Tykerb and pain medication

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anitach
anitach Member Posts: 191
edited June 2014 in HER2+ (Positive) Breast Cancer

My onc. is recommending me to join a study for Tykerb and I was just reading up on it a little bit. I knew about the side effects of diarrhea, rash, fatigue but I didn't know that Tykerb could cause liver damage.

Anyone that is on Tykerb... are you limited in what kind or how much pain medication you can take because of the Tykerb?

As always, thanks for any info you can offer!

Anita

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  • chainsawz
    chainsawz Member Posts: 3,473
    edited October 2009

    I'm taking tykerb (1250mg) along with my herceptin and side effects haven't been too bad.  Nothing compared to TCH!!  I did have a problem with the diarrhea the first few weeks - I took immodium and that helped control it for me.  Now the problem seems to be better.  As for pain meds, the pharmacy that dispenses tykerb to you has a nurse on call and you can ask any questions like this to be sure.  I ran all my meds by this nurse and they were all safe, so it hasn't limited any of my pain meds.  I do have to be careful not to eat grapefruit.  Best of luck to you!!  lisa

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  • tapmrv
    tapmrv Member Posts: 66
    edited October 2009

    Just started Tykerb on Friday night.  No problems so far.

    Teresa

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  • marieibrahim
    marieibrahim Member Posts: 188
    edited October 2009
    i have been taking tykerb for about 8 months now for MBC ,I HAD NO BIG PROBLEMS SO FAR BUT OCCASIONAL  DIARRHEA,I THINK MOST REPORTED SIDE EFFECTS HAPPENED WHEN TYKERB IS TAKEN WITH XELODA,BUT YOU SHOULD MONITORE YOUR LIVER ENZYMES ,AND IF YOUR ARE TAKING 5 BILLS TRY TO AVOID GRAPPEFRUIT.BEST WISHES
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  • 3katz
    3katz Member Posts: 1,264
    edited October 2009

    Been on Tykerb (1250 mg/day) with Herceptin nearly a year. Very tolerable. The worst side effect was the Tykerb Trots and immodium really helps. My onc said nothing about interaction of pain killers. Actually, the oxycodone usually counteracts the "trots." Good Luck!

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