HRT causing breast cancer
Comments
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Just curious how many of you woman who have breast cancer, had been on HRT for menopausal symptoms and for how long?? Also, if you are already well into menopause, do you still need to take Tamo if you have breast cancer??
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It's not that there's no need for tamox for someone post-meno, it's that AIs are usually considered more effective but are only for post-meno women.
The issue of tamox or AI not being needed if you have no breast tissue is only for those who had DCIS. For a woman who had an invasive cancer, tamox or an AI is used in case any cancer cells are still alive in another part of your body and could cause mets.
As far as HRT - I can give you my mother's example. She had osteoporosis and her doc put her on HRT when she was in her early 70s (about 20 years post-meno). Within 4-5 years she had bc (no hx of bc in her family; my father's family is full of it). Her onc is sure it was the HRT. I don't know why her doc didn't give her a bisphosphonate since, though new, they were being used and were not in the trial stage. I didn't use HRT.
Leah
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my mom went thru menopause between 47 and 51--took HRT sometime during those 4 years for menopausal symptoms; developed ILC at age 58. She then had lumpectomy, radiation and 5 years of tamoxifen. Did the HRT contribute to her bc? Don't know for sure, but it does make you wonder. Doctors told my sisters and I to never take it due to our mom's bc.
Anne
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I went into "early" menopause at age 47 (8 years ago). I had a number of discussions with my GYN. Research at the time indicated that it would be safe to do a short course of HRT, until I reached a more "normal" menopausal age (to protect my bones and my heart - those were the research findings at the time). How much did it contribute? I guess we'll never know for certain.
I have a history of severe endometriosis with two major abdominal surgeries and two courses of Danazol in my 30s to throw me into temporary menopause in an effort to shrink endometrial tissue. I also took birth control pills for many years to help with the symptoms of endometriosis. Also, I have never been pregnant. So, I have a history of lots of hormonal "tinkering" over the years.
I also had extremely dense breast tissue, which I recently read is not just a problem for diagnosing BC, it is actually now considered a strong risk factor.
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Hi, JPRacket45;
I was on hormone cream for about 5 years for menopause symptoms. I started menopause around age 50-51, and I felt great using it! Five years later (2010) I was diagnosed with IDC. The BS said nothing I did caused it. I was the right age and gender to get the most commonly diagnosed type of breast cancer. I am osteopenic, so the ONC prescribed Tamoxifen for me, because it has been shown to actually help bones, rather than putting me on a aromatase inhibitor, since they increase bone loss. After 7.5 months of Tamoxifen, I have stopped taking it, because of SE's and QOL issues. The Tamoxifen is give to any woman who's cancer is estrogen receptor positive. The aromitase inhibitors are only given to women who have gone thru menopause and hormone receptor positive.
Hope that helps
Suzanne
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JP, I was on Prempro for about 15 years, and I strongly believe it was a key factor in my developing bc. Having gotten off HRT cold turkey when dx'd, and being well into menopause factored strongly into my decision not to take an A/I or Tamox after having a bad reaction to Femara, which might have been partly caused by the double-whammy I gave my body when I tried it. I am using a natural estrogen modulator, as well as some diet modifications (i.e. very low protein & dairy), which is about all the futher estrogen deprivation my body can tolerate. Deanna
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I was on HRT for about 10 years. I had severe hot flashes when I tried to go off it, so kept going on reduced dosages, that took the hot flashes down to manageable levels. I was tapering off when I was diagnosed.
Did it cause the breast cancer? I don't know. It definitely fed it (100% ER+ and PR+)
I'm on Femara now, and the hot flashes are back, but manageable.
Hope this helps.
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I had been taking it for 4 years. My cancer was highly ER receptive - an indicator that it may have been caused by HRT. Add in to that many many years on the pill - 5 times the strength of HRT!!!
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I was on HRT for two years before being diagnosed. They told me that the HRT didn't cause my breast cancer, which probably had been there for years, but certainly fueled it. My tumor had actually been palpable for years but they kept me on the HRT because my mammograms came back clear. It wasn't until I insisted on an ultrasound that my cancer was diagnosed.
I'm on anastrozole now.
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Yes, mammograms repeatedly missed mine, too, which was also palpable. I found it myself with a self-exam. The MRI and ultrasound did show it, though. I had had about a gazillion mammogram shots that did show calcifications but they said it was fine when they checked it after 6 months again. I found it myself a couple of months later, and it was a very slow growing type that definitely was there while I was getting mammograms.
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9 years of just enough HRT(post TAH-BSO, so surgical menopause at 45 due to numerous symptomatic uterine fibroids) to keep the 20+ hot flashes a day under control, and be able to sleep a little at night. I am strongly ER+ but my smallish tumor was caught relatively early, not visible at all on mammo which I have had annually for at least 20 years, but palpable and visible on US. Quit HRT cold-turkey day of dx.
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my nana passed in april from secondary breast cancer, she had been on hrt from the age of 24 (she had a histrectomy) she was 66 when she passed. She thinks HRT had something to do with it. My mum has just refused HRT because of my nan x
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Because of a strong family history my doctor told me to never take HRT, but they say birth control pills are ok for my daughter to take? That's what I worry about - her taking the pill for a long period of time....
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Breast Cancer is usually Generic.
Cancer can be caused by Genetics,exposture to enivornmental toxins,or even from certain viruses or possibly even bacteria.
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