Infiltrating Duct carcinoma
I have a question that my mother was diagnosed with breast cancer 3 years back T1N1M0, IDC, ER and PR Neg, Her 2 Neu Score1.She had Radical Mastectomy and given 6 cyles of chemo. Tumer messure 1.3X1.4X1CM.
Frozen Read: Invasive malignant Lesion= Nearest margin ( Deeper)shows tumour very close to inked surface. The adjacent breast shows focal areas of in situ ductal carcinoma componenet, adenosis,eithlial hyperplasia and microcalcification.
She used to have Tamoxifen last one year.After the chemo over 9 moths later she had metastasis to lung and she died within three week. Can you please tell what was wrong with the treatment. No radiation was given prior or after the mastectomy. Doctor said chemo doesnt work. Please suggest the right advice. Thanks
Comments
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Dear Space dmt, I am not expert but the doctor where I live do the chest x ray and ct scans ect before they do surgery. The make sure u are not stage 4 before they do surgery. If the cancer has already spread they treat u with chemo. The reason is to keep u strong and there is no point in removing the tumor in the breast if it has already spread. Oncologist might do things different at different hospitals. Icey
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First, spacebmt, I want to say that my heart goes out to you for your loss. There are no words that can adequate express the feeling of losing a mom, especially to such a vicious disease.
Wow, icey, my breast surgeon didn't do any scans prior to surgery and mentioned to me that they could not stage the cancer until after it was removed and biopsied. Even so, I would never have allowed for "it" to remain inside of me, regardless of the stage.
My medical oncologist sends his patients for scans (in my case, head, chest, abdomen, pelvis and bone) prior to starting chemo, but not necessarily prior to recommending the chemo regime. If the scans come back with something after chemo has started, they adjust then.
In my case, I was IDC, 2.7 cm, ER+/PR-;HER-, clear margins and no node involvement. But I had uterine cancer when I was 27, so he requested a full boat set of scans. I got the impression he might not have requested so many had my cancer history been different and just going off the post-tumor removal pathology report.
I have no idea what, if any, scans or imaging my radiation oncologist will request/require, since I won't start with any radiation (I'm to get 33 hits) until after the chemo is complete.
I do now have to go back for another needle core biopsy of 2 suspicious nodes (found in the CT scans pre-chemo), and an MRI to get a better look at 2 liver lesions (also found in the CT scans pre-chemo).
Every bit of treatment or protocol depends so much on the unique situation of each patient and on the standard of procedure that the patient's various doctors normally use.
It's almost impossible to say, "X-step should have been done first, or Y-step is always used."
That's why, spacebmt, unfortunately, your question needs to be directed to a highly qualified person or group (such as Sloan Kettering perhaps?) who can review all the information and images and reports.
Also, another thing to keep in mind is that virtually every year, doctors and health care professionals working in this field learn more and more and more about the disease, and, fortunately for us, use that information going forward to adjust treatments as necessary.
What might have been an acceptable protocol 2 or 3 years ago, may well be done differently now. But that wouldn't automatically imply that the doctors provided less-than-standard care.
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I am so sorry you lost your mother to this wicked disease :< Like Michele, I didn't get any scans until after my mastectomy and had the full pathology back. That's when I found out it had spread to my lungs. I have found with this disease there are no easy answers. I agree that you should take this history to a qualified specialist for review, and find out what the protocols are and why your mom did not get any scans. I was stage IV from the start, so I am not sure how often they scan earlier stages if there are no symptoms to be checked? I am sending you warm hugs and hope you get the answers you need.
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Hi
thanks for sharing me your experience in this issue.I pray God to be with you always.Let,s hope for good. Thanks.
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hi, sorry for your(spacebmt) valuable loss. i have a question to you. did you ask yor doc about radiation after chemotherapy? or the patient was unable to bear radiation that time? (i m not expert) my mom received chemo +radiation + 5 years tamoxifen after total mastectomy of right breast despite no nodal involvement (t3n0m0 at jan2000). anyway good luck to you. thanks for your nice sharing.
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hi all, give me a suggestion from your knowledge and experience. my mom(age 50) is a 10 years survivor of breast cancer. T3N0M0 at jan 2000. received chemo (CMF) + radiation+ 5 years tamoxifen successfully. no symptoms of recurrence yet by the grace of almighty. but recently she can not tolerate any medication.(say amoxicilin for infection or pain killer or others). she is becoming weak day by day. her liver function, ultrasonogram of abdomen, chest x-ray, ecg, CT scan brain are ok. doc diagnosed her sinusitis as she often claims for headache but she fails to receive medicines for sinusitis. she has less interest even in food intake. she claims for acidity to take food. do u have any good suggestion for my mom? any informative website for this or any person having similar experience? i will b grateful to u. good luck
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Hi Farooqbd...I'm sorry to hear that your mom is not wanting to eat and that various medications are not agreeing with her. I'm certainly no doctor...but it sounds like she might be depressed. Could this be a possibility? I wonder if she was prescribed medication for depression if some of her symptoms might change and her appetite return?
You say that she has failed to receive medicine for sinusitis. Does this mean that the Dr refuses to prescribe something or that she was given something and she doesn't want to take it? I know that sinusitis can cause terrible head aches.
It also sounds like your mom is having re-flux issues (digestive juices pushing back up the esophogus). Antacids of course can help there and avoiding spicy foods...but that is easier said than done isn't it?
I hope your mom gets well soon and that you get some good advice here or somewhere else. Your mom is lucky to have you as her daughter. Good luck to you.
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thanks linda for your reply. you are right. naturally depression is one problem of my mom. her major problem is doc prescribes medicines but she can not tolerate any medicines. she feels irritation or weakness if she take medicine (antibiotics or others). i dont know, is there any chances for immunity degradation after long time survivor(10 years+). seeking more suggestions regarding this. good luck
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