DCIS & IDC-What Were Your Grades?

Pam,

 I have both the DCIS, Stage IIa, grade 2 and IDC same - also have the rare tubular formation and cribiform -  T 3

I forgot to mention - I am on second round of chemo after left mastectomy - the mastectomy showed another area of DCIS, which was not graded as we already had Dx.  My doc told me they call it a multi-centric cancer, plus two individual cancers - DCIS and IDC ,two tumors to far apart to be considered same - 1.8, 1.3.  I thought IDC stemmed from DCIS - but apparently they consider separate. The Onc combined the sizes of tumors: 3.1 and that is why I am doing chemo - chance of reoccurrance is 25 -30% without chemo.  No nodes, which seems very positive.  Fear of reoccurance or met is weighing on me today.

I don't think my dcis was graded either....at least I can't find anything about it.  But, my IDC was stage 1, grade 3.

hi there...

i had DCIS Grade 1..and i had 2 tiny areas of IDC  1mm and 4mm..both of those were Grade 1.

Hugs...

Kosh

I had a .8 cm IDC tumor, intermediate grade.  My DCIS was more extensive, also intermediate grade.  I also had ADH on the resection,  multiple foci "suggestive of extension of ductal carcinoma in site into lobules".  I haven't figured out what the extension into lobules means.

 Deb

My tumor was 2.1 cm with 20% DCIS.  My DCIS was low grade and my IDLC (both ductal and lobular) was grade 1.  However, I had one positive node, go figure.

My tumor that was about 1 cm with 60% of it being both histologic grade and nuclear grade 1 IDC NOS with tubular features. The other 40% was grade 1 DCIS cribriform type.  ER strongly positive and PR positive. Her-2 negative (1+). Ki-67 5%. No microcalcifications. No necrosis. No venous or lymphatic invasion.  Only one node removed with the SNB and it was negative. The tissue removed in the lumpectomy measured 7.5 cm x 5 cm x 3.0 cm.

My understanding is that DCIS Ductal carcimoma in-situ can develop into IDC invasive ductal carcinoma. so if you have IDC it happened because the DCIS started growing outside the duct. I believe most path reports for IDC will show some DCIS component. Although you can have multiple areas of either DCIS or IDC that aren't related to each other, for example one located at 1 o'clock another at 7 o'clock.

my in-situ carcinoma was grade 2, with invasive DC going to the margins.

When I had the resection there was a focal residual DCIS of 2.5mm of "low nuclear grade, with no invasive DC found. Kind of shocked me that no invasive was found since it went to the margins in the first lumpectomy.

Jaydee, I have read that a wide margin is great. Some doctors think this is the best thing to prevent recurrence (1cm is what they aim for), I had 5mm of clear margins, which is shy of 5mm. But my surgeon was only looking for 2mm, and I have read that he has great success with this margin.

Dejaboo -

Hi.  My DCIS (which was the way more extensive component) was grade 3.  My IDC was grade 2.   By the way, I am also ER+ (though weakly), PR-, and HER2 + (strongly).

Hope that helps !

Jill  

Doesn't the final mast report show the same thing only in more depth Kimbly?

Kimbly? Are you in michigan? SOrry if I've asked that before   Foggy sometimes.  If so, where is St. Johns?

My IDC was 2/3, and my DCIS was HIgh Grade. There's no number. What does all that mean? I'm only interested in the 87% likelyhood of no recurrence with standard chemo and radiation. I'm starting T/H in two weeks. I hope it's less toxic than the A/C.

J'aime, it sounds like you IDC was grade 2 of 3 possible (or mid) and the DCIS was 3 of 3 or high grade.  Hope you have less SE's from the T/H.  Good Luck with that!