Is it politically motivated?
Comments
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I'm glad we're on the same page 2tzus -- now, we just need to stop these guidelines. I haven't a clue how (oops, means cake and ice cream time) -- contact congressmen/women? I think/hope with all the negative media attention the guidelines are getting I can't imagine them being adopted.
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Someone posted recently on another thread that the federal gov't is now distancing itself from the guidelines. But as someone suggested, is it just "hot air"?
Edited to add: Or are, gasp, they listening!!! Let's hope.
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Yes, the Federal Government has distanced themselves from this panel's recommendations and clearly stated that the panel's recommendations are not those of the US Government. The US Government is recommending no change in screening procedures. And, for the first time on the mass media, I heard last night that "there are questions about the motivations of this panel." That was my question two days ago.
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ADK...The federal government is lying because this panel IS part of the US government! If they want this panel to change their recommendations then they would tell them to do so! Any "Study" can say anything you want it to say, you just need to pick and choose the "evidence" you want to use from the study to get what you want done.
Don't believe me? Here is their website and then tell me if you think it is the government?
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I went to the website (http://www.ahrq.gov/CLINIC/uspstfix.htm) and read that the Preventive Services Task Force is:
"An independent panel of experts in primary care and prevention that systematically
reviews the evidence of effectiveness and develops recommendations for clinical
preventive services."So, no, I don't think the Task Force is "part of the government."
Another link on the left of that website says "Clinical Practice Guidelines." It takes you to:
a National Guideline Clearinghouse for guidelines submitted by professional organizations, like the American College of Obstetrics and Gynecology (ACOG), American College of Radiology (ACR), American Society of Breast Surgeons, etc. These particular organizations have already spoken out against the Task Force recommendations, and I am quite sure they will continue to post guidelines counter to the Task Force crap on this other "government" website.
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AHRQ sits over the Preventive Task Force in the hierarchy. No way to get around that if you follow the trail. Surprised MSM hasn't seized on this. Here are two good links which demonstrate this on AHRQ:
http://www.ahrq.gov/about/whatis.htm
HHS Sebelius and the WH is indeed trying to distant themselves from this Task Force's recent publication. But behind the scenes there are undoubtely sharp words to ahrq that this was even approved for production. Or, if you're a conspiracy nut, are there? Is there a bigger picture some are not privy too. Drawing from my own life experience, timing is everything, and nothing is unplanned.
Ahrq had the ultimate decision making power whether to release this task force's recommendations now, or (shocking) send it out for peer review including to oncologists and breast surgeons.
Oops,
Tender
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Tender, the guidelines were published in Annals of Internal Medicine. That means they were peer-reviewed. Of course, I don't know if there were oncologists, breast surgeons or breast imaging specialists among the peer-reviewers -- that remains anonymous.
As a co-author myself on a large randomized controlled clinical trial (evaluating the safety of exogenous estrogens in lupus -- oral contraceptives in premenopausal women and HRT in postmenopausal women -- in terms of whether they caused lupus flare) that was published in both Annals and in New England Journal of Medicine, I am 100% certain that the release date of these guidelines was entirely due to the Annals editorial process. Three papers from the Task Force were published on Monday Nov 16 in the current issue of Annals:
1) a summary of 6 computer models of the risks and benefits of mammography screening
2) a review of studies of the effectiveness of mammography screening
3) "guidelines" based on the above 2 papers
Also, an editorial discussing all 3 papers was published.
I disagree with the authors' interpretation and conclusions of all 3 papers, but I don't think AHRQ can choose to dictate the interpretation and conclusions of authors of scientific papers, or refuse to allow publication, or control the date of release of peer-reviewed publications in a peer-reviewed journal like Annals of Internal Medicine. It gets put out into the medical literature for review, debate and refutation by others.
The process of peer-review of 3 papers takes months. I imagine these papers were submitted in January, in March the authors got the reviewers' comments, in April or May (if working really fast, with great communication among multiple authors) they submitted revised manuscripts addressing the reviewers' comments, then there may have been a second round of revisions, finally the papers were accepted, the multiple authors had to sign copyright agreement forms and Conflict of Interest disclosure forms, then proofs were made available, proof-read by the authors and approved, then the papers went into the publication queue -- under "embargo" so that no word could be released until the publication date. Somewhere in there, after acceptance of the 3 papers, the journal invited an editorial by an unrelated author. The time-line involved writing, peer-reviewing, editing and proofing of the editorial as well.
[FYI, our papers on lupus and estrogen reported results of a study sponsored by an NIH Grant and the Office of Research on Women's Health -- also agencies of the Department of Health and Human Services, part of the executive branch of "the government." We sent NIH/ORWH a copy of the corrected galley proofs, and the planned press release (released by journals to the press on the evening before publication), but the NIH/ORWH did not and could not "control" what was said and whether or when it was published. By contrast, drug companies do control what is submitted for publication by their researchers.]
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It was the original two studies on which the Task Force reached their conclusions which were peer-reviewed in the Annals of Internal Medicine, not the subsequent Guidelines themselves written by the Task Force. Curious too on journal selection for peer review of the original studies. Why the Annals of Medicine for mammogram guidelines rather than the re-known Journal of American Society of Clinical Onocolgy? Perhaps because the inital study data would have been analyzed differently by expert peer oncologists?
"The USPSTF guidelines were updated using evidence from two studies commissioned by the task force and reported in the same issue of the Annals of Internal Medicine. One study, funded by the Agency for Healthcare Research and Quality, is an updated systematic review of screening mammography randomized, controlled trials (Ann. Intern. Med. 2009;151:727-37). It concludes that mammography screening reduces breast cancer mortality by 15% for women aged 39-69 years, and that both false-positive results and additional imaging are common. Among the studies reviewed, "rates of overdiagnosis vary from less than 1% to 30%, with most from 1% to 10%," noted investigator Dr. Heidi Nelson of Oregon Health and Science University, Portland.
The other study, by the Cancer Intervention and Surveillance Modeling Network (CISNET) that was funded by the National Cancer Institute, used estimates of screening outcomes for a range of screening strategies at different frequencies and ages of initiation and cessation (Ann. Intern. Med. 2009;151:738-47). This study concluded that "biennial intervals are more efficient and provide a better balance of benefits and harms than annual intervals." Three potential screening harms were examined: false-positive mammograms, unnecessary biopsies, and overdiagnosis. "
But, the American Cancer Society, which has been at the center of a recent "media firestorm" over rumors of a similar softening on breast and prostate cancer screening, was quick to distance itself from the new USPSTF recommendation.
"The American Cancer Society continues to recommend annual screening using mammography and clinical breast examination for all women beginning at age 40," ACS Chief Medical Officer Otis W. Brawley said in a written statement. "Our experts make this recommendation having reviewed virtually all the same data reviewed by the USPSTF, but also additional data that the USPSTF did not consider. When recommendations are based on judgments about the balance of risks and benefits, reasonable experts can look at the same data and reach different conclusions."
http://www.oncologystat.com (regrettably, password protected site,i.e.,must register)
Here too:
Retraction urged
"James H. Thrall of the American College of Radiology, which condemned the guidelines, praised Sebelius's statement but called on the secretary to order the task force to rescind its recommendations "to avoid confusion as health-care reform moves forward."
Thrall also urged Sebelius to make sure the panel included "experts from the areas on which they will be advising lawmakers and submit their recommendations for comment and review to outside stakeholders in similar fashion to rules enacted by the Centers for Medicare and Medicaid Services. A more inclusive process can only benefit Americans as we seek to improve our health care system."
Sebelius pointed out in the CNN interview that the task force was appointed by the Bush administration. Calonge said the members were selected independently with no political interference"
www.washingtonpost.com on 11-18-09
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AnneNYC...Who pays these people who are part of the "Independent panel?" Oh, the government.
And where are the "experts" about breast cancer on this panel? I don't see one Oncologist or Breast Surgeon present on the list of experts.
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I agree Madalyn. I mainly highlighted Dr. Thrall's words because I read them this morning and found the calling for oncologists, breast surgeons and yes, even radiologists to the table to be an issue I agreed with.
Radiologists must have a very difficult time seeing through glass prisms on this issue.
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Colette, I totally agree with you about the lack of breast cancer experts on this panel. In fact, I've been posting the panel members' names, highlighting their specialities in bold, as a "Hall of Shame" two or three times here on BCO in the last few days. No disagreement here.
I've been trying to look up the reimbursement rate for Task Force members. When I get an answer, I'll post it.
But they are not employees of the AHRQ (an agency of the DHSS, a cabinet-level department). Whatever they are paid, it is likely an honorarium or per-diem-reimbursement type of payment. Based on what I know about academic doctors (who I've worked for for 25 years) serving on FDA panels, or other policy panels, I would guess it's $300 for a day when they've actually traveled to Bethesda or DC for a meeting. I'd guess $1,500 a year -- but maybe as much as $10,000 a year. But I'll keep trying to find out.
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Hi Tender,
I would have thought that the guidelines were peer-reviewed as well, as they are published in the same issue of Annals, as a group with the other two papers, under the "peer-reviewed" section of the Table of Contents.
U.S. Preventive Services Task Force. Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement. Ann Intern Med November 17, 2009 151:716-726.
But perhaps not.
I totally agree that I think it's crazy that these primary care types were charged with issuing these guidelines -- and because they're primary care types, "Annals" is where these types choose to publish.
I swear, I wonder if Susan Love was a peer-reviewer! Seeing as she's so vigorously supporting the new guidelines!
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For what it's worth, this is what's published in Annals of Internal Medicine at the end of the "Guidelines" paper:
Disclaimer: Recommendations made by the USPSTF are independent of the U.S. government. They should not be construed as an official position of the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services.
Financial Support: The USPSTF is an independent, voluntary body. The U.S. Congress mandates that the Agency for Healthcare Research and Quality support the operations of the USPSTF.
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Hi Ann,
It is odd the way the Taskforce is under AHRQ, yet publishes the Guidelines in the Annals of Internal Medicine. Thank you for looking into reimbursement of the sitting panal: I'm particularly curious about the Chairman's relationship with any health insurance company and whether this is a conflict of interest. It would seem difficult to wear two different hats, especially when health insurers have the bottom line of their business to see meet.
If the AHRQ, as per it's mission statements of best evidence clarification, continues on with these Taskforce Guidelines, why not submit them for publication in the Journal of the National Institutes of Health. But perhaps that's too blatant a connection? Like all others, I firmly stand on transparency with this government issue (NIH grant supported, Task Force oversight and Per Diem's etc) and the far reaching effect of production of independent mammogram guidelines.
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I did read (although I can't seem to locate it just now) that the panel members are voluntary, and I'm quite sure, as AnnNY has stated, that they are paid a per diem for meetings attended. That is the way most voluntary task force panels are re-imbursed (at least north of the border).
Edited to add: posting at the same time as Ann
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Thank you for finding that disclaimer, Ann - it can't get any clearer than that.
Disclaimer: Recommendations made by the USPSTF are independent of the U.S. government. They should not be construed as an official position of the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services.
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just wanted to chime in her - hope no one minds - I too am outraged by these new guidelines and think it is political - here is my question? All the politics aside when push comes to shove unless Mr. Obama is going to tell his 45 year old wife to let her mammos go for 5 more years than the guidelines need to just be thrown away - "good for the goose is good for the gander" If they are willing to apply to their personal life then fine if not then the guidelines should not have ever even been made public - just my opinion
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Not to push too far here, but as any legal scholar will tell you, Disclaimers are only as good as the people writing them and their circumstances.
AHRQ Mission
The Agency for Healthcare Research and Quality's (AHRQ) mission is to improve the quality, safety, efficiency, and effectiveness of health care for all Americans. Information from AHRQ's research helps people make more informed decisions and improve the quality of health care services. AHRQ was formerly known as the Agency for Health Care Policy and Research.Disclaimer: Recommendations made by the USPSTF are independent. They should not be construed as an official position of the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services
I don't see how there's not a conflict of interest here in spite of the AHRQ disclaimer. AHRQ is looking for efficient, informed quidelines, and USPSTF provided them. Curiously, the USPSTF mammogram guidelines are more "limiting" in their effect: limiting in medical provision to 50 year olds and then every other year, limiting in cost by reduced mammograms to society (but) limiting in safety to the 3% of patients whose missed cancers are considered acceptable from a societal (not individual view, or are they?). Except for the safety issue surrounding the 3% missed, this in line with AHRQ's mission of efficiency: ef·fi·cient: productive of desired effects; especially : productive without waste (Sorry 3%).
http://www.merriam-webster.com/dictionary/efficient
Perhaps the AHRQ might recognized a slight forked tongue situation here, and completely separate the USPSTF from their agency as well as incorporate physicians of interests such as breast surgeons, radiologists and oncologists in their discussion panel on mammograms. This would at least give at first blush the appearance of a more independent panal. Breast associations/foundations might be willing to pay the per diems.
I'm hoping this recent windstorm on mammogram guidelines controversy might allow recognition of some of these finer points, with the goal of real transparency on both governments and panels, and with ALL American women and mens safety in mind.
Tender
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I agree these guidelines need to be tossed aside. The reason why I asked if it was political is that I saw it as an attempt to derail health care reform and by the reaction, I would say I may have been correct. What is really bothering me is all the comments aimed at the president - I don't think we have even heard anything from him on this issue yet (correct me if I am wrong) and by their own disclaimer, the panel that issued these recommendations are not reflective of the US Government. Personally, I think this panel needs to be disbanded.
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The task force has decided that 3% isn't enough lives to justify the "risk" (and by risk, they of course mean cost) of annual screening mammograms. They say that the anecdotal/personal stories are of course compelling, but not enough to impact the public policy.
Frankly, I would have an easier time discussing this if they would just state that clearly (as one task force member did on a radio interview I heard today.) The hiding behind the "risk of radiation" which is ludicrous, and even worse, the "stress of the false positive" is insulting to my intelligence, and quite frankly hurts my feelings. Tell me you are OK with me dying from undetected cancer because it's not cost effective to screen me. Don't tell me you're OK with it to prevent women from stress.
The part that has caused me to have a stomach ache for the last few days is the statement that many women in the 40-49 age group have aggressive cancers that don't respond to treatment. In other words, mammography doesn't save their lives, because while it may identify the cancer, the treatment isn't effective. I heard a task force member say that while yes, the screening mamm did detect the cancer, "the life years gained are not very large" and therefore, it was once again, a "small benefit."
I am still chilled by the lack of emotion on her face as she made that statement.
You know, if the difference in the numbers was larger (ages 50 - 59 = 1300 mamms to save 1 life; ages 40 -49 = 1900 mamms to save 1 life) I think I would have an easier time understanding it. If the age 40 -49 was 5000 mamms to save 1 life, I really think it would be more palatable somehow. 600 just doesn't seem like that much to me.
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The Bush Presidency appointed this panel. It's politically motivated, he's given the insurance companies another break. Damage done, they won't have to pay for mammos any more.
I'm sure Obama had little to no knowledge about it at all until the report....
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Moi, I think Obama needs to take responsibility for and be held accountable for what happens on his watch. This happened on his watch. If he is President and is he has no clue what a task force is up to and the damage they are about to inflcit..he should just quit because he is not doing his job. I am will bet $$ that he was involved in this.... people may love Obama..but the guy is not perfect...he does dumb things and makes mistakes like the rest of the world...people need to realize that and call him on it when it happens. Didn't Obama yell during his campaign that his mother died of cancer and he would take care things?? This week, I am thinking he didn't love his mom very much. Well like people can cause much damage and we shouldn't keep someone in office because they have a nice smile while hurting people.
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Actually, this didn't happen on his watch. He wasn't in office before this year, and this was done how many years ago? Two?
He cannot know everything about everything in government, I think that would probably be impossible. However, I do agree with you that he has to take care of this problem, like, yesterday.
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"The task force doesn't argue that mammograms have saved the lives of many women like Sara Fought. In fact, the task force mentions in its statement that for every 1,000 women in their 40s who receive routine mammograms, two cases of cancer are detected. However, it also notes that 98 women will have "false positives." In other words, the mammogram will pick up something that looks like cancer, but that further testing shows actually is not."
http://www.cnn.com/2009/HEALTH/11/19/mammogram.guidelines.insurance/index.html
I would think that this finding would lead the panel to propose ramping up the efforts to determine how to rule out 'false positives'. Talk about throwing out the baby with the bath water.
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Moi, the announcement did happen on his watch and I think he knew all about it...but guess we can't prove either view of that. You are right, we can agree that he needs to start fixing away.
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Excellent point Pretty In Pink...Mammos are good at finding things...and are still evolving as a screening/diagnostic mechanism...they did throw the baby out with the bath water with the task force announement. And what is scary about it is these are supposed to be smart people that did this....sure does make ya wonder!
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Peppi1, in my opinion a lot of "smart people" in statistical medicine are overly stuck on the idea that nothing can be known in medicine unless it is shown in a huge, prospective randomized controlled trial.
But some smart people in clinical medicine disagree (warning: satire ahead):
http://www.bmj.com/cgi/content/full/327/7429/1459
********************************************************************
BMJ 2003;327:1459-1461 (20 December), doi:10.1136/bmj.327.7429.1459
Hazardous journey
Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials
Gordon C S Smith, professor1, Jill P Pell, consultant2
1 Department of Obstetrics and Gynaecology, Cambridge University, Cambridge CB2 2QQ, 2 Department of Public Health, Greater Glasgow NHS Board, Glasgow G3 8YU
Abstract
Objectives To determine whether parachutes are effective inpreventing major trauma related to gravitational challenge.
Design Systematic review of randomised controlled trials.
Data sources: Medline, Web of Science, Embase, and the CochraneLibrary databases; appropriate internet sites and citation lists.
Study selection: Studies showing the effects of using a parachuteduring free fall.
Main outcome measure Death or major trauma, defined as an injuryseverity score > 15.
Results We were unable to identify any randomised controlledtrials of parachute intervention.
Conclusions As with many interventions intended to prevent illhealth, the effectiveness of parachutes has not been subjectedto rigorous evaluation by using randomised controlled trials.Advocates of evidence based medicine have criticised the adoptionof interventions evaluated by using only observational data.We think that everyone might benefit if the most radical protagonistsof evidence based medicine organised and participated in a doubleblind, randomised, placebo controlled, crossover trial of theparachute.
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I'm glad Ann you posted that link here as well...........you go girl!
Edited to add - the link brought me to a sign-in page so the entire text wasn't visible. Could you copy and paste it here Ann?
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I edited my post above, swimangel ! Glad you liked the abstract !
In my opinion, that is the heart of the problem with the USPSTF -- an overly rigid adherence to a current fad in academic medicine...
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Moi...keep in mind I never voted for either Bush, and I didn't vote for BO either because I look at the individual not the party affiliation. BO is acting like we are attacking him personally, as if he is guilty of something.
What I want to know is why this "Task Force" is also suggesting that prostate exams for men should be stopped also and why they are even around making these "Suggestions" that insurances follow...which will be the US government if BO and the congress gets what they want with the government mandated health insurance. I do agree that BO needs to get rid of the task force if he wants to prove that he is more than just hot air.
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