CHEMO OR NOT?

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  • kamico3
    kamico3 Member Posts: 90
    edited December 2008

    DoreenF- Thanks for your help! I posted a reply to you today on a different thread but should have put it here. Went for my second opinion today at Dana Farber in Boston and they were unequivocal that they were NOT recommending chemo for me. A big relief (I think!)! So it's on to radiation for me starting next week!

  • nina49
    nina49 Member Posts: 5
    edited January 2009

    Hi, this is my first post, but any advice will be appreciated.  I'm 49 and am tying to decide chemo or not.  1.5cm IDC, grade1-2 (another gray area), node neg, ER/PR+, HER2-.  Oncotype dx score came back 13.  Onc says if it was 11, no chemo, 15 she would recommend chemo.  It is up to me, she said she would not be upset if I pass on the chemo, but if I want it, 4 rounds of TC.  No history of bc in family, I'm healthy otherwise.  This tells me if I read between the lines no chemo, but onc said the docs in her practice had a mock argument on my case and all voted chemo or no, the concensus was chemo.  With my oncotype dx of 13, I have an 8% risk factor.  Chemo drops it by 1/3 and meds by anoter 3, correct?  I may not be able to take tamoxifen due to blood clot risk.  Anyone else in my position?  Thanks in advice Smile

    nina49

  • rdrake0
    rdrake0 Member Posts: 180
    edited January 2009

    Hi!  I'm 59 years old.  ER/PR+, HER2-, Stage 1, grade 3, Oncotype dx 25.  IDC was only 1.6mm but extensive with at least 3 focal points.  I had a lumpectomy and recision taking out tissue the size of a tennis ball.  Might not have gotten it all yet!  Two different onco docs have said no to chemo.  I was really expecting it.  I'm having a full body scan today (pet) just to check if it is anywhere else in me.  Next week I see the rad doc.What do you guys out there think about the chemo decision? 

    Thanks!

  • Anonymous
    Anonymous Member Posts: 1,376
    edited January 2009

    Chemo, like every other treatment out there has side effects, and it doesn't come with any guarantees.  At some point, the negative effect of those side effects outweighs any benefit that you get from the treatment.  That is why doctors sometimes don't recommend chemo.

    The older you are, the less likely the cancer is to return.  You are also more likely to have other risk factors that make you more susceptible to the serious potential side effects such as cardiac damage.  Oncologists are much quicker to recommend chemo to younger women because they have more years for the cancer to return, and are likely to have more agressive cancers.

    Chemo has been shown to be less effective against slow growing cancers.  You and your oncologist need to take all of those factors into consideration when making decisions for or against adjuvant chemo. 

    What good does it do you to be cancer free, (which you have a really good chance of anyway) if you become significantly incapacitated due to a treatment that you didn't need?

    In reality, for each of us, there are only 2 percentages that matter, 100 or zero.  The cancer either returns, or it doesn't.  We each need to make the treatment choices that we can live peacefully with.

  • Rsszwed
    Rsszwed Member Posts: 1
    edited February 2009

    Hi,  first post also, this is for Nina49.  I am 49 years old and have the identical components as your cancer.  1.5 cm, Estr.+, prog.+, herc.-    My onco score came back yesterday  as a 12.  My oncologist is letting me make the decision.  8% chance of cancer coming back without chemo.  I am looking at all avenues of experience to make my decision.  He did say that with the tamoxifen it would bring the chance down to 5% without chemo.  I forgot to say my nodes are negative and margins were clean.  susan

  • kamico3
    kamico3 Member Posts: 90
    edited February 2009

    nina49-- my understanding was that the percentage for distant recurrence given in the oncotype dx score assumes having taken tamoxifen for 5 years, so I don't think there is an additional drop in percentage for taking hormone therapy, that is included in their calculations. My doctors told me that if I did chemo, in addition to radiation and hormone therapy, it might drop the percentage from 12% to about 10% Can anyone else confirm this my understanding about the oncotype dx score already including the assumption that you have taken the hormone therapy for 5 years?

  • nina49
    nina49 Member Posts: 5
    edited February 2009

    Hi Susan.  This is a tough decision.  My thought today is that if the onco dx score is inconclusive, what would have been the suggested treatment without it?  I know for me it would have been chemo.  I want to talk to my doc tomorrow, because before this test she was going to recommond chemo, and now she cannot definitely tell me I don't need it.  I am still concerned about long term risks and I want her to confirm those for me.  This is by far the toughest decision I have ever had to make.  Thanks for yor input and please let me know what you decide, I will post as well, and good luck with your decision.  We do sound identical in our dx, my margins were clean as well.

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