I have a new diagnosis!

No, I don't have any experience with my path results changing--gee whiz--you would never expect that one to happen!!!  But  . . . my path results came in as PR negative and ER only "weakly" positive.  Here's what my onc said about it.  She said she doesn't completely trust ER and PR results all the time because hormone receptors tend to be pretty frail and sometimes "break off" before the tumor is evaluated.  She said especially if the tumor sits for any length of time after a surgery (such as over a weekend after a Friday surgery--yep, mine was done on a Friday afternoon) that the results might come back lower than if it had been tested earlier. She said that hormonal status is probably underestimated in some cases, so in cases like mine (weakly positive) she tends to think I'm more positive than we think.  I asked her, then how do you know if someone is truly a triple negative, but she didn't really give me an answer for that.

I'm curious if you know your percentages--does it fit with her theory????

Oh, this makes me so cross. There have been at least 2 scandals I can think of in Canada, where pathology was tested incorrectly. It happened most seriously in Newfoundland, where there were thousands of women affected, mostly being told they were ER- when they were actually ER+, and then not being given hormones. People die over this stuff.

I don't know the implications of being triple positive as opposed to only HER2+, all I can think is it does give you more weapons to fight with (Hormones) which I imagine would be a good thing?? 

I agree with Kerry - pathology is not the place to be making mistakes - grrrr....  That's great that you will have new weapons in the arsenal (Tamoxifen and/or AI's), though!   I never really see anything about being PR+ or what else you may be able to use because of it?

I was told that if one is PR+, anti hormones are still perscribed. So, your treatment wouldn't change.

A biopsy on the surgical matter always trumps the teeny tiny shreds they pull on a core needle, etc., biopsy.  That is often a reason for a change in receptor status and isn't all that uncommon.