I am ER-/PR-, waiting on HER2...

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ebarb
ebarb Member Posts: 38
edited June 2014 in Triple-Negative Breast Cancer

There's chemo for us if we're TN, right?  Can someone tell me about those types of chemo?  Are they harsher than the others?  

I don't know when we'll know about the HER2 status but at this point I'm preparing for either.  I want to know all sides of this.

Thanks,
Erin

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  • jenn3
    jenn3 Member Posts: 3,316
    edited June 2010

    What seems to be the most common regimen for TN's is Adriamycin/Cytoxan and Taxol or Taxotere (AC + T).  Most get the AC dose dense (meaning once every two weeks) and it's mixed on the Taxanes, some get dose dense others weekly. 

    Good luck.

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  • ebarb
    ebarb Member Posts: 38
    edited June 2010

    Just found out I am HER2 postive... so herceptin plus others (THC? TCH?) will be my course of treatment.  We are not doing the ACT one because there are small chances of heart/bone marrow problems down the line.  This is info from the oncologist.

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  • suemed8749
    suemed8749 Member Posts: 1,151
    edited June 2010

    Hi ebarb - I was dx in Jan. 2008 with ER-PR-Her2+ IDC. Did Taxol/Carboplatin/Herceptin x 6 then Herceptin every 3 weeks for a year. It's a very "doable" chemo - I luckily had no major side effects and am doing well today. There's a great TCH thread here that was my lifeline during treatment.

    I'm in the Neratinib trial now - there seems to be SO much research being done on Her2+ with many new treatments coming. Wishing you all the best!

    (Edited to add that beautiful bride and happy mom pictures are the best!)

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  • spradhan
    spradhan Member Posts: 7
    edited August 2010
    Hi everyone:
    My mother was recently diagnosed of Stage 3, IDC, Grade 3 with multiple axillary lymph nodes involved. Her reports suggest ER/PR negative and HER-2-neu 1+ staining (negative). I do not understand the part of the report about HER2. Does it mean that it is only slightly positive so it can be considered negative and only work with chemo, or will HER2 positive drugs work for her. Also, her doctors are performing another test to reconfirm her HER2 status.

    Any information regarding this and possible treatment suggestion would be highly appreciated.

    Regards,
    Spradhan

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