isolated tumor cell

2

Comments

  • xtine
    xtine Member Posts: 131
    edited March 2011

    I asked the same question, painterly, in a similar thread on the DCIS forum. The answer I got, which seems correct: "The difference between isolated tumor cells and micromets is size. Anything less than 0.2 mm is isolated tumor cells -- if it is larger than that it is micromets. ITC's are considered node negative. But micromets will move you up to node positive."

  • barbe1958
    barbe1958 Member Posts: 19,757
    edited March 2011

    ITC's can be circulating anywhere in your body, not just your breasts. In fact, we all have some in us at all times and something 'turns' them on - then the cancer delveops. A micromet is a breast cancel cell(s) that has detached from it's primary source and is caught by a lymph node. Some cells travel through our blood stream and set up home somewhere else to develop.

    So, I had both in my pathology report. The ITC was found in normal breast tissue and the micromet was found in two matted nodes.

  • renmars21
    renmars21 Member Posts: 55
    edited August 2011

    Hi Everyone!

    I had a Uni Mx in January for what was believed to be extensive DCIS, after final pathology came back my report showed a 1.1 mm area of IDC, grade 2 and a .08mm invasion to 1 lymph node.  I am showing Lymph Node negative but  i+,SN.  My Oncologist is wanting to send it for an Onco score test. Can they test such a small amount of IDC as he is stating depending on what my score is will determine if I need chemo.  My BS has said all along that I won't need chemo for a small tumor.  Im so confused.

  • bdavis
    bdavis Member Posts: 6,201
    edited March 2011

    So...

    ITC is less than .2mm and is = to node negative

    Micromet is between .2mm up to 2mm and is = node positive, but with same prognosis as node negative

    Macromet is greater than 2mm = node positive

    right?

  • SunnyCoconut
    SunnyCoconut Member Posts: 350
    edited March 2011

    Here is another terminology bit that confuses me.  I was told that my SNB was negative but there is some microscopic involvment.   What does that mean?  is that smaller than a micromet or is it a micromet?

  • bdavis
    bdavis Member Posts: 6,201
    edited March 2011

    Ask him what size, then you'll have your answer... Mine was .38mm and is called a micromet as it falls within the range... of course had it been .18mm smaller, it would have been considered node negative.

  • painterly
    painterly Member Posts: 602
    edited March 2011

    Thanks ladies re the difference between itc and micromet.

    I had an itc in the one node which was removed. It showed negative at the time of the op but when it was sent away for further testing showed an itc. I wasn't told the size. The onc. recommended 4 rounds of chemo which I didn't want but because I knew nothing about bc just accepted my fate. My tumour was 7mm.

  • Chocolaterocks
    Chocolaterocks Member Posts: 364
    edited March 2011

    My invasive bc was 3.8mm total and I convinced the MO to do oncotype testing- which I found out last week was approved by my insurance and now I am waiting the results which I understand can be 2 or 3 weeks

    My ITC were a total of less than 200 cells- but what I am confused on is:

    I thought they are considered

    cancerous cells?

    If I am wrong please correct,

    I am sorry I do not know whta a micrmet is.

    thanks all

  • bdavis
    bdavis Member Posts: 6,201
    edited March 2011

    A micromet is a small cancer cell(s)... trace amount

  • barbe1958
    barbe1958 Member Posts: 19,757
    edited March 2011

    Hopeful, an honest mistake I made, sorry! I even thought of correcting it, but the conversation moved on...

    So then it's worse than what my doc told me. I had ITCs and micromets with no further treatment! He told me to "save the big guns for next time".

  • mymountain
    mymountain Member Posts: 184
    edited March 2011

    Chocolate,

    They tell you 2-3 weeks for oncotype results, but just about everyone that I've had known, gets them in 12-14 days.  Like everything I'm sure it depends what day of the week it is sent, and recieved.  Onc would only give the results in person-no phone call.

    Hope your wait is short and your score is low!

  • bdavis
    bdavis Member Posts: 6,201
    edited March 2011

    Barbe... I had a micromet and am in chemo... with no regrets

  • barbe1958
    barbe1958 Member Posts: 19,757
    edited March 2011

    bdavis, I had expected chemo, but my surgeon had emergency heart surgery and the ball got dropped! Even the onc that I saw 9 MONTHS later said that I "fell between the cracks"! Trust me, I feel like a ticking time bomb....

  • bdavis
    bdavis Member Posts: 6,201
    edited March 2011

    Barbe... Maybe inquire about scans and then chemo now?? Can it really be too late?? I know oncs try to get chemo in within 6 weeks of surgery, but if its late chemo vs no chemo, maybe late chemo is a good option.

  • barbe1958
    barbe1958 Member Posts: 19,757
    edited March 2011

    I am WAY past the time for chemo!! Chemo has to be done within 3 months of surgery. I had my masts Dec 2008.

    I've had scans, but being ER+ know that my risk rises as time goes on. ER+ cancers are slower growing so take longer to recur.

  • bdavis
    bdavis Member Posts: 6,201
    edited March 2011

    I don't know what to say... Have you asked an onc about this, more recently... I understand the time frame, but let's say a rogue cancer cell did escape, which is unlikely, but let's say... the chemo would kill it before it lands on a lung or bone... so if scans are clean, then is it really really too late?

  • Snobird
    Snobird Member Posts: 593
    edited March 2011

    What no tamoxifan? I thought that was almost standard for ER+.

  • barbe1958
    barbe1958 Member Posts: 19,757
    edited March 2011

    Nope, no Tamoxifen, no AI's, NOTHING!!! (I had a hysterectomy years ago, and at (now) 53, they assumed I'm post-menopausal) I just sit and worry over every little bump and ache. I try not to dwell on it...but really, of course I do!

    My scans aren't always clean, either. I have areas that light up, but they feel those are arthritic so I just keep holding the faith.

  • bdavis
    bdavis Member Posts: 6,201
    edited March 2011

    I would investigate.. maybe with a differnt doctor... Maybe hormone therapy now, not TAM but the post-menapausal version... and maybe even chemo...????

  • Rachel1966
    Rachel1966 Member Posts: 100
    edited March 2011

    I had my first chemo treatment 5 weeks to the date of my bilateral mastectomy.  My first path report said micromet on a side where it was only dcis... Second path report said isolated tumor cell with dcis and lcis... My oncotype was 26.  Without chemo I was at 17% of reoccurance.  With chemo and now Tamoxifen, I'm assuming that went down to 5%? 

  • Chocolaterocks
    Chocolaterocks Member Posts: 364
    edited March 2011

    You people are amazing- I always learn so much.   Okay- so tomorrow I call and make appointment with onc for approx March 17th because results could not be given over the phone or get close to that date- thanks!!

    Ofcourse I will provide results.

    Went for my v, ultrasound today, bloodwork to determine later if I go into menopause and dropped off rx for tamoxefen.

    34 days since surgery- so I am making progress

    Had  the rest of my chocolate turnover!!

  • barbe1958
    barbe1958 Member Posts: 19,757
    edited March 2011

    I see my onc again in June and will ask about a hormonal. I've made it this far...and I'd like to go a bit further! I may be one of the lucky ones that goes 25 years after surgery, but we never know - do we? I am interviewing for a new job today (gets harder over 50 to have anyone want you) so I am certainly not living my cancer, if you know what I mean....I'm just living!

  • bdavis
    bdavis Member Posts: 6,201
    edited March 2011

    Be optimistic about your job... I am 48, and just had to quit one job because my main employer promoted me even with all my cancer baggage... knowing I will miss a ton of work for chemo, surgery etc... Sometimes older is more focused and driven... employers can recognize that... The 20-30 year old can have distractions with young children and job changing etc... have faith.

  • barbe1958
    barbe1958 Member Posts: 19,757
    edited March 2011

    I actually had a GREAT interview this morning and he told me my image is exactly what they're looking for in management! Woo hoo! Let's see if he can put his money where his mouth is....

  • bdavis
    bdavis Member Posts: 6,201
    edited March 2011
  • Chocolaterocks
    Chocolaterocks Member Posts: 364
    edited March 2011

    Why does there have to always be a stumbling block?

    Need to have endometrial biopsy based on v ultrasound

    Probably on the wrong thread

    Moved mo appointment

    I will let you know

    take care

    chocolate

  • barbe1958
    barbe1958 Member Posts: 19,757
    edited March 2011

    No thread is a "wrong" thread...not a stumbling block, an opportunity to make sure you have no problems elsewhere! Good luck, sweetie!

  • Cyborg
    Cyborg Member Posts: 848
    edited April 2011

    Ok. Now I am worried about waiting for chemo. So the standard is 6 weeks after surgery?!

  • barbe1958
    barbe1958 Member Posts: 19,757
    edited April 2011

    Standard is 3 months I was told.

  • bdavis
    bdavis Member Posts: 6,201
    edited April 2011

    I think it is preferred to be 6 weeks, because I had surgery on Dec 8 and was supposed to start chemo on Jan 10 and wanted to delay a week so I could have a colonoscopy and they allowed it, but wanted to get started.

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