Possible to be grade 1 and triple neg?

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Lynette
Lynette Member Posts: 167
edited June 2014 in Triple-Negative Breast Cancer

I haven't had my hormone status results yet but I was wondering whether grade 1 IDC can be triple neg?

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  • tos
    tos Member Posts: 376
    edited August 2008

    Hi Lynette,

    Absoutely a triple negative tumor can be grade 1.  I have been triple negative 2 and a few years later grade 1 and both were IDC.

    If you find that you are triple negative, http://www.tnbcfoundation.org is a great place to go for information and their forum is full of wonderful, smart, supportive people all who are triple negative breast cancer patients, caregivers or survivors.

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  • AnnNYC
    AnnNYC Member Posts: 4,484
    edited August 2008

    Lynette, I had to look for an answer to this.  My initial thought was that this was a very good question, and theoretically it's possible, but perhaps unlikely.


    I found a report of a study of 145 triple-negative breast cancers at NYU Cancer Institute: 11 were Grade 1, 23 were Grade 2, and 111 were Grade 3.

    Here's a link: http://www.sciencedaily.com/releases/2008/04/080411150927.htm

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  • AnnNYC
    AnnNYC Member Posts: 4,484
    edited August 2008

    But Lynette, one thing to remember is that only 15% of breast cancers are triple negative. So, if only 7.5% of triple negative cancers are grade 1 (according to the NYU study), then I think there's probably only about a 1% chance that your grade 1 IDC will come back as triple negative.

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  • Shirlann
    Shirlann Member Posts: 3,302
    edited August 2008

    I was grade one, Triple Negative, but it was stage 4.  (most of the trinegs are stage 4) Tiny cancer, but a triple neg.  I am fine almost 10 years later.  But we will see.

    Gentle hugs, Shirlann 

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  • chumfry
    chumfry Member Posts: 642
    edited August 2008

    Shirlann, you were Stage IV?? Isn't that mets?

    I was under the impression that most triple-negs were Grade 3 because they tend to grow so fast.

    --CindyMN

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  • arby
    arby Member Posts: 126
    edited August 2008

    I was trip-neg and stage 1  supposedly DCIS but they found invasive component the size of a pea when the lumpectomy was done.  I did 35 RAD treatments, that's all.

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  • smithlme
    smithlme Member Posts: 1,322
    edited August 2008

    I was a stage 2 grade 3 triple negative the first time around. Fast growing and aggressive but not a stage 4...

    Linda

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  • Malady
    Malady Member Posts: 32
    edited August 2008

    I was Stage 1, Grade 1 and  triple negative.   I choose not to do chemo even though my Oncologist (who I did not like)  recommended that I have it

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  • bar62
    bar62 Member Posts: 321
    edited August 2008

    I am triple negative grade 3. My Oncologist plugged me into her computer and told me that  my recurrence chances were high>40% without Chemo. She scared me silly so I will have chemo and rad because I had a Lumpectomy.

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  • pinoideae
    pinoideae Member Posts: 1,271
    edited September 2008

    Grade 3 Stage 1, chemo + radiation treatment 7 years ago.  Apparently the majority of these tumors are grade 3.  Research suggests that triple negative breast cancer responds well to chemotherapy, greatly reducing the risk of a recurrence.

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