help with side effects of taxol

Hi, I had my fifth treatment, but 1st of taxol a week ago and I felt fine at first, but then about the third day after, I got really bad joint pain.  I could hardly stand or walk or especially go up and down the stairs.  I am 42, usually have no such problems.  Is this normal for Taxol and has anyone else had the same problems.  I would love to hear of something that helps with this.  Thanks for any answers!

Jenny

Comments

  • krcll
    krcll Member Posts: 343
    edited March 2010

    Hi Jenny- Are you having Taxol every 3 weeks? I got it every week for 12 weeks- in the end you get the same amount of Taxol just a lower dose more often. Those of us that are on the weekly don't get such bad joint pain as the "every 3 weeks" women. When I was doing FEC and had Neulasta shots, I remember someone saying that Claritin helped for the joint pain. Maybe it would help you now? I got really uncomfortable, short of breath and extremely tired from the Taxol but never had more than a twinge of joint pain. Everyone is very individual in which SE's they experience.

    Just remember that you are more then 1/2 way through chemo and, even if it is hard to believe, you WILL be able to get through it!  Gentle hugs.

  • Leah_S
    Leah_S Member Posts: 8,458
    edited March 2010

    I had dose dense (every 2 weeks) taxol and got terrible pain - not only in my joints but also lower abdomen (ovary area) and all down my legs. Each treatment the pain was stronger so by the end I was using percocet.

    I wish you the best.

    Leah

  • NatureGrrl
    NatureGrrl Member Posts: 1,367
    edited March 2010

    Unlike most people, I had a harder time with Taxol (weekly) than with the A/C.  I also had significant joint and body pain from the Taxol; the good news was for me it didn't get progressively worse -- what I had after the first treatment or so was as bad as it got (which was more than enough!).  I took Lortab at night to give me relief so I could sleep but otherwise lived with it (trying to take heavy-duty drugs and drive/work would not have worked for me).  I took Claritin (generic, the non-D type) throughout my chemo and beyond (in fact, I still take it, but it's allergy season now!).  For me it helped a TON with the Neulasta pain but I don't know if it helped keep the pain down with Taxol (because I never stopped taking it to find out) but if your dr. doesn't have any objection, it can't hurt to try. 

    Talk to your dr. about a pain management plan; if one thing doesn't work, don't hesitate to ask for something else.  As mentioned, everyone is very different.  

    You'll get through it.  I started all this a year ago this week and although at times it felt like I'd never feel normal again, everyone kept telling me I'd make it... and I did.  Best of luck and a warm hug. 

  • fg2000
    fg2000 Member Posts: 30
    edited September 2010

    I had Taxol every two weeks (dose dense treatments) and I had terrible pain following every treatment. I literally could not get out of bed for nearly two weeks afterward. As soon as I began feeling slightly better, it was time for another treatment. I had a much harder time with Taxol than A/C and I was told it was the opposite with most people. I also had a Neulasta shot the day after each treatment which I'm sure didn't help. I was so happy to be done with chemo. Nasty stuff.

  • kittycat
    kittycat Member Posts: 2,144
    edited October 2010

    I have weekly Taxol treatments.  So far I am doing okay, but have mild pain in my joints a few days after treatments.  I started to get neuropathy in my toes about a week ago.  I hope that goes away.  My sister did dose dense Taxol and had much worse pain than me. 

  • slg2130
    slg2130 Member Posts: 140
    edited January 2011
    I start Taxol on 11-Jan, and my onc told me that if I have any kind of joint pain, she'll have me take glutamine.  Might be worth asking about that.  Was also told to start taking Vitamin E and B-complex now to help with any neuropathy that might develop.  Don't know if it will work, but I'm willing to try about anything to limit side effects!  Smile
  • monisch
    monisch Member Posts: 57
    edited January 2011

    hi ladies,

    fg2000;  I had same experience asyou. I had 3 taxotere sittings each sitting 3 weeks apart. The 3rd day after a sitting i had extreme pain in the legs, I could hardly walk. After the 1st round of Taxotere i had not only the pain in my legs but also sores in my mouth, swollen throat, so that i couldnt swallow, lost all taste buds, even water was horrible but i couldnt drink anything else. I had upper stomach pain etc.... Today 6 weeks after i got thru with all my chemo treatments, I still have numb feet , numb fingertips, leg pain, and now on the last three finger nails on the both hands a brown stripe across the nail. I was told the numbness in the fingers and feet can last several months. Good thing is though.. no more sores in the mouth and i can taste everything again..thank god.  One tip all of you:  please  be carefull with animal bites and scratches ( dogs and cats ), or any cuts and scratches for that fact. I had a small little hole from my puppy in my hand... playfully biting. Well this hole got infected and i ended up having a complete collapse. I was brought to the hospital and stayed over  4 days. My hadn was operated on 4 days after i was admitted. I was close to a sepsis due to the infection.  We are very subceptable to infections the week after taxotere....... BE CAREFULL.... If i wouldnt have collapsed, I may be dead now from a measly little bite from a puppy and not from my cancer !!

    I wish all of you going thru the taxotere good luck and hopefully you wont experience it as bad i have. But one thing is certain..you will get thru it.. I did and the light at the end of the tunnel of treatments is getting clearer. Im on my 3rd radiation treatment.. I have 38 in total. 

  • njbhwgirl
    njbhwgirl Member Posts: 295
    edited January 2011

    I finished taxol in August. I had it every other week 4x..I had joint pain from the first treatment. Unfortunately I have arthritis and I believe it accelerated what was there. Five months later and my left hip is still killing me. The bottom of my right foot hurts when I walk all the time. I did not have this pain prior to taxol

     Anyone six months out still having joint pain?

    I am going to my orthopedic tomorrow to see how bad the arthritis is, I feel another hip replacement coming..YUCH

  • TMarina
    TMarina Member Posts: 692
    edited January 2011

    I had bad bone pain with taxol (every 2 weeks x 4).  It started on the 3rd day and lasted about 4 days.  I took Percocet and it helped a lot--sometimes I needed 2 though.  With the percocet for pain, Taxol ended up being a lot easier for me than the AC.

    I had chemo last year (2009) for colon cancer also, and both times I finished chemo I had bad joint pain for a few months.  I had mild RA before, but this was worse.  I figured the steroids I get with chemo help, then when that's done everything came back full force--like a rebound.  I was going to start seeing a rheumatoligist again, but then I got bc.  Maybe this year... I've heard A LOT of women say their joints ache after chemo.

  • velicheto
    velicheto Member Posts: 1
    edited December 2011

     Hi Jenny.. I am on my third dose of taxol and I too have the horrible muscle and joint pain. Nothing seems to work for me either I just try to get through the day best I can with heating pad and hot showers.But there is one thing I keep telling myself. The pain I feel is the taxol killing the rest of the cancer thats there after the A/C infusions I had four of those and now four of taxol. I have one more left. I was told to take extra strength tylenol it just seems to take the edge off if I stay on top of it.give it a try...:)

  • NWArtLady
    NWArtLady Member Posts: 360
    edited December 2011

    I am doing Taxol right now and the oncology nurses and others have told me that if I were to feel any joint or muscle pain, to try Claritin.  I know, it sounds odd, but they say others have used it with success for pain!

    My primary side effect has been neuropathy in the fingers and toes.  It comes and it goes but it is not as bad as I have seen and heard from others and I attribute this to L-Glutamine twice a day (3 grams each time).  I also go to acupuncture every other week and she helps me with gastrointestinal issues, neuropathy, and anxiety.

    Hope this helps!

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