T3N1M0 is locally advanced or early stage?
Hello everyone
My mom was dx in November 2010 with IDC stage 3a BC. Since then I've tried to gather information about her desease as much as I can. As Patology said her breast tissue is clear and any vessel involvement isn't seen.She had 6cm tumor and 8 out of 35 nodes were positive. So does anyone know that she is locally advance or is in early stage. In some websites they mentioned stage 1, 2 and T3N1M0 are early stages. Is that correct or not.
Comments
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I always understood that locally advanced breast cancer is only stage IIIc, but I may be wrong. I thought that N3 is what makes it locally advanced.
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Your mom's oncologist will stage your mom based on scan results and path reports. Are those complete? Looks like she's stage IIIa. My understanding is that is early locally advanced. Concerning the web search, different sites define the IIIa stage. It's so nice you support your mom through her cancer journey. Hang in there, it can be a rough ride however there are great women on this site that will offer support. My prayers are with you.
Maureen
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Dear Maureen thanks for your answer. before surgery we did a CT Scan from her lungs. It was clear. But we didn't do any bone scan and I'm a bit concerned. But fortunately she doesn't have any pain in her bones. Her onc said it's stage IIIa. Everywhere I poked in said early stage breast cancer is curable.What about her stage?Do you have any idea about her case? Her doctor gave hope to her and said your results are OK.
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I believe that anything stage III is locally advanced unfortunately. Your mum seems to be stage IIIa, so locally advanced, but even so stage IIIa is in principle curable. I think you should go for a liver and a bone scan, too, in order to be sure that the beast has not spread. Hugs AgentMo
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I am stage IIIa and have thought of myself as locally advanced AND early. If the choices are just early or advanced (what I think of as stage IV) , then I think I am early. If you want to define more, I have thought that "locally advanced" differentiates having positive lymph nodes from those with negative nodes, without meaning that we are stage IV. It is true that the terms are used differently by different people and I don't really know what is "right".
If you are concerned about if it is curable, it can absolutely be beaten. Stage IV is a different can of worms, but at stage IIIa, for the majority of women, the first treatment will get rid of the cancer. It doesn't matter if it is called early or locally advanced!
If I have gotten any of the facts wrong, please correct me! This is just my personal understanding.
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Dear AgentMo Thank you for your advise. we did a sonography from her liver and doctor said it is safe and clear. The nly thing I'm concerned about is her bones. I am determined to ask her onc to do a bone scan this time when we go fo her check up.
Dear Krcll Thank you for your answer. I think the same way. The difference between my mom's case and stage IIb is 1cm excess in her tumors size. And there shold be differences between her case and some stage IIIa which has involvements in breast tissue, vessels and a lot of nodes. We should hope that in very near future the complete cure of cancer will be found. And there won't be any victims from this so called cancer
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Stage IIIA is still considered early stage.
Definition of early stage: http://www.cancer.gov/dictionary/?CdrID=446564
Detailed information on each stage:
http://www.cancer.gov/cancertopics/pdq/treatment/breast/Patient/page2 -
It does seem a bit confusing, I was dx locally advanced stage 3, My tumor was 4.5 cm and 10 pos nodes out of 17. However, I see some times gals with bigger tumor and more nodes in a earlier stage. Sherri, maby you could shed some light on this? My feeling is the same as the other women though this is treatable and your mom can beat this! She will most definitly
be in my prayers, your a great daughter!
Faithfulheart
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Thanks Sherri,
I'm happy to Know I'm not the only one that noticed that. Hey Mabey were no stage cause the beast is gone!!!
Big hugs to all!!
Faithful
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faithful, i think it also depends on where the positive nodes are - i had a 2cm tumor and one positive node, but because it was a supraclavicular node it automatically threw me to IIIc and locally advanced, and it couldn't be operated on until after i had chemo (don't remember why - the BS and MO both explained it at the time). I did read somewhere that "locally advanced" used to be under stage IV, and then they saw that locally advanced statistics were closer to other stage III then Stage IV, so they reclassified it to stage III.
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When I was first diagnosed I am certain my oncologist told me I was stage IIb. But, if you look at my signature line, clearly, I am IIIa. I read somewhere that the staging categories changed around the time I was diagnosed so maybe that's why. A couple yrs. ago I asked my rad. onc. what stage I was (notice I said WAS) and he looked at my chart and said, "stage III". I am glad I thought I was a lower stage when diagnosed. I think all along I knew I was stage III but did not really want to ask for clarification.
BTW-I am coming up on 5 years!!!
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Stage IIIC here with internal mammary node, plus 9 other "regular" nodes plus a big tumor. I'm not sure how I feel about knowing that previously I would have been considered Stage IV. Maybe that's why my onc offered me an extra long appointment once my pathology was known. I declined that offer, because I really didn't want to hear how bad it was, only how she was going to treat me.
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I know for sure that staging has changed in 2002 or 2003. Before 2002, all patients with positive axillary lymph nodes were regarded N1 and hence stage II. This definition has been changed, now N2 start with 4 positive lymph nodes. Therefore, those with more than 3 positive lymph nodes today would all be classified as stage III. The location of the positive nodes matters for the N3 classification and hence for the distinction withing stage III.
Caaclark, I certainly would also feel better being stage II. Unfortunately, by now I have dwelved too much into the topic. Glad you are approaching five years.
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When I was Dx in feb 2006, onc referred to stage 3 at late or locally advanced (don't remember the exact term), but stage 3 was not early stage BC...as long as we are NED, I guess it doesn't matter what stage we were (do I really believe this!!!)...except for the fact that we worry...especially when your onc gives you stats.....BC is not in the forefront of my mind when I go to bed and when I wake up, but the worry is never far away.....
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According to BCO,
http://www.breastcancer.org/symptoms/diagnosis/staging.jsp
wherever axillary lymph nodes are mentioned for the stages they distinguish whether they "are clumped together or sticking to other structures", otherwise they just say axillary nodes without mentioning any specific number of nodes, so it seems it's the progression of cancer in the nodes rather than the number that affects prognosis and treatment.
Stage IIb `... and has spread to the axillary lymph nodes."
Stage IIIa `... and has spread to axillary lymph nodes that are clumped together or sticking to other structures."
When the tumour is larger than 5cms it belongs in IIb if there are no nodes and IIIa if nodes have "clumped or stuck" but then there is nowhere when nodes have not "clumped or stuck" with a tumour greater than 5cms. Of course there are other reasons for staging not affected by the nodes. I assume these changes are the result of prognostic statistics gathered from many studies and wonder why they haven't been more widely publicised.
I know one of my cancerous nodes had ruptured but have no idea whether that puts me in stage II or III.
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Hi SheilaE; I don't know; it is all a bit confusing for me; if this helps with your 'figuring out'. I was diagnosed with Stage IIIA Invasive Ductal Carcinoma, my tumor was 7.5! in diameter (which my onc said was equivalent to small grapefruit) After TAC Chemo/Surgery#1 to remove the tumor that chemo had shrunk to about the size of the tip of a pen(my surgeon removed 4 lymph nodes I think, and they tested negative for cancer; so it had not spread into the lymph nodes/Surgery #2 to remove additional calcifications/cancerous tissue found in previous/More TAC Chemo/Radiation/Now Arimidex. I felt that I was very lucky to have found out in the 'nick' of time since Stage IIIB is, from what I learned, not much can be done; the cancer has spread to the chest wall and other areas of body. (So you don't know if you are stage II or III? Has your onc not told you or done the staging process?)
God Bless you!! Take care now!
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My original tumor was over 4cm IDC, 1cm ILC, and DCIS all in one breast and after full axillary lymph nodes dissection I had 3 pos and 2 clumped (grouped together) that were possitive, And it also mentioned extracapsular extension. Im not sure if it was in my superclavical area but I do remember them saying something about that, and they are highly radiating that area right now. But it was after the discussion about the poss group of nodes that made me understand that I was Stage 3b. I did have neoadjunctive dose dense chemo, bilat mast with expanders (did find precancer in other breast too) having rads and may also have a ooph and then switch out expanders for silicon in a few months. But the stage still does scare me now that most of my active treatment is almost over.
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...and a PET/CT Scan was ordered immediately by my onc, during my staging process. I have since had a couple more tests (I think it was the Nuclear Bone Test, don't remember, but I do remember fasting and drinking a contrast before the test/and having to hold my bladder! ha) The tests are worth the un-significant 'hassle' because they give us re-assurance when we get good results!
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Margie, yes, I was told it was stage 3 but I don't know whether I should be stage 2 with the new rules. They probably have different criteria here in Australia anyway but if the prognosis has now been improved I'd love to be stage 2 for my own peace of mind.
Tammy, that's what my pathology said, extracapsular extension, but I don't know what it means or if it fits the new category for stage 3. I suppose I could see if adjuvant online gives me different statistics now if they take into account the new information but the thought of going to that site gives me the creeps.
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Dear lago thanks for your information. I checked them and I saw what I want to see.
Dear Sherri this time when we take her to the onc we ask him for bone scan. You know it's a bit scarry. But it's something we should do.
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@Sheila: The staging information that you have posted is the old staging information (today it is only used for the clinical staging, but not for the staging after pathology). Today's staging can for instance be found at the American Joint Committee on Cancer. One possible link is the following: http://www.cancer.org/cancer/breastcancer/detailedguide/breast-cancer-staging
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Sheila, my BS pretty much thought I would be a stage IIIA because he really thought there would be a micro-invasion in my node(s) and of course my tumor size (and grade). I ended up a stage IIB because my nodes were clear. I'm sure if my nodes where not clear I would be getting radiation. I was in a grey area and my rad onc felt the risk out-weighed the benefit considering all the other aggressive treatment. So as you can see they must draw lines but sometimes there isn't a huge difference.
Bottom line is we really need to look at staging as a guide for being treated and not how likely we are to recur.
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The NCCN Treatment Guidelines are updated every year. V2-2011 is the most current. Their info on staging is on pages 61 - 63. It is necessary to register to view the physicians version of the guidelines:
http://www.nccn.org/professionals/physician_gls/PDF/breast.pdf
Staging is a guide for treatment. The decision of whether to recommend any particular treatment is based on an weighting of the benefits of the treatment vs. the risks from the treatment. While the risks of most treatments remain consistent regardless of the diagnosis, the benefits change as the diagnosis/staging changes. The way that staging is set up, those conditions that put the patient at higher risk of recurrence (and particularly, distant recurrence) are placed in higher stages. For example, all T4 tumors, which are tumors with an extension to the chest wall or the skin, are Stage IIIB, regardless of the size of the tumor or whether there is nodal involvement. Similarly, all women with N2 nodal status (4+ nodes) are Stage IIIA (or higher) regardless of the size of the tumor. This is because studies have shown that recurrence risk increases when more than 3 nodes are affected.
So staging unquestionably is also an indication of the likelihood of recurrence. To suggest otherwise is simply wrong. At time of diagnosis, those who are higher stage have a greater likelihood of recurrence. Based on this greater likelihood of recurrence, the "benefit vs. risk" equation from certain treatments swings in favor of the "benefit" and therefore these treatments are more likely to be recommended for those who are higher stage. Because these additional treatments are given, those who are higher stage may be able to reduce their risk of recurrence to levels that are similar to those who are lower stage who do not get these same treatments.
Sorry for intruding on this Stage III discussion and into the Stage III forum but I thought the NCCN Physician's Guide staging info might be helpful and might clear up some of the confusion. And I felt the need to comment because my head explodes when people say that staging doesn't matter.
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Beesie I think you misunderstood my post. Of course higher stage means more likely to recur but that's why the treatment is more aggressive. Treatment lowers the risk of recurrence and that's why the focus of staging should be on treatment.
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lago, there has been so much discussion on this board lately about the fact that "stage doesn't matter" that I think the point that you just made needs to be explicitly stated. That's what I tried to do. Stage matters. We are not all alike. That's why we get different treatments. And the fact is that even with these treatments, the overall recurrence rate increases as stage increases. So while these additional treatments are effective at eliminating some of the differences in recurrence risk between the stages, unfortunately they are not effective at eliminating all of the differences. Might there be a blurring of the line between some of the stages? Of course, but that doesn't change the fact that overall and on average, there is a difference between the stages.
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Again I don't think I'm saying anything different. I'm not denying the difference but stating the focus should be on survival and what needs to be done to survive instead of focusing on "when will I die" With treament the stats are in favor of survival for most stages.
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It's times like this I wonder what a stage I BC is doing on the III site. We are in a crappy boat, but bottom line is it is more likely we will die of something other than breast cancer (even at 51%). The number of nodes does come into play, but once the cancer is removed we are just as "cancer free" as the stage I girls. It's about looking at the bright side instead of focusing on the what if's.
The recent blog about stage forums and whether or not they should restrict postings to girls of that stage is just because of moments like this. Thank God for Beesie that she was so lucky to be at stage I, but we weren't all so lucky and we'd like to put on some rose colored glasses when it comes to staging issues. Sure our dice aren't as lucky as hers, but we are still rolling the dice just like she is. Give it up girls. Stage doesn't matter after treatment is over...you either recur or you don't. I'm banking on never fighting cancer again because I don't like the other option. If it happens well pooo, but for now all I can do is live EXACTLY LIKE THE STAGE I GIRLS. Ok now we do have something in common.
Sorry, I just got my gripe on. Lago I'm very likely to see you posting in 10 years and I look forward to it!
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You said it DCMom, I'm with you on this one. Also need to respond to dobbins_margie's statement that beyond stage IIIA, "not much can be done" and that she caught hers in the "nick of time". So does this mean I didn't and that's that for me? And really? You are really going to say that on a board filled with stage IIIB's, IIIC's? Not only is this wrong, it's inappropriate to say the least.
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Also need to respond to dobbins_margie's statement that beyond stage IIIA, "not much can be done" and that she caught hers in the "nick of time".
I was wondering about that as well. Whatever our private thoughts might be about our dx, as members of the Stage III board, we encourage each other with our posts.
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DCMom I expect we will both too busy living our lives to be posting here in 10 years ;-)
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