Questions about Pathology report
What does the following mean?
Tumor formation score: 3 of 3
Nuclear grade score: 2 of 3
Mitotic score: 1 of 3
Tumor grade 11/111 (score 6/9)
Longest confluent tumor focus measure 0.9 cm
angioloyphatic invatsion: not identified
Microcalcification:: Not identifed
Estrogen receptor, progesterone receptor, and HER-2/neu studies: pending, to be reported by addendum then says: Estrogen receptor: Positive. and says: Nuclear staing seen in 100% of invasive tumor cells with strong avg. intensity. Internal control cells are not present.
Progesterone receptor: Positive Nuclear staing seen in 25% of invasive cells with stong avg. intensit. Internal control cells are not present.
The fixative is 10% NBF
I probably gave u too much, but I don't know what to list.
Comments
-
Hi vickilf,
Our tumors are graded to see how aggressive thery are from 1-3, 3 being the most aggressive. They take and score formation, nuclear grade and mitotic scores and evaluate each of them from 1-3, add them up, that is your total score (6 out of 9) then divide by 3 to grade (2 out of 3). So you don't have the most aggressive form, and it's not the most laid back, you are a grade 2. Your longest measurement was .09, just under 1 cm, and they did not see any angioloyphatic invasion or calcifications, which is a positive thing.
Your ER/PR and Her2 will be pending, they are stained for a certain period of time, and then the results are given in an addendum, usually in about 10 days, but they did stain them and the initial looks like you are ER+ PR+ which means your tumor was driven by both estrogen and progesterone.
All of that combined means you now know the signature of your tumor.
I hope this helps a bit!
((Hugs))
-
Oh thank you so much for your explanation.
-
ER/PR+ is a good thing because it allows you to be treated with Tamoxifen. I am also Grade 2 and ER/PR+. Did they tell you the stage? I would think Stage 1? If that's the case you caught it early and that is also a good thing! I am Stage 1 too.
-
They did not tell me my stage yet, Doctor said more info after lumpectomy
mdg what kind of treatment did u have?
Categories
- All Categories
- 679 Advocacy and Fund-Raising
- 289 Advocacy
- 68 I've Donated to Breastcancer.org in honor of....
- Test
- 322 Walks, Runs and Fundraising Events for Breastcancer.org
- 5.6K Community Connections
- 282 Middle Age 40-60(ish) Years Old With Breast Cancer
- 53 Australians and New Zealanders Affected by Breast Cancer
- 208 Black Women or Men With Breast Cancer
- 684 Canadians Affected by Breast Cancer
- 1.5K Caring for Someone with Breast cancer
- 455 Caring for Someone with Stage IV or Mets
- 260 High Risk of Recurrence or Second Breast Cancer
- 22 International, Non-English Speakers With Breast Cancer
- 16 Latinas/Hispanics With Breast Cancer
- 189 LGBTQA+ With Breast Cancer
- 152 May Their Memory Live On
- 85 Member Matchup & Virtual Support Meetups
- 375 Members by Location
- 291 Older Than 60 Years Old With Breast Cancer
- 177 Singles With Breast Cancer
- 869 Young With Breast Cancer
- 50.4K Connecting With Others Who Have a Similar Diagnosis
- 204 Breast Cancer with Another Diagnosis or Comorbidity
- 4K DCIS (Ductal Carcinoma In Situ)
- 79 DCIS plus HER2-positive Microinvasion
- 529 Genetic Testing
- 2.2K HER2+ (Positive) Breast Cancer
- 1.5K IBC (Inflammatory Breast Cancer)
- 3.4K IDC (Invasive Ductal Carcinoma)
- 1.5K ILC (Invasive Lobular Carcinoma)
- 999 Just Diagnosed With a Recurrence or Metastasis
- 652 LCIS (Lobular Carcinoma In Situ)
- 193 Less Common Types of Breast Cancer
- 252 Male Breast Cancer
- 86 Mixed Type Breast Cancer
- 3.1K Not Diagnosed With a Recurrence or Metastases but Concerned
- 189 Palliative Therapy/Hospice Care
- 488 Second or Third Breast Cancer
- 1.2K Stage I Breast Cancer
- 313 Stage II Breast Cancer
- 3.8K Stage III Breast Cancer
- 2.5K Triple-Negative Breast Cancer
- 13.1K Day-to-Day Matters
- 132 All things COVID-19 or coronavirus
- 87 BCO Free-Cycle: Give or Trade Items Related to Breast Cancer
- 5.9K Clinical Trials, Research News, Podcasts, and Study Results
- 86 Coping with Holidays, Special Days and Anniversaries
- 828 Employment, Insurance, and Other Financial Issues
- 101 Family and Family Planning Matters
- Family Issues for Those Who Have Breast Cancer
- 26 Furry friends
- 1.8K Humor and Games
- 1.6K Mental Health: Because Cancer Doesn't Just Affect Your Breasts
- 706 Recipe Swap for Healthy Living
- 704 Recommend Your Resources
- 171 Sex & Relationship Matters
- 9 The Political Corner
- 874 Working on Your Fitness
- 4.5K Moving On & Finding Inspiration After Breast Cancer
- 394 Bonded by Breast Cancer
- 3.1K Life After Breast Cancer
- 806 Prayers and Spiritual Support
- 285 Who or What Inspires You?
- 28.7K Not Diagnosed But Concerned
- 1K Benign Breast Conditions
- 2.3K High Risk for Breast Cancer
- 18K Not Diagnosed But Worried
- 7.4K Waiting for Test Results
- 603 Site News and Announcements
- 560 Comments, Suggestions, Feature Requests
- 39 Mod Announcements, Breastcancer.org News, Blog Entries, Podcasts
- 4 Survey, Interview and Participant Requests: Need your Help!
- 61.9K Tests, Treatments & Side Effects
- 586 Alternative Medicine
- 255 Bone Health and Bone Loss
- 11.4K Breast Reconstruction
- 7.9K Chemotherapy - Before, During, and After
- 2.7K Complementary and Holistic Medicine and Treatment
- 775 Diagnosed and Waiting for Test Results
- 7.8K Hormonal Therapy - Before, During, and After
- 50 Immunotherapy - Before, During, and After
- 7.4K Just Diagnosed
- 1.4K Living Without Reconstruction After a Mastectomy
- 5.2K Lymphedema
- 3.6K Managing Side Effects of Breast Cancer and Its Treatment
- 591 Pain
- 3.9K Radiation Therapy - Before, During, and After
- 8.4K Surgery - Before, During, and After
- 109 Welcome to Breastcancer.org
- 98 Acknowledging and honoring our Community
- 11 Info & Resources for New Patients & Members From the Team