5-HTP and L-Tyrosine for depression
Has anyone taken 5-HTP and L-Tyrosine for their depression during their cancer experience? I just started taking it yesterday and was wondering if anyone has had success with them? How much did you take and are there any warnings about them after chemo or radiation? I'm at my wit's end because I cannot tolerate prescription meds. Please tell me how you responded to this therapy if you've tried them and if they worked for you. Having a rough go of it right now. Don't know if its a mixture of the herceptin and the last blast of Taxol that has made me feel this low or am I really going mental?
Comments
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Before you do anything, please check with your oncologist to make sure there won't be any adverse reactions. Good luck
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Annettie, I once used St. John's Wort which was helpful. Flax oil is good for the omega 3s which help depression. I take flax oil capsules twice a day.
The most qualified person to assess your situation is a Naturopathic physician. Unfortunately, oncologists are not trained in these kinds of therapies. I have only tried 5 HTP for sleeping and it was helpful.
I'm sorry you have to go through this low time but there is light at the end of the tunnel.
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That's interesting you mentioned those; I just bought some a couple of weeks ago, not for me, but for my husband who takes medication for anxiety (we're hoping to transition him to something natural). How did you hear about those supplements? I found out about them from a book by Julia Ross called The Mood Cure. I didn't think about them in relation to depression (my depression has cleared up now that I'm taking iodine and eating pastured eggs -- I really think one or both those things has made a big difference!).I did take some 5-HTP one night when I was feeling anxious and needed to sleep... it seemed to have helped for that.
edited to add: That is interesting about omega-3's... there are lots of omega-3's in the pastured eggs I eat as well as DHA, another nutrient whose deficiency can cause depression. I also eat flax oil every day as part of my Budwig breakfast. Maybe that's why I'm not depressed, whereas before my cancer diagnosis I was HORRIBLY depressed!
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Julia, that's funny because I got a mood jolt from taking the iodine loading test where you have to take 50 mg Iodine the morning of the test. That day I felt in such a good, energertic mood. The doc said I really must have been deficient to notice the effect within hours. She said only about 10% of her patients report an immediate surge.
Vitamin D helps with SAD (Seasonal Affective Disorder) depression too. So maybe Annettie, you could try that too. Even tho it's summer, your D levels might still be low.
Julia, I have been cheating with the Budwig Protocol and take the capsules with yogurt and hope they get mixed in my stomach.

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I tried 5-HTP but got horrible stomach aches so I quit. Did not notice any effect. I did see some improvement with St. John's Wort, but again had side effects (can't remember exactly what, but it's been a while). Interestingly, SSRIs have been way more tolerable for me than the supplements, both side effect and effectiveness-wise.
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I've tried 5 HTP together with St John's Wort (my PCP), Sam-e was also mentioned (nutritionist who works with me PCP) but I never tried it. Was also taking Sedalia (by Boiron). I was taking all this stuff for stress, which may or may not have included anxiety and depression (most likely it did).
I didn't notice any benefit (or side effects) from the pills, though it's possible I wasn't taking the required dose (for instance if I was supposed to take pills 3x a day, I probably only remembered in the am.)
Best of luck.
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Wow, Lucy, that's so interesting! I had no idea that iodine supplementation could have that effect (nor did I realize how deficient I was)... really interesting that I'm not the only person it affected that way.
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I've taken 5-HTP also to fall asleep better, and I found it helpful. I'm also taking l-tyrosine currently. I had tried it in the past and got an upset stomach from it. It's a precursor to the thyroid hormone thyroxin, and I've been trying a loooong time to get my thyroid coaxed into gear. This time around, I make sure to take it with food, and that seems to be enough to prevent the upset stomach.
I first started learning about amino acids when I went to Dr Gabriel Cousens tree of life website. A short video showed him talking about the endocrine system and getting it balanced with amino acids, and that got my attention pronto. I went to the library to get his most recent book, but all the library had was "Depression-free for Life".
I encourage you to learn about the amino acids and how they play into the balance of our bodies. What you need will depend on where your deficiencies are. For some people, they're depressed because of too little seratonin. But there's also dopamine and norepinephrine that play important roles in how we feel. It's been a while since I read Cousens book. It's thorough in terms of saying what to balance, but short on how to determine where the deficiencies are.
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althea-
There is a urine test that can measure your neurotransmitter levels - my son has anxiety and depression issues and his doctor uses a test from Neuroscience to monitor his levels and then adjust his amino acid supplements accordingly.
BTW - Congrats on your5 YR Anniversary. You are an inspiration!
Beth
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Althea, do you think the tyrosine helped get the iodine working better? And belated congrats on your big anniversary!
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It's possible that the tyrosine is getting my thyroid to work better. I've been supplementing with iodine for 18 months now, anywhere from 50-100 mg/day. Iodine is really the only thing I stick with over the long run. Whenever I try something new, I give it a minimum of 30 days, usually 60, to see if I feel any better. By that standard, I would've ditched the iodine a long time ago.
Recent changes I've made include: drinking herbal infusions every day, rotating through nettles, oatstraw, and red clover (started this in march); started taking tyrosine a few weeks ago; trying new dinner recipes from Dr Cabot's liver cleansing diet book about 6 weeks ago (no dairy, no red meat, lots of veggies, everything from scratch). I've been steadily cleaning up what I eat and drink since I finished radiation, and at that time I started walking every day 30-40 minutes. And during the last 4+ years, my weight would go up easy enough, but getting it off seemed to require liposuction. Until Dr Cabot's recipes. Or the tyrosine. Or the iodine finally getting an upper hand on the receptor sites. I'm finally losing some weight, and I believe that's from the new recipes. The first 5 pounds came off before I started the tyrosine.
beth, do you have a link for finding those tests? I'm too broke to find a new doctor or even order my own tests online, but I'm making a list of what I want. That sounds like something I definitely want to have tested.
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althea -
Here is the link - there are a variety of neurotransmitter profile tests. I could not believe it - but BCBS actually paid for this test!!
https://www.neurorelief.com/index.php?option=com_content&task=category§ionid=12&id=40&Itemid=46
Beth
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Hello,
I just completed my radiation for breast cancer, i did not take L-Tyrosine while on radiation, as my doctor instructed me not to. However, I finished my radiation end of April, and I started back on L-Tyrosine. I take 1000 mg in the morning on an empty stomach then 500 mg after lunch. It has helped me greatly.
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Hello,
I just completed my radiation for breast cancer, i did not take L-Tyrosine while on radiation, as my doctor instructed me not to. However, I finished my radiation end of April, and I started back on L-Tyrosine. I take 1000 mg in the morning on an empty stomach then 500 mg after lunch. It has helped me greatly.
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