2 Year Hera Results????

There was a St. Gallen conference in Switzerland in March of this year (don't remember the exact date). I browsed through the abstracts at that time and it was said that the results would be made public when ready, that is not before 2011.

:-(

-Helena.

I'm assuming that no news is no news - they must be monitoring the results and if the interim results were showing anything that would change treatment recomendations like an advantage for the extra year of Herceptin, they would have reported it. They reported interim results of the other  Herceptin trials and the 1 year of Herceptin for this trial with only a few years of follow-up because they showed that Herceptin was having a significant benefit.

It is frustrating to me that the Herceptin studies all released results in 2005 or 2006 when they had 2 to 4 years of follow-up and once they got their FDA approvals for the Herceptin based-therapies, they haven't put out anything additional. I'd like to know what recurrence and survival stats are looking like for 5 or more years after treatment. It doesn't look like any of them are going to release more results until they have 10 year results or something. 

:-{ 

Can someone explain the difference between 15 and 16 it looks like the same slide  but different percentages on DFS?

Thanks for the update on the 4 year Hero trial.  I THINK it concludes that there continues to be risk of reccurance after the third year.  Would it be possible for someone to summarize the results in very general terms?  Does Herceptin continue to help those of us who took it for one year?  Does risk decline significantly after the third year?

Jo Anne

Hello 

So in my opinion, as You see on the 6th slide, the DFS curve is getting more and more horizontal after about 30. month of follow up. The conclusion is that the biggest risk of recurrence is in the first 30 months after surgery and after that time (after these 30 months) the risk still exists but is much smaller and is still getting smaller over time. 

Sylwiamolik,

You raise a point that I have often wondered about.  Because I am also ER/PR negative, I have also looked at the survival rates for triple negatives.  If, as you stated, the risk ratio is the same for Her2positive as for Her2negative after 3-4 years, the survival data for triple negatives becomes important in my case and  ER/PR positive data becomes important for ER/PR positive women.

For ER/PR-, HER2+ women, it implies that at 5 years our risk factor for recurrence is down close to zero and after 8 years, we can be considered "cured"  (this is based on readings I have done on trip negative disease).

 I am at 30 months post chemo, 33 months post surgery and guess I can start to breathe a bit easier as far as recurrence risk.