Chemo Help Needed (Insomnia, Mouth Sores and Neuropathy)...

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My mom is getting weekly Taxol (and daily Sutent as part of a clinical trial) for 12 weeks, to be followed by 15 weeks of weekly Adriomycin and daily oral dosage Cytoxin. She is currently taking temazepam (15 mg) for insomnia to help her as she goes through neo-adjuvant chemotherapy.  She is taking 2 pills per night (30 mg) but it is not helping her sleep.  Can anyone recommend a different prescription for sleeping pills that are more effective?  Also, she is beginning to get mouth sores (she's had two weekly treatments of Taxol/Sutent so far), does anyone have any recommendations to help?  I've already read of sucking on ice chips during the chemo infusion (we'll try that at tomorrow's treatment), she has been using Biotene toothpaste and mouthwash since she started chemo and I'm going to get the Maalox/liquid Benadryl and make the mouth rinse cocktail I read about on this site and see if that helps.  Any other recommendations?Also, she's experiencing some tingling in her feet from the Taxol (neuropathy).  I've read glucosamine can help.  Any other suggestions?  Thanks for any help or suggestions you can offer!Dx: 4/09; 5-6 cm, Stage IIIB, Grade 3, ER-/PR-/HER2- (Triple Negative) 

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  • LolaHank
    LolaHank Member Posts: 28
    edited June 2009

    Mouth sores are awful.  Try a rinse by the name of Oxyfresh, I got it at my dentist.  Or my oncologist said to get glutamine (powder you mix with oj) at the health food store. They were terrible at first, but after the 3rd chemo I didn't get them again. I didn't have any tingling.  Hope this helps. Hang in there! Sarah

  • idaho
    idaho Member Posts: 1,187
    edited June 2009

    I have heard that you can have a dentist laser mouth sores and then they don't hurt so bad and heal faster- call around and ask.  good luck - Tami

  • LRM216
    LRM216 Member Posts: 2,115
    edited June 2009

    I was given "Magic Mouthwash" by my onc and the druggist makes it out of Maalox, benedryl and lidocaine.  It is magnificent.  Please ask for it.

    Linda

  • taj72
    taj72 Member Posts: 50
    edited June 2009

    Thanks, ladies!  My mom had a chemo round today and they gave her a Rx for Magic Mouthwash. She had been taking Biotene but the nurse said to stop taking it because it was too harsh on her mouth.  Who knew?  I got the Biotene recommendation from the boards, but it doesn't work for everyone I guess. Thanks for everyone taking the time to respond and share your recommendations though!

  • dlb823
    dlb823 Member Posts: 9,430
    edited June 2009

    taj ~  Has your Mom tried B6 (a vitamin supplement available in any health food store) for the neuropathy?  It worked great for me when I was on Taxotere.  It's reasonably priced, and has no side effects.  Definitely worth a try...   Deanna

  • NatureGrrl
    NatureGrrl Member Posts: 1,367
    edited June 2009

    The Mary's Magic Mouthwash has worked wonders for me (and for my mom when she needed it).  The ice chips are given to me when they're actually injecting the adriamycin (dose-dense) but I haven't seen it used for other chemos -- but that doesn't mean it doesn't help. I haven't gotten many mouth sores, just thrush, but the few I get are wiped out quickly by the MMM so hopefully that'll help your mom as well.

    I was told to stay away from any alcohol-based mouthwash because it can kill the beneficial organisms in your mouth as well as the "bad" ones, and when your immune system is knocked down it needs all the help it can get.  (I know Biotene is alcohol-free, just talking about other mouthwashes)  A small amount of baking soda mixed with a glass of water a couple of times a day (rinse and spit) is supposed to help prevent (& treat) mouth sores.  I keep forgetting to try that one but maybe I will next week.  Trush is bad enough, but the mouth sores are really uncomfortable!

    When your mom starts on the adriamycin, you might want to check with your doctor before she tries any OTC meds, vitamins, etc.  There are several things that you're supposed to stay away from (including any vitamin oils, like flax seed oil, fish oil, vitamin E, etc., aspirin and aspirn-related products, and alcohol and caffiene. What, no coffee?) :) while on adiramycin that are normally harmless but can interfere with the chemo or cause other problems, so it's worth checking.  I don't do any vitamins, herbals, etc., without asking my dr. first.  (I'm going through this chemo and after all the fatigue, etc., I sure don't want to do anything that might interfere with how it works!)

    I can't recommend sleep meds because I don't use them -- check with your dr. -- everyone reacts so differently to those things so she may have to try a few to find the right one.  I rarely take atavan (mostly for anxiety when I do take it) and it tends to knock me out.   If your mom is stressed out she might talk to her dr. about that and see if an anti-anxiety med doesn't help; I took xanex for 6 weeks several years ago when I was going through a difficult time and although it wasn't a sleep med, it did help me relax more so that I did sleep better.

    I don't know much about neuropathy but since I'll be on taxol after I'm done with the A/C, you can bet I'll be looking into options!  That's one of the side effects I really, really don't want. So I'm checking out what everyone says about that.

    Good luck to your mom and to you.  In addition to my own cancer, I'm helping my mom with hers, so I know the role you're playing is a big one.  Don't forget to take care of yourself!

  • ddlatt
    ddlatt Member Posts: 448
    edited June 2009

    i had tingling and numbness (neuropathy) in the feet and severe tingling/itching in the hands when i was on taxol. my only relief was atarax (hydroxyzine), which saved my life. my hands itching just about drove me insane. i also took B Complex every day and 20g of L-Glutamine in my smoothie every morning, both of which supposedly prevent or reduce the neuropathy. i had very bad leg bone pain from the taxol, and finally went through several kinds of pain meds until i found one that kept me from feeling the pain -- oxycodone 5mg, and i took 1/2 a pill every six hours the day of chemo and the following three days. this helped with the terrible soreness from the neulasta shot also. you're a good daughter!

  • taj72
    taj72 Member Posts: 50
    edited June 2009

    Thanks for all the suggestions.  I have passed them on to my mom.  

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