Taxotere/Cytoxan

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holligoog
holligoog Member Posts: 75
edited June 2014 in Triple-Negative Breast Cancer

Has anyone with TNBC had sucess with Taxotere/Cytoxan? This has been recommended to me instead of AC-T

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  • TenderIsOurMight
    TenderIsOurMight Member Posts: 4,493
    edited February 2009

    Bump up for holligoog.
     
    TC has often been recommended as an alternative to AC-T as adriamycin is cardiotoxic. You might check with your doctors about these chemotherapy's results (efficacy) in the triple negative state vs the hormone positive state. Perhaps too, one of the tri-negs are more up on this data.
     
    Best to you,
    Tender 
     
     
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  • Melissa1971
    Melissa1971 Member Posts: 60
    edited February 2009

    I live in Louisville, KY and the two onc. I met w/ here both suggested that regimin. I asked alot of questions and consulted w. onc. across the country that are well respected. From what I gathered the TC is potentially just as effective w/ less risk of side effects (the Adriamycin can cause future heart failure, but the risk is very low). But every other onc. I consulted with strongly recomended the dose dense AC/T ( 4 rounds of each) and I consulted w/ top docs in Boston, Philadelphia and Phoenix.  Since I will be getting radiation on the right (site of lumpectomy) not on the left my local onc. agreed that there was less risk to the heart. I was conflicted as to what to do because not only do I want to live a long life but a healthy life as well. The TC may be the better choice but it has only been used for a couple of years and I know w/ TN bc we have one shot to get rid of it for good and I choose to be as aggressive as possible.

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  • tibet
    tibet Member Posts: 545
    edited February 2009

    My Onc (In Switzerland) said that the AC 4 rounds and 12 weekly toxol is better than AC/T 4 rounds each as he said there was a study showing that because over time, you get more toxol in 12 weekly dose than 4 rounds DD.

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  • Vickan
    Vickan Member Posts: 54
    edited March 2009

    Hi Newalex,

    Please contact me on my private mail... looking forward to hear from you.

    X 

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  • guitarGrl
    guitarGrl Member Posts: 697
    edited March 2009

    My doctor gave me the TC combo & I'm feeling (and testing) fine so far, but it has been less than a year that I finished chemo.

    My doctor doesn't use the A anymore - says it's too toxic. If you go to the chemo topic - there's a huge thread from those of us who used that combo.

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  • Melissa1971
    Melissa1971 Member Posts: 60
    edited March 2009

    Although I am getting the dose dense AC/T combo, my onc. was offering me the TC combo but suggested 6 runds vs. the standard 4. I hope I made the right decision in inc. the A. I read the toxicity is more relevant if you have at least 6-8 rounds, so I thought the 4 would be okay.

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  • Patsycan
    Patsycan Member Posts: 9
    edited March 2009

    Here is one that I don't see on here. I am going to have FEC -T 3 rounds of each. What about that one??? The dose dense wsas not an option.

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  • holligoog
    holligoog Member Posts: 75
    edited March 2009

    Did u have 4 or 6 cycles?

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  • WBC
    WBC Member Posts: 3
    edited May 2009

    I had TC. My first onc. rec. TC + A, the second TC. They both consulted with an onc at Hopkins and that onc. (the same one) agreed with both of my opinions - go figure. I went with the onc. I was most confortable with and she was/is cutting edge - said A was too toxic. Now, however, that was in 06 and I am now battling mets. Is that because of no A?  I'm not going down that road, but I know A is still a possibility in my future.

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