Iodine / Lodoral and Potassium levels?

Options

My wife has been taking 50mg / day of Lodoral, potassium iodine supplement.  Today she had her blood tested and the doctor is urgently warning her to stop doing whatever is elevating her potassium level.  Apparently 1-5 units is acceptable and she is at 5.50.  They say that is borderline on needing hospitalization as it could cause heart murmurs and heart attacks.  Any idea if the potassium iodine could be the culprit?  She is quitting it immediately and hopefully her levels normalize.  She was tested yearly, and never had such an elevated potassium level.  They say its dangerous.  Any ideas?

«1

Comments

  • hlth4513
    hlth4513 Member Posts: 267
    edited April 2010

    Timothy-

    You might try posting at the IOdine Yahoo Group - the moderator, Steph, or  someone else there, may have the knowledge to help you.

    I take 100mg of Iodoral a day, and I was Ok on my last test 6 months ago. I know that sometimes it can be about balance between several minerals. For example,  I found out that my Selenium levels were too high (from eating so many Brazil nuts), that it had adversely affected and lowered my zinc levels.

    Good Luck!

    Beth

  • rreynolds1
    rreynolds1 Member Posts: 450
    edited April 2010

    I'm at work, but I'll check the potassium in my iodine supplement.  I have been taking it for several months and saw my oncologist and as far as I know my blood work was normal.  Interesting.  I'll post once I check my iodine supplement out.  I know it has selenium but mine seems to be normal.  Wow!  So much to balance in this journey.

    Roseann

  • Husband11
    Husband11 Member Posts: 2,264
    edited April 2010

    I'm skeptical that its the potassium in the iodine.  The iodine might contain tens of milligrams of potassium.  A normal diet included tens of grams of potassium.  Something doesn't add up.  I'm wondering if its the blood drawing procedure.  Apparently it was quite the ordeal, and from what I've read that can cause elevated potassium levels during testing that aren't present in the individuals blood.  Bev says it took them half an hour to get an incomplete draw of blood.  That might do it.  She should be retested when she's not dehydrated.

  • mathteacher
    mathteacher Member Posts: 243
    edited April 2010

    No matter how much potassium she consumed, her body's compensation mechanisms should regulate them. I have had blood taken when I was dehydrated and I instantly felt so ill I didn't think I could drive myself home. It was a sickening ordeal. I learned my lesson to be hydrated. Also, they can't find the veins/arteries easily if you're dehydrated so you may have to suffer multiple sticks.

    A half hour to take her blood? Poor Bev. That is way too much stress. If that situation ever begins to happen again, that is the blood draw begins to take more than five minutes, I would "abort the mission" as the NASA people say. Get out of there immediately. Don't be pressured to stay. Say Bev is sick and has to come back another day.

    Good luck.

  • thenewme
    thenewme Member Posts: 1,611
    edited April 2010

    Hi Timothy,

    Hyperkalemia is a very serious condition.  *Please*, for your wife's sake, DON'T rely on message boards and internet chat groups for this!  Potassium is used to stop the heart during some surgical procedures - it isn't something to take lightly based on skepticism.  Does the doc know she's taking Iodoral?   Maybe it could be the blood draw stress, but why would you even consider continuing to give her a "high potency" potassium supplement?   You should be double cheking everything she's taking to see if there is anything else in her regimen that contains potassium, and stop taking it until her levels are back to normal.  

  • Husband11
    Husband11 Member Posts: 2,264
    edited April 2010

    I agree Hyperkalemia is serious.  The iodine supplement only contains 21mg of potassium.  A banana has 200-300mg of potassium.  It doesn't fit in that the iodine is a significant contributor of potassium.  They say the average diet has 10,000 mg or more potassium per day.  What could 21mg do?

    They set up these annual physicals and ask you to fast from midnight onward.  So she didn't drink or eat anything before going in for the blood draw.  They couldn't get blood from her usual spots and had to prod and prod to get only a trickle.  So they used that trickle to complete some of the tests.  From what I've read on pseudohyperkalemia, stressful blood draws, extended tourniquete time and fist pumping all produce falsely high readings.

    Problem is, if she quits taking the 21mg of iodine and potassium and passes the next test, they will say "Aha, its the iodine".  When in reality, it could well be simply the blood draw technique.  She's been taking the iodine for nearly 5 months and never had a problem with potassium on previous tests done by the oncologist while she was on it.

  • Husband11
    Husband11 Member Posts: 2,264
    edited April 2010

    Added note:  She has a call in the the doctor.  She wants to let him know about the blood drawing episode.  He may not have been aware of the ordeal and its possible implications in the results.

  • mathteacher
    mathteacher Member Posts: 243
    edited April 2010

    Thank you Timothy for correcting thenewme on the potassium info. Iodoral is not a potassium supplement. A sip of orange juice would give you more potassium than Iodoral.

    Bev's reading also might be a lab error. My friend was hospitalized because his calcium came back very high. Turned out to be a fluke, everybody was upset. He was fine and has been jogging for the last ten years since.

  • thenewme
    thenewme Member Posts: 1,611
    edited April 2010

    Umm, mathteacher - www.optimox.com calls Iodoral a "High Potency Iodine/Potassium Iodide Supplement," and the label itself says the same thing.  It also says "Iodoral® is a precisely quantified tablet form containing 5 mg iodine and 7.5 mg iodide as the potassium salt."

    I won't go into the facts (or lack thereof) regarding Iodoral supplements here, but for the sake of Timothy's wife, I hope that caution and common sense prevail over using speculation and internet advice for treatment of a compromised patient with pathologically diagnosed mild hypokalemia.  Yikes.  

    Maybe it's a fluke reading, maybe it's inaccurate, maybe it was the stress, maybe she's taking something else with potassium, whatever, but I'm just stunned that continuing a potassium supplement would even be considered...??!  

  • mathteacher
    mathteacher Member Posts: 243
    edited June 2010
  • Husband11
    Husband11 Member Posts: 2,264
    edited April 2010

    I can't convince her to do otherwise than further discuss this with her Doctor.  On the subject of the potassium salt of iodine, potassium iodide, since the molecular weight of potassium (39) is less than 1/3 that of iodine (127), the mg of potassium in 21 mg of potassium iodide would be less than 7mg total potassium.  There's about 1/4 as much weight of potassium in KI as iodine.

  • mari55
    mari55 Member Posts: 693
    edited April 2010

    I would have the potassium level rechecked.  It is only slightly above the normal range and if her kidneys are working okay she should be able to get rid of any extra K+.  Sometimes if there is hemolysis of the lab sample there will be K+ released ( it is the primary electrolyte within cells) and it will falsely raise the level.

  • thenewme
    thenewme Member Posts: 1,611
    edited April 2010

    Hi Timothy,

    Did the doctor say when they want to recheck the blood work?  I've always been told that fasting blood work requires no food, but that plenty of water is advisable.  If she withheld liquids too, maybe the mild dehydration contributed to the elevated potassium reading (and definitely made the blood draw harder).  Hopefully the reading was a temporary one-time thing and will be back to normal on her recheck! Is she on any other medications or supplements that may contain potassium?

    I have a terrible time with blood draws, and increasing my water intake for a day or so before really does help.  Also, I'm not sure where your wife is in her treatment, but if she's doing or plans to do chemo, a port might be worth considering.  It makes both the infusions and blood draws infinitely easier, especially for those of us who are "tough sticks" to begin with.

    Best of luck! Your wife is fortunate to have you so involved with her care!  My DH was too, and I don't know how I could have done it without him!

  • Husband11
    Husband11 Member Posts: 2,264
    edited April 2010

    Bev's done chemo, almost a year out from it.  They had to draw blood from her other arm because her left side is off limits owing to the mastectomy and axillary lymph node removal.  She's awaiting a call back from the Doc, her GP, as to when she can get re-tested.  We are going through her diet carefully to see if anything contains unusual levels of potassium.  The fasting and not drinking water might be an issue where there is poor communication and instruction.  I was somehow under the impression that I shouldn't drink water before i come in, yet last time I was in I asked, and they said some water is ok.  For someone who is hard to draw blood from and may have been dehydrated the day before from the heat and exercise, its could be an issue.

     Thanks all for your thoughts and good wishes.  I'll let everyone know how she does on the next test, as I don't want to leave important issues left hanging.  We can all learn from each other's exeriences.

  • thenewme
    thenewme Member Posts: 1,611
    edited April 2010

    Aaah, so she's at about the same point as me, then. I'm almost a year out too.  And I'm keeping my port.  I also can't have sticks in the left arm, and had difficult veins to start with, so I definitely understand the blood-draw/IV trauma!  

    Definitely check to see if she can load up on water the day before.  Is there someone in her lab who has had good luck with her before?  I've gone so far as to reschedule a blood test to get the one person in the office who has been successful with my roly-poly veins.  At my oncology office, they have a "one-stick" guideline - if the person can't get it in one stick, they call someone else.  Also, always ask for the smallest needle (butterfly needle) - it may take a little longer after the stick, but it sure is easier!  For me, the standard needles always seem to "snag," but the butterfly or pediatric needles seem to go in smooth and easy.  I've found the lab techs at the oncologist's office to be generally much better at blood draws than the PCP office, so I try to have everything done through the onc.  

    Again, best of luck!

    PS - Mathteacher, nope - I'm no chemist or mathteacher and don't presume to play one on TV (or the internet)!  

  • althea
    althea Member Posts: 1,595
    edited April 2010

    I had a blood draw one time where hardly any blood entered the tube.  This was during chemo and I went round and round with the doctor who said I had to use labcorp the day before, and the chemo nurses who said they could do my bloodwork the day of through my port.  And thank goodness for my port and the option of doing bloodwork the day of because I was told the results of that one draw would not be reliable.  They called it hemolizing, not sure if I'm spelling it right.  My veins are still not the same as before, and I'm five years out now.  I dont' let anyone near my veins without a butterfly needle. 

  • Husband11
    Husband11 Member Posts: 2,264
    edited April 2010

    Well, Bev got retested yesterday.  Have heard nothing.  They have the wonderful system of, "We only call if there is a problem.".

  • mathteacher
    mathteacher Member Posts: 243
    edited April 2010

    Thanks for letting us know. I'm sure that must put your mind at ease. We all learned from this experience.

  • Husband11
    Husband11 Member Posts: 2,264
    edited April 2010

    I'll post again when we get something official.  As mentioned, I don't like to leave things hanging for someone who might be researching iodine and have it unnecessarily maligned.  The reason I posted this was to find out if anyone else had a similar experience.  There are women taking twice as much as Bev is, I'm sure.

  • carcharm
    carcharm Member Posts: 486
    edited April 2010

    How is her renal function? Hyperkalemia is a sign of renal failure.

  • Husband11
    Husband11 Member Posts: 2,264
    edited April 2010

    Renal function is tested regularly, as she is part of the Zometa trial.  Always tested fine.  Sure hope that's not the cause.  Hopefully its simply bad testing.

  • Husband11
    Husband11 Member Posts: 2,264
    edited April 2010

    A good ending to the story.  Doctor called today, her re-test scored her potassium levels as 4.2

    In hindsight, Bev was wise to refuse to stop taking all her supplements, which they placed the blame on. 

    That's nicely where it should be.  I can only conclude the first test was skewed because of the stressful manner of blood extraction.  I'm amazed the lab doesn't make a note of this for Doctors, so they can take it into account if the test results come up unusual readings.  I've read people are hospitalized for "Pseudo" hyperkalemia, in other words high potassium test results that are bogus.

  • mathteacher
    mathteacher Member Posts: 243
    edited April 2010

    That's great. If Bev had stopped the supplements, taking the advice of certain people not familiar with Iodoral, and then Bev got a normal retest she would have been misdiagnosed and lost the protection of iodine.

    I'm so glad you have read up on everything Bev is taking. Best to you both.

  • thenewme
    thenewme Member Posts: 1,611
    edited April 2010

    Awesome news, Timothy!  Thanks for sharing!  I'm so glad her retested levels are good! 

    Mathteacher - could you share your sources regarding "protection of iodine?"   I'd love to read more about it, since my research has not turned up any credible source for a recommendation for iodine supplementation, except in very specific medical situations.

    *************************************Quote******************************

    Cancer  (Source Here)

    The potential role of non-radioactive iodine in cancer care remains unknown. Antioxidant and anti-tumor effects have been proposed based on laboratory research. In contrast, some scientists have asserted that tumors may uptake more iodine than normal tissues. It has been suggested that high rates of gastric (stomach) cancer or low rates of breast cancer in coastal Japan may be due to high iodine intake, although this has not been demonstrated scientifically. Povidone-iodine solutions have been used as a part of alternative cancer regimens, such as the Hoxsey formula. Preliminary study has also indicated povidone-iodone solution as a potential rectal washout for rectal cancer. Overall, no clear conclusion can be drawn based on the currently available evidence.

  • mathteacher
    mathteacher Member Posts: 243
    edited May 2010

    Tim,

    How is Bev doing?

  • Husband11
    Husband11 Member Posts: 2,264
    edited May 2010

    Bev is doing well thanks.  The potassium scare was clearly some sort of anomoly.  She's suffering from fatique, the surgery, chemo and radiation (end of last summer finished) all seem to have a lasting effect.  She has more blood test tomorrow, as she is in the bisphosphonate trial, zometa arm.  Assuming the tests go well on Monday, then on Tuesday she will have another zometa infusion.  She's getting them at 3 mos intervals at this time.

  • dmorgan2
    dmorgan2 Member Posts: 241
    edited May 2010

    Dumb question....What is the best source of iodine OR where's the best place to get an iodine supplement and how much should we take? I really know nothing about it, other than we need it.

  • hlth4513
    hlth4513 Member Posts: 267
    edited May 2010

    Iodoral (tablet form of Lugol's) or Lugol's is the best form. It contains both the Potassium IOdide and Iodine.

    There is actually an entire iodine protocol that involves also taking unrefined sea salt, Vitamin C, Selenium and ATP co-factors(VitB2&B3).

    80% of breast cancer patients also have issues with the organification of iodine, so it behooves us to  take the ATP co-factors.

    There is a lot of good info and you can order the Iodoral and ATP co-factors at www.breastcancerchoices.org .  I strongly suggest also reading Brownstein's book on Iodine - Why You Need It - Why You can't Live without It.

    Beth

  • dmorgan2
    dmorgan2 Member Posts: 241
    edited May 2010

    Thanks, Beth!

    Do we have to be concerned about the potassium levels getting too high (from reading the comments here).

  • Husband11
    Husband11 Member Posts: 2,264
    edited May 2010

    The milligrams of potassium contributed by an iodine supplement are a drop in a bucket compared to the tens of grams of potassium in any healthy diet.  Its not a concern.

Categories