ALTTO Trial

Options
mariemarie
mariemarie Member Posts: 5
edited June 2014 in HER2+ (Positive) Breast Cancer

Is anyone on this trial? It compares Herceptin with Lapatinib, both start at the same time as Taxol.

· Share on FacebookShare on Twitter

Comments

  • olduser
    olduser Member Posts: 24
    edited June 2009

    My partner, Joyce, is on the trial. She has arm three - Herceptin followed by Tykerb (lapatinib).

    Mary

    · Share on FacebookShare on Twitter
  • MsDebS
    MsDebS Member Posts: 36
    edited July 2009

    I am in the trial...got arm 1.  Just doing Herceptin now every 3 weeks.  Side effects are minimal for me.  I get winded easily, my eyelashes and brows fell out, I have gained weight and my nose runs at the most inconvenient times.  But it is so much better than the Taxol.  I also have problems with urinary tract infections from the H so am on a maintenance dose of cipro.

    · Share on FacebookShare on Twitter
  • runnerlori
    runnerlori Member Posts: 15
    edited July 2009

    I am in the trial but have not been randomized yet... So far I have had 3 cycles of Adriamycin and Cytoxin.  One to go! YAY... then I will be randomized.

    I feel pretty good. Next I will get either taxol, every week for 6 weeks or taxotere every 3 weeks for 3 months.   Any suggestions or input? thanks...

    · Share on FacebookShare on Twitter
  • krcll
    krcll Member Posts: 343
    edited September 2009

    Hi all!

    I have gotten the offer to do the trial and I need to decide by tomorrow. What do you know about Lapatinib (Tykerb)? What made you decide that this trial would be good to do? I am just sitting down to find out what I can on the internet, but I would really appreciate it if anyone had some information. Thanks!

    · Share on FacebookShare on Twitter
  • krcll
    krcll Member Posts: 343
    edited October 2009

    I'm just wondering how everyone is doing? I am on this trial and will be randomized soon. I've done 2 x FEC 100 so far. Two more to go and then Taxol + Herceptin or Tykerb.

    · Share on FacebookShare on Twitter
  • rachelann
    rachelann Member Posts: 1
    edited August 2010

    I started the trial July 26th and am on arm 2.  I get 6 cycles of taxotere and carboplatin, at 3 week intervals, and will be on Tykerb daily for one year.  The Tykerb dose is 750 mg during the chemo cycles and will then be increased to 1500 for the last six months.  I was, of course, hoping to get placed in arm 4, where they get a full year of both Herceptin and Tykerb, but at least am glad to get the Tykerb.  Rachel   

    · Share on FacebookShare on Twitter
  • krcll
    krcll Member Posts: 343
    edited August 2010

    Welcome Rachel! I also got the Tykerb arm only and at first was disappointed. But I am betting that Tykerb is going to prove itself better (crossing the blood/brain barrier) than Herceptin so feel lucky. For a long time I was thinking of withdrawing from the trial after 6 months so I could get 6 months of Herceptin as well (I know- not very ethical). But then my liver numbers started going up and I was in danger of being thrown off the trial- then I really wanted to stay on the trial! We Tykerb women are so lucky because we can always go over to Herceptin if something happens with Tykerb, while the Herceptin women have no back-up (if they aren't on a trial).

    Good luck with any SE's you have and feel free to PM me!

    · Share on FacebookShare on Twitter

Categories