Help me understand lab results

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debpurple
debpurple Member Posts: 16

I just went to doctor to get a copy of biopsies. I do have IDC. The invasive tumor is .7cm

Nottingham score 5/9(nucluer grade 2, tubule score 2, mititic score 1

Estrogen &  progesterone receptor analyses & evalution of Her-2/neu overexpression are being performed on invasive tumor.

Doctor said that I was hormone sentive and I could go on hormone type pills later and would stay on them for 5yrs. 

Anyone understand all this?

I go to PS Monday and talk about mast. And then he will get with my dr to set time up for surgery. Both will be there to do everything at once. He will check lipnos then.

Thanks!

Debra

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  • pj12
    pj12 Member Posts: 25,402
    edited June 2010

    If bad news can be good, yours is.

    The "stage" of your cancer is determined by the size of your tumor  (.7cm-that's small), if any lymph nodes are involved and whether there is any spread to other places (metastasis). You can't know all until after your surgery. But the small tumor size is one piece of good news. Will you have a pre-surgery work up looking at lungs, liver and bones? I think that is standard. They will look at the lymph nodes at your surgery time.

    The "grade" of your cancer is determined by your Nottingham score. It tells you how aggressive your cancer is.  5 is grade 2 and you have a low mitosis rate so your cancer is not very aggressive.  That's also good.

    Estrogen, progesterone and HER-s analysis will determine if your cancer will respond well to hormone therapy. Do you mean your Dr already knows that you are ER+? If you are you will benefit from some of the newest drugs to fight recurrence.

    Has your Dr already recommended mastectomy? Lumpectomy is a reasonable alternative in many cases but does almost always require follow up radiation. You need to do a lot of reading to make an informed decision.  

    There is a lot to be learned from the good women of this site. Ask anything and someone will know!  Best wishes.

    pam 

  • pj12
    pj12 Member Posts: 25,402
    edited June 2010
  • debpurple
    debpurple Member Posts: 16
    edited June 2010

    He said i was positive but The paper said Her-2/neu so I am confussed. I called him and my family dr of course neither was in today but they are suppose to get with me to help answer my questions.

    The size of it is confusing because he only took some of the core when he did the bio. So is the report talking about the mass he took or my lump that is still in my breast? 

    I am reading anything I can find and this web site has helped but I am still confused. I will keep asking until I find the answers.

    Thanks for the help

  • pj12
    pj12 Member Posts: 25,402
    edited June 2010

    You can be ER+ or ER-; PR+ or PR-; and Her-2 + or -.  It's the ER and Her-2 that are most important for your treatment plan.  The final size is calculated at surgery. So bottom line... final word comes after surgery. 

    Please ask why mastectomy is recommended.

    Good luck!

    pam 

  • dlb823
    dlb823 Member Posts: 9,430
    edited June 2010

    debra ~ Pam has given you excellent information.  In addition, you need to understand that accurately determining whether Her2 is + or - is extremely important to the treatment that will be recommended for you.  Her2+ can be a more aggressive bc, and so a drug called Herceptin is often given to women who are Her2+.  But sometimes initial lab pathololgy isn't fine tuned enough to tell whether someone is truly Her2 - or + without further testing, so your doctor will send out for a more definitive test that is referred to as a "FISH" test.  It sounds like this is what your doctor has done.     Deanna

  • debpurple
    debpurple Member Posts: 16
    edited June 2010

    I will be going to PS on Monday then my family Dr on next Thursday. He will help answers my question. I want to see if I need to go to a breast surgeon or surgeon oncologist. Cause the Dr I'm seeing is a cancer specialist but not just breast. Thanks for all the info. it sure does help. I want to make sure I get the best care possible. Thanks!

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