What does triple negative mean?
My best friend B was diagnosed in October of last year. Her "mass" was measured @ 7mm X 6mm. After 6 rounds of Taxotere she had a double mastectomy and the surgeon said her lymph nodes (she took 4) had scar tissue as did her breast. The pathology report indicated that the mass shrunk to the size of a pin prick. We are somewhat clueless about what to expect from here on out. I know that sounds silly at this point, but we (our families) can't seem to wrap our brains around what triple negative cancer means...BTW, she is 36.
Comments
-
-Also, her doc wouldn't "stage" her. I'm not sure why, but he tried to get us off of that subject. Is that normal?
-
It refers to whether the tumor has the receptors for estrogen, progesterone and HER2. Each tumor is unique and the information will be in the pathology report. The most successful treatments target these receptors, sometimes with hormonals or Herceptin, but they are not indicated for triple negatives. TNBC can also be more aggressive and tends to recur more quickly. My recurrence came just two years from my initial diagnosis (at which time I was 49); not only was the cancer back in the form of a new tumor, but it had metastasized.
The lack of receptors can make the cancer more difficult to treat. I am a triple negative and am told that chemotherapy is really my only option. That being said, the disease also responds well to chemotherapy in many cases.
My first oncologist did not seem to consider my case special in any way and delivered what he later defended as the "standard of care" for my diagnosis. I think your friend should educate herself about what being triple negative means, there are many sources of information, and don't hesitate to get a second or even a third opinion. If I had it to do over I would have found an oncologist to treat me as aggressively as possible. It might not have made a difference, or it might have changed everything. I will never know, but I am now in a fight for my life.
I wish her well, she may find this forum a great source of information, camaraderie and comfort. I know that I do.
-
Thank you MJsMoM! Her surgeon said that the oncologist did a great job and was very aggressive. She is worried it will come back after all of this hard work. What about radiation?
-
The only tools currently available for triple negative breast cancer are chemotherapy and radiation,but they work very well. Usually, we get both to the extent they are safe for us. The oncologist needs to decide if further chemo is warranted, and if radiation should be done.
-
MJsMom - I feel that my mom's oncologist is also considering it "standard case". I just feel like it isn't. Should I be concerned that my oncologist is only giving my mom 4 treatments of chemo?
-
I had inflammatory breast cancer but it wasn't until another theacher at my school got TripleNeg BC did I began to understand what that meant. 1. Estrogren resceptors negative, 2.Progesterogen receptors negative 3. Heur2 reseptors negative; thus Triple negative. Through this event I learned I had both Inflammatory & triple negative bc. Both aggressive & rare. It does respond well to treatment anf you have to take any hormons after treatment is over. But it also has a hgher rarte of reoccurrance. I am now out 3 1/2 years. ;
-
Norma June~ I know this is a small world, but you so look like a friend of mine, Karen. She passed away this year. Seeing your picture made me smile.
Categories
- All Categories
- 679 Advocacy and Fund-Raising
- 289 Advocacy
- 68 I've Donated to Breastcancer.org in honor of....
- Test
- 322 Walks, Runs and Fundraising Events for Breastcancer.org
- 5.6K Community Connections
- 282 Middle Age 40-60(ish) Years Old With Breast Cancer
- 53 Australians and New Zealanders Affected by Breast Cancer
- 208 Black Women or Men With Breast Cancer
- 684 Canadians Affected by Breast Cancer
- 1.5K Caring for Someone with Breast cancer
- 455 Caring for Someone with Stage IV or Mets
- 260 High Risk of Recurrence or Second Breast Cancer
- 22 International, Non-English Speakers With Breast Cancer
- 16 Latinas/Hispanics With Breast Cancer
- 189 LGBTQA+ With Breast Cancer
- 152 May Their Memory Live On
- 85 Member Matchup & Virtual Support Meetups
- 375 Members by Location
- 291 Older Than 60 Years Old With Breast Cancer
- 177 Singles With Breast Cancer
- 869 Young With Breast Cancer
- 50.4K Connecting With Others Who Have a Similar Diagnosis
- 204 Breast Cancer with Another Diagnosis or Comorbidity
- 4K DCIS (Ductal Carcinoma In Situ)
- 79 DCIS plus HER2-positive Microinvasion
- 529 Genetic Testing
- 2.2K HER2+ (Positive) Breast Cancer
- 1.5K IBC (Inflammatory Breast Cancer)
- 3.4K IDC (Invasive Ductal Carcinoma)
- 1.5K ILC (Invasive Lobular Carcinoma)
- 999 Just Diagnosed With a Recurrence or Metastasis
- 652 LCIS (Lobular Carcinoma In Situ)
- 193 Less Common Types of Breast Cancer
- 252 Male Breast Cancer
- 86 Mixed Type Breast Cancer
- 3.1K Not Diagnosed With a Recurrence or Metastases but Concerned
- 189 Palliative Therapy/Hospice Care
- 488 Second or Third Breast Cancer
- 1.2K Stage I Breast Cancer
- 313 Stage II Breast Cancer
- 3.8K Stage III Breast Cancer
- 2.5K Triple-Negative Breast Cancer
- 13.1K Day-to-Day Matters
- 132 All things COVID-19 or coronavirus
- 87 BCO Free-Cycle: Give or Trade Items Related to Breast Cancer
- 5.9K Clinical Trials, Research News, Podcasts, and Study Results
- 86 Coping with Holidays, Special Days and Anniversaries
- 828 Employment, Insurance, and Other Financial Issues
- 101 Family and Family Planning Matters
- Family Issues for Those Who Have Breast Cancer
- 26 Furry friends
- 1.8K Humor and Games
- 1.6K Mental Health: Because Cancer Doesn't Just Affect Your Breasts
- 706 Recipe Swap for Healthy Living
- 704 Recommend Your Resources
- 171 Sex & Relationship Matters
- 9 The Political Corner
- 874 Working on Your Fitness
- 4.5K Moving On & Finding Inspiration After Breast Cancer
- 394 Bonded by Breast Cancer
- 3.1K Life After Breast Cancer
- 806 Prayers and Spiritual Support
- 285 Who or What Inspires You?
- 28.7K Not Diagnosed But Concerned
- 1K Benign Breast Conditions
- 2.3K High Risk for Breast Cancer
- 18K Not Diagnosed But Worried
- 7.4K Waiting for Test Results
- 603 Site News and Announcements
- 560 Comments, Suggestions, Feature Requests
- 39 Mod Announcements, Breastcancer.org News, Blog Entries, Podcasts
- 4 Survey, Interview and Participant Requests: Need your Help!
- 61.9K Tests, Treatments & Side Effects
- 586 Alternative Medicine
- 255 Bone Health and Bone Loss
- 11.4K Breast Reconstruction
- 7.9K Chemotherapy - Before, During, and After
- 2.7K Complementary and Holistic Medicine and Treatment
- 775 Diagnosed and Waiting for Test Results
- 7.8K Hormonal Therapy - Before, During, and After
- 50 Immunotherapy - Before, During, and After
- 7.4K Just Diagnosed
- 1.4K Living Without Reconstruction After a Mastectomy
- 5.2K Lymphedema
- 3.6K Managing Side Effects of Breast Cancer and Its Treatment
- 591 Pain
- 3.9K Radiation Therapy - Before, During, and After
- 8.4K Surgery - Before, During, and After
- 109 Welcome to Breastcancer.org
- 98 Acknowledging and honoring our Community
- 11 Info & Resources for New Patients & Members From the Team