Modified Citrus Pectin

This is from MD Anderson website.  I found this after going to a homeopathic doctor.  There is all kinds of wonderful stuff on this.  It has been research for about 35 to 40 years.  Why haven't they put this to use?  Check out all the stuff of the Internet you guys who like to research.  I did take this while I was not in treatment but stop.... My mistake.  You are not suppose to use this while in treatment.  Why I don't remember.  They said it is best to use the kind that dissolves in water.

Flalady

Citrus pectin is contained in the peel and membrane of citrus and other fruits such as apples and plums, but it is most concentrated in citrus fruits. It is widely used in the manufacture of foods, drugs and cosmetics, but is best known as the jelling agent in marmalades and jellies¹.

Ordinary citrus pectin is largely undigested because of its long branched chains of complex sugars (polysaccharides). Modified citrus pectin (MCP) has been changed by acidity and heat so that these polysaccharides are split into smaller, non-branched chains of the simple sugar galactose that are digestible².

Proposed Mechanism of Action
Invasive primary tumors can shed metastatic cells into the blood stream. These cells may subsequently adhere to each other or to normal cells forming clumps (emboli). The tendency of tumor cells to adhere has been correlated with their metastatic potential. Larger emboli (clumps) may be subsequently trapped in capillaries where they begin to grow while smaller emboli and even single cells may develop into larger clumps by adhering to circulating lymphocytes, platelets or cells lining the blood vessels (endothelial cells)³.

This tendency of any cells to interact with and adhere to other cells is thought to be due to certain carbohydrate-binding proteins (lectins) on the cell wall surfaces of both normal and tumor cells^3,4. One of the carbohydrates with which lectins interact is the sugar, galactose which yields the carbohydrate binding proteins known as galectins. When interactions occur between galectins expressed on the surface of metastatic cells and galectin receptors expressed on endothelial cells, the resulting complex (ligand) may then interact with additional cells to yield a growing metastatic colony of cells or contribute to the development of a vascular blood supply for a new tumor^5,6,7.

Modified citrus pectin appears to bind to one of the galectins thus blocking the tumor cells from adhering to each other and to the walls of blood vessels^5,8. Binding to melanoma cells⁷ and human breast carcinoma cells⁶ has been demonstrated in vitro. Inhibition of lung metastasis has been demonstrated in rats^7,5. Inhibition of primary tumor growth, angiogenesis and spontaneous metastasis has been demonstrated in mice⁶. Apoptosis (cell death) has been seen in dexamethasone, melphalan, or doxorubicin resistant multiple myeloma cell lines⁹.

Toxicity and Side Effects
No reports of adverse events have been published in the literature or found in a search of voluntary reports of adverse events to the USDA Center for Food Safety and Applied Nutrition. Although modified citrus pectin is more easily digested than natural citrus pectin, individuals with allergies or sensitivities to citrus may experience stomach discomfort when taking either type of citrus pectin.

As a natural component of food, citrus pectin (even when modified) is considered to be a dietary supplement rather than a drug. As such, it does not require the approval of the Food and Drug Administration (FDA) for marketing. Further information concerning dietary supplement regulations is provided in the FDA Center for Food Safety and Applied Nutrition Overview

Hi trigeek,

Have not seen you in while. How are you doing?

Flalady

Blundin you brave girl to dring this everyday.  Lemon & olive oil aways tell me you are cleaning up the liver and galbladder.  You go Girl!  I may have to try this.

Flalady