atrophic vaginitis and estrogen cream

BRCASurvivor
BRCASurvivor Member Posts: 2

     I am wondering whether or not any survivors who are estrogen and progesterone + have done any research or are currently using estrogen cream? I am a single 45 year old woman who has no children. My former boyfriend and I are no longer together. It is impossible for me to have intercourse due to pain and I have had difficulty with UTIs.

     My oncologist denied my request for estrogen cream. My gyn said he would write for estrogen cream, if I was able to locate an oncologist who would approve it. He further stated he would write for whatever type of cream the oncologist recommended. (I broke down in tears in his office.)

     I have gotten a second opinion and this oncologist said she would approve estrogen cream, since lubricants have not been effective and quality of life is an issue. However, she said she does not know a lot about estrogen creams and would approve whatever the gyn felt was best. I seem to be caught in a circle and am trying to do my own research.

     Does anyone have an oncologist prescribing estrogen cream for them? What is best for a person with my cancer hx?

     I truly appreciate any feedback you are able to share.

      Thanks!

Comments

  • Katalin
    Katalin Member Posts: 230
    edited April 2009

    It's a little like being caught in a game of monkey-in-the-middle....My experience is quite similar to yours.  Except it went like this:  I complained to my GP.  She said talk to your gyno.  The gyno said talk to the oncologist.  The oncologist said:  only if your gyno approves.  Finally my gyno wrote me a script for vagifem tablets, 25iu.  I never quite felt good about it though, it just seems so insane to take tamoxifen or AIs and take all these dietary precautions to reduce estrogen, and then to add it back into my system?  They say small amounts do pass into the blood system...Anyway, I finally told my oncologist, and she was appalled, and said it was not a good idea.  The gyno then said that she thought I was telling her that the oncologist approved.  All this took maybe 5 months.  In the meantime, I had stopped using it.  Currently, my DBF (dear boyfriend) is putting up with infrequent nookie, (this has been three years!!!) but we are making it work, doing other things Smile I am almost ready to tackle this problem again, by getting a new referral to a gyno who does not just specialize in dealing with pre-cancerous uterine problems.  There has to be something!!!!  I'm NOT comfortable with bio-identicals, because they're still ESTROGEN!!!  It's like saying, "No fructose or sucrose for me!  Just sugar!!!  Lots of it!!"

    Looking forward to other posters.... 

    Good luck! 

  • otter
    otter Member Posts: 6,099
    edited April 2009

    This topic is wildly controversial.  I know there are oncos who will "allow" their patients to use vaginal estrogen, when it becomes a quality-of-life issue.  You've gotta do what you've gotta do.

    OTOH, I think there is a difference in risk, depending on which type of estrogen-blocking drug we're on.  I read some reports late last year that said women on aromatase inhibitors should not use vaginal estrogen, because the whole purpose of the AI is to eliminate even the tiniest amount of estrogen a post-menopausal woman might be making and have in her bloodstream.

    Vaginal estrogens supposedly are not absorbed systemically, but again from what I've read, that's not entirely true. They can be absorbed in very small amounts, which ordinarily wouldn't be significant ... but it is, when we're on an AI and that small amount is greater than what we would have otherwise.  Also, vaginal estrogens are more likely to be absorbed when they're first being used.  The vaginal walls are thinner and more easily traumatized; so the estrogen can be taken in through the walls and get into the bloodstream.  Once the walls thicken up, that's (supposedly) not as likely to occur.

    Over in the "Moving Beyond Cancer" forum, there is a thread pinned to the top of the list that has a title, "I want my MOJO back" (or something like that).  Check that thread for all sorts of suggestions about solutions to the problem.

    otter 

  • NatsFan
    NatsFan Member Posts: 3,745
    edited April 2009

    I'm ER/PR+ and on AIs and had the same problem.  I had gotten to the point where intercourse was simply out of the question because of the pain and bleeding.  Lubricants were not doing the job at all. I talked with my gyn and my onc.  While both agreed that I shouldn't use Estrace for the long term, they agreed to a very short term use of Estrace - 3-4 weeks max, 2-3 times a week, and at less than half the normal dose.  My gyn felt that a short course of treatment might just be enough to plump up the tissue to the point where the Replens-type lubricants could take over.  As Otter says, it's a risk, but it's also a quality of life issue. 

    That short course of Estrace worked wonders for me.  That was in February, and after a few weeks of using Estrace, things were still a bit painful, but much better.  A few more weeks and regular use of Replens once I stopped the Estrace did the trick.  Things are fine now as long as I use Replens now and then, and a KY type gel.  

    My onc said that if the Estrace had not done the job, he would approve a Femring or eString and monitor my estrogen levels, but fortunately my gyn was right and the short dose of Estrace did it.  That may not work for everyone, but I was willing to take a short term risk for the possibility of a long-term payoff. 

    I also second Otter's recommendation of checking out the Mojo thread.  I tend to be too shy to bring up stuff like that with doctors, but reading that thread made me realize that I was not alone, and I was right to be angry about having my sex life taken away from me, and I had a right to try to get it back.  It really allowed me to have an open frank discussion with both my onc and my gyn.

    Good luck!

  • BRCASurvivor
    BRCASurvivor Member Posts: 2
    edited April 2009

         Thank you for sharing your experiences with me. It took me awhile to figure out how to find my post and see your responses. It so so nice to know that I am not alone in encountering these issues. I was so afraid to even bring up the subject with my doctors since I am single and living in the bible belt region of the US. I was worried they would think I was inappropriately concerned about my sex life and that I should be grateful to have had the cancer treatment I have had.....which of course I am, but not too happy with the side effects!

         I will check out the Mojo thread as well.

         THANKS!

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