffered from hot flashes.  The steroid let me know what I was (not) missing.

  • pearlone
    pearlone Member Posts: 1
    edited August 2011

    I finished chemo (A/C and Taxol) in December last year. Just want all you gals to know that the treatment will pass much quicker than you would imagine.

    Liquid, liquid, liquid is the best thing you can do for yourself. Ginger ale helped me alot. If it's hard to drink anything, just take small sips as often as you can.

    A/C was much harder than Taxol. My third treatment was the hardest (I think I got dehydrated)and my wonderful Onc suggested I have my final one done on a very slow drip (48 hrs) in the hospital. I took her advice and am SO glad I did. Two days in the hospital was definitely better than 4-5 days in the fetal position!

    This will all be behind you sooner than you think. Hang in there!!!

  • LindaF
    LindaF Member Posts: 29
    edited August 2011

    HI

    I have just finished round 2 of DD AC.  After my first round on 5 JUL, I experienced the return of the severe, constant chest/incisional pain that was just as if I had come out of the original anesthesia.from the MRM back on 26 MAY 2011.  (I had been feeling pretty good, could move my arm fairly well.)   After 3 days, they discovered I had a PE, and I kind of figured that was the end of this return of pain.  But I had the exact same unbelieveable return of the chest pain again on day 4 post chemo with this second round (my original second round was delayed due to elevated LFTs), which lasted now 72 hours and is finally easing back to where I can actually think about something else.   I have to say, knowing or suspecting that I am going to find myself back in this vicious chest/incisional pain for 3 days or more after each round is very discouraging.  I am scheming of ways to delay the next chemo until I can forget this past dose.

    Anyone else experience this incisional pain return???

    Thanks, Linda

    Diagnosis:left  MRM 26 MAY with expander placement, 6/11 +nodes, 7 cm mass ILC, mets to lung and supraclavicular, HERs2-, est/prog +, not found on any mammo or US, I noted a slight dimpling of my nipple, asked for a biopsy..were THEY all surprised?...   Oh, wound infection, PE after 1st round DD AC, elevated LFTs, neutropenia, now parallytic illieus post chemo.

     

  • edyem
    edyem Member Posts: 38
    edited August 2011

    Thank you, Sassa.  I read about hot flashes as a side effect, but didn't know that they were a direct cause of the steroids.  My ME has me take steroids on day 2, 3, and 4 as well.  I've felt MUCH better for almost a week now.  My next infusion is the 18th, so I'm already dreading it.  I'm planning to "pre-hydrate" to try and lessen the hangover effect this time.  

  • Fearless_One
    Fearless_One Member Posts: 3,300
    edited August 2011

    Just wanted to say that I had 6 rounds of DD  A/C and did quite well.  Don't get me wrong, it wasn't a picnic, but I was expecting far worse.      

  • jbagley
    jbagley Member Posts: 102
    edited August 2011

    I just had A/C treatment #2. Day 4, is worse this time. I got some different nausea med, phenergan, works well with me. Taste buds are gone for another 5 days. Again feeling weak, shakey, 'hungover' like. Foggy, decreased energy to talk.



    Drink, drink, drink......... eating fruit mostly. Watermellon, grapes. Gingerale.



    Going to bed now. Start another new dayh tomorrow, hopefully with a bit more energy.



    Jen

  • pickle
    pickle Member Posts: 1,409
    edited August 2011

    I had AC and each time day 4,5,6 made me feel like I was hit by a truck and then I would rebound. Drink lots, rest lots . I rinsed my mouth numerous times a day with club soda ( recommended by the cancer center) and didn't get any mouth sores. My taste buds were way off and I ate alot of mashed potatoes, oatmeal...bland stuff which helped keep my stomach settled. Good luck and this will be behind you before you know it.

    Hugs

    Beth

  • D4Hope
    D4Hope Member Posts: 352
    edited August 2011

    I went through four rounds of these chemos two years ago. The nausea meds helped but I did get alot of fatigue. I made sure to drink lot's of fluids and napped as often as I could. I wish you luck, you will get through this.

  • jbagley
    jbagley Member Posts: 102
    edited August 2011

    Thank you all.



    Watermellon is my friend! Haha. Can't get enough of it and really cold juice,



    Jenn

  • theatercat
    theatercat Member Posts: 58
    edited August 2011

    I will start treatment Aug.26 with same meds. My concern as I will post it here, for I have forgotten how to start anew topic. I have MRSA since surgery in June. I had all my teeth extracted 4 days ago because of  chronic infections. My plight is I am to have a port put in on tuesday Aug. 16th. I am on rifapin and doxycycline for mrsa. I see my breast surgeon on monday to check wound. I would feel so much better to push back port until my mouth is healed  and MRSA is under control. My veins are not good. I will get treatment once every 3 weeks. I say they can use my veins for first treatment and get the port in Sept. Any feedback will be so welcomed. Thansk AMY

  • jbagley
    jbagley Member Posts: 102
    edited August 2011

    Dear Theatercat, you should get the mrsa under control, but you shouldn't be getting these high chemo doses through your. 'Bad' veins. Adriamycin is very caustic to the skin. If your IV infiltrates, it would not be good. Speak with your oncologist. They are the cancer spcialist. They will have an answer for you.



    I am just recovering from my #2 A/C tx. It hit me a day later this time. Pretty bad on day 4 and 5, today is day 6 and I actually woke up and wanted to go outside. My mom was here for the weekend to help with my 3 yr old, I couldn't have done it without her. My husband had to work, no daycare on weekend. My mom loves to come visit the grandkids.

    jennifer, another one done!

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