Curcumin (Turmeric)

Hi Timothy

I e-mailed Sloan Kettering Integrative Medicne and asked about curcumin interfering with tamoxifen absorption and here is their reply:

Curcumin inhibits CYP3A4 enzyme and, in theory, may interfere with the action of tamoxifen, a substrate of this enzyme. However, these products have not been studied together in a clinical setting and the exact interaction remain unclear.
Since each person's condition is unique, we suggest you seek advice from a medical professional who understands your background. The Integrative Medicine Service also provides consultation on the proper use of supplements. You can call 646 888-0800 for more information.

Integrative Medicine Service
Memorial Sloan-Kettering Cancer Center

I see my medical oncologist at U of Penn on Tuesday and will ask his opinion about Curcumin and Tamoxifen.

Roseann- the brand I brought was Terry Naturally "Curamin" - it does have a herb in it called boswellia which is also in Move Free Flex Advance (a glucosamine product I take). For my joint paint I always start out with 1 tablet of what ever and tried that for a couple of weeks, if it seems to work I stop there if not I bump up. Curamin is also asaid to be anticancer.

Here is some more information I found on this brand

Curamin is an all-natural dietary supplement. It is a powerful formulation of: Curcumin, curcuminoids, dl phenylananine, Boswellia and Nattokinase. Curamin enhances the body's natural defense mechanisms for the relief of inflammation and pain due to overuse.* 90% of satisfied customers experience relief in 45 minutes Ask for Curamin at your local health food store or independent pharmacy that's all it said, hope this helps! and:Serving Size 2 Capsules

Proprietary EP612 Complex .... 1005mg (Curcumin, Curcuminoid, Boswellia, DLPA(dl-phenylalanine), Nattokinase)

Other Ingredients: Magnesium Stearate, Gelatin Capsules

Does not contain any preservatives, chemicals or allergens except for the food grade ingredients listed.