TC vs. ddTC
I'm looking for some advice as I make my chemo decision. MO is recommending TC x 4 every three weeks but there is a new research opportunity starting in the next few weeks looking at dense dose TC with Neulasta every two weeks. He says I would be a perfect candidate for this trial. I am concered that the side effects of the dd TC will be too much and would love to hear what others have experienced.
Comments
-
It's hard to say because you don't know how your body can handle it. I did ddAC every 2 weeks X4 and the went to Taxol X8. I was suppose to do dd taxol but I started having neuropathy so they went with the single dose every week. For my last 3 they stitched to Taxotere which was far worse than and of the others.
Which T are they planning on doing?
All you can do is try dd & if you don't tolerate it well then you can go to the single dose. NJ
-
Taxotere and cyclophosphamide.
-
kl22: Somewhere on here, or maybe on the chemo board, there is a thread about TC, and you may want to post there to find some women who did dose dense.
It is very hard to predict how your body will react to any chemo. I elected to do dose dense AC and, despite some warning from my onc that it would be a tough slog, I found it quite manageable. I think it helped that I was in reasonably good shape to start, and kept exercising throughout.
Is it possible you could start with the dd schedule and have a fall-back plan if the SEs are too much?
-
kll22 ~ Having done TCx4, one thing I would research if I was you before agreeing to either regimen is the permanent hair loss a very few BCO members have reported. There's a thread on it here. Thankfully, it appears to be a very rare SE. But I'd want to know if any of those who are dealing with it now did DD, or if there's any suspected link to an increased possibility with DD, or if DD might even help ensure that doesn't happen.
The only major issue I had with TC was extreme muscle weakness, and, in retrospect, I wonder if that might have been lessened if I'd gotten through it quicker. It certainly would have been nice to get it over with faster.
Good luck, whichever you decide to do ~ Deanna
-
I've been doing DD AC (every 2 weeks) for 4 treatments, although they had to reduce the chemo dosage because of a zero white blood count after the first treatment. Supposedly it's because I''d had chemo before. The every-two-week schedule itself has been totally doable for me. I'm about to start now on DD Taxol (every 2 weeks) but again we'll have to see how that goes. They might have to put me on 12 weekly treatments if the blood counts go south again. But if I were you, I'd go ahead and try the DD schedule. If it's too much, your oncologist will move you back to every 3 weeks so you really won't have lost anything. Good luck.
-
I did dd AC, got finished 5 weeks ago. It was doable. Then I started dose dense Taxol with weekly Herceptin. I ended up having an allergic reaction to Taxol and having to switch to Taxotere. Having 3 of those every 3 weeks. Had the first one 6 days ago. So far, it is okay, although I do feel weaker than I did on AC. I think I'm glad I'm not doing dd. But then I just came out of the AC and lung problems because of the allergic reaction. Maybe that has something to do with it. Good luck with which ever you choose.
Categories
- All Categories
- 679 Advocacy and Fund-Raising
- 289 Advocacy
- 68 I've Donated to Breastcancer.org in honor of....
- Test
- 322 Walks, Runs and Fundraising Events for Breastcancer.org
- 5.6K Community Connections
- 282 Middle Age 40-60(ish) Years Old With Breast Cancer
- 53 Australians and New Zealanders Affected by Breast Cancer
- 208 Black Women or Men With Breast Cancer
- 684 Canadians Affected by Breast Cancer
- 1.5K Caring for Someone with Breast cancer
- 455 Caring for Someone with Stage IV or Mets
- 260 High Risk of Recurrence or Second Breast Cancer
- 22 International, Non-English Speakers With Breast Cancer
- 16 Latinas/Hispanics With Breast Cancer
- 189 LGBTQA+ With Breast Cancer
- 152 May Their Memory Live On
- 85 Member Matchup & Virtual Support Meetups
- 375 Members by Location
- 291 Older Than 60 Years Old With Breast Cancer
- 177 Singles With Breast Cancer
- 869 Young With Breast Cancer
- 50.4K Connecting With Others Who Have a Similar Diagnosis
- 204 Breast Cancer with Another Diagnosis or Comorbidity
- 4K DCIS (Ductal Carcinoma In Situ)
- 79 DCIS plus HER2-positive Microinvasion
- 529 Genetic Testing
- 2.2K HER2+ (Positive) Breast Cancer
- 1.5K IBC (Inflammatory Breast Cancer)
- 3.4K IDC (Invasive Ductal Carcinoma)
- 1.5K ILC (Invasive Lobular Carcinoma)
- 999 Just Diagnosed With a Recurrence or Metastasis
- 652 LCIS (Lobular Carcinoma In Situ)
- 193 Less Common Types of Breast Cancer
- 252 Male Breast Cancer
- 86 Mixed Type Breast Cancer
- 3.1K Not Diagnosed With a Recurrence or Metastases but Concerned
- 189 Palliative Therapy/Hospice Care
- 488 Second or Third Breast Cancer
- 1.2K Stage I Breast Cancer
- 313 Stage II Breast Cancer
- 3.8K Stage III Breast Cancer
- 2.5K Triple-Negative Breast Cancer
- 13.1K Day-to-Day Matters
- 132 All things COVID-19 or coronavirus
- 87 BCO Free-Cycle: Give or Trade Items Related to Breast Cancer
- 5.9K Clinical Trials, Research News, Podcasts, and Study Results
- 86 Coping with Holidays, Special Days and Anniversaries
- 828 Employment, Insurance, and Other Financial Issues
- 101 Family and Family Planning Matters
- Family Issues for Those Who Have Breast Cancer
- 26 Furry friends
- 1.8K Humor and Games
- 1.6K Mental Health: Because Cancer Doesn't Just Affect Your Breasts
- 706 Recipe Swap for Healthy Living
- 704 Recommend Your Resources
- 171 Sex & Relationship Matters
- 9 The Political Corner
- 874 Working on Your Fitness
- 4.5K Moving On & Finding Inspiration After Breast Cancer
- 394 Bonded by Breast Cancer
- 3.1K Life After Breast Cancer
- 806 Prayers and Spiritual Support
- 285 Who or What Inspires You?
- 28.7K Not Diagnosed But Concerned
- 1K Benign Breast Conditions
- 2.3K High Risk for Breast Cancer
- 18K Not Diagnosed But Worried
- 7.4K Waiting for Test Results
- 603 Site News and Announcements
- 560 Comments, Suggestions, Feature Requests
- 39 Mod Announcements, Breastcancer.org News, Blog Entries, Podcasts
- 4 Survey, Interview and Participant Requests: Need your Help!
- 61.9K Tests, Treatments & Side Effects
- 586 Alternative Medicine
- 255 Bone Health and Bone Loss
- 11.4K Breast Reconstruction
- 7.9K Chemotherapy - Before, During, and After
- 2.7K Complementary and Holistic Medicine and Treatment
- 775 Diagnosed and Waiting for Test Results
- 7.8K Hormonal Therapy - Before, During, and After
- 50 Immunotherapy - Before, During, and After
- 7.4K Just Diagnosed
- 1.4K Living Without Reconstruction After a Mastectomy
- 5.2K Lymphedema
- 3.6K Managing Side Effects of Breast Cancer and Its Treatment
- 591 Pain
- 3.9K Radiation Therapy - Before, During, and After
- 8.4K Surgery - Before, During, and After
- 109 Welcome to Breastcancer.org
- 98 Acknowledging and honoring our Community
- 11 Info & Resources for New Patients & Members From the Team